Sinaflan - instructions for use, dose, side effects, contraindications

Composition:Ingredients per 100 g of ointment: active substance: fluocinolone acetonide - 0.025 g, auxiliary substances: propylene glycol - 4.975 g, petrolatum (vaseline medical) - 80 g, lanolin anhydrous - 5 g, ceresin - 10 g

Description:ointment from light yellow to yellow

Pharmacotherapeutic group:Glucocorticosteroid for topical application

ATX: & nbsp

D.07.A. C.04 Fluocinolone acetonide

Pharmacodynamics:

Glucocorticosteroid (GCS) for external use; inhibits the release of inflammatory mediators. When exposed to the skin, the edge accumulation of neutrophils is prevented, which leads to a decrease in inflammatory exudates and "cytokine production, inhibition of migration of macrophages, a reduction in infiltration and granulation, and has anti-inflammatory and anti-allergic effects.

Pharmacokinetics:

After absorption from the surface of the skin binds to plasma proteins, it is metabolized in the liver with the formation of inactive metabolites. It is excreted mainly by the kidneys.

Indications:

Eczema, atopic dermatitis, simple chronic lichen (limited neurodermatitis), toxicermy, simple allergic dermatitis, seborrheic dermatitis, pruritus, urticaria, pruritus, diaper rash, erythema multiforme exudative, psoriasis (exudative form); red flat lichen, discoid lupus erythematosus, dyshidrosis of brushes, external otitis, burns I st., insect bites.

Contraindications:

Hypersensitivity, cutaneous manifestations of syphilis, skin tuberculosis, diaper rash, rosacea, extensive psoriatic plaques, anogenital itching; skin infections caused by bacteria, viruses, fungi - pyoderma, chickenpox, herpes, actinomycosis, blastomycosis, sporotrichosis, trophic ulcers of the lower leg, associated with varicose veins, erosive and ulcerative lesions of the gastrointestinal tract (GI tract), wounds in the areas of application , skin cancer, nevus, atheroma, melanoma, hemangioma, xanthoma, sarcoma, pregnancy, lactation period, children's age (up to 2 years).

Carefully:

At girls in puberty. 1

Pregnancy and lactation:

The use of Sinaphlana is contraindicated in pregnancy.

A short course of treatment with Sinaflane is possible, provided it is applied to small areas of the skin. It is advisable to suspend breastfeeding while using the drug. .

Dosing and Administration:

Outwardly. On the preliminary wiped with a tampon moistened with antiseptic liquid, the skin is applied a small amount of the drug 2-4 times a day and lightly rubbed. If necessary, you can apply an occlusive bandage, leaving it on the affected surface for up to 3-4 days.It is not allowed to apply under the bandage more than 2 g / day.

Ointment is preferable to use in dry forms of dermatoses.

Side effects:

Side effect

Burning, itching, steroid acne, striae, dry skin, folliculitis. With prolonged use - skin atrophy, local hirsutism, hypertrichosis, telangiectasia, purpura, skin pigmentation disorders, alopecia, especially in women, secondary immunodeficiency (exacerbation of chronic infectious diseases, generalization of the infection process, development of opportunistic infections); when applied to large surfaces, systemic manifestations are possible (gastritis, steroid stomach ulcer, adrenal insufficiency, Itenko-Cushing syndrome, steroid diabetes mellitus, slowing of reparative processes).

Overdose:

Symptoms: itching and burning of the skin at the site of application, hyperglycemia, glucosuria, Itenko-Cushing syndrome.

Treatment: symptomatic on the background of a gradual withdrawal of the drug ..

Interaction:

Compatible with antimicrobial drugs (LS). Reduces the activity of antihypertensive, diuretic, antiarrhythmic drugs, potassium preparations (K +).

Diuretics (except potassium-sparing) increase the risk of hypokalemia.

Special instructions:

The drug is not intended for use in ophthalmology.

Apply only short courses on small areas of the skin. It is recommended to wear loose clothes during treatment.

Effect on the ability to drive transp. cf. and fur:

There is no evidence of the influence of Sinaflane on the ability to drive and

work with technology.

Form release / dosage:

Ointment for external use 0,025%.

Packaging:

For 15 g in tubes are aluminum. Each tube together with the instruction for use is placed in a pack of cardboard.

Storage conditions:

In a dry place at a temperature of 12 ° C to 15 ° C. Keep out of the reach of children.

Shelf life:

5 years. Do not use after the expiry date shown on the package.

Terms of leave from pharmacies:On prescription

Registration number:LS-001519

Date of registration:19.09.2011

The owner of the registration certificate:Promomed Rus, Open CompanyPromomed Rus, Open Company Russia

Manufacturer: & nbsp

BIOCHEMIST, OJSC Russia

Information update date: & nbsp20.10.2015

Illustrated instructions

Instructions

Sinaflan (Sinaflan )