Sinaflan - instructions for use, dose, side effects, contraindications

Has anti-inflammatory, anti-allergic, antiexudative and antipruritic effect. When exposed to the skin, the edge accumulation of neutrophils is prevented, which leads to a decrease in inflammatory exudate and production of cytokines; inhibition of migration of macrophages, reduction of infiltration and granulation.

Pharmacokinetics:

After absorption from the surface of the skin it binds to plasma proteins, undergoes a metabolism that occurs mainly in the liver. It is excreted by the kidneys.

Indications:

Acute and chronic inflammatory and allergic skin diseases nemikrobnoy etiology accompanied by dryness of the skin (seborrheic dermatitis, eczema various genesis and localization, neurodermatitis, pruritus, psoriasis, sunburn, insect bites).

Contraindications:

Hypersensitivity, cutaneous manifestations of syphilis, skin tuberculosis, diaper rash, rosacea, extensive psoriatic plaques, anogenital itching; Skin infections caused by bacteria, viruses, fungi - pyoderma, chicken pox, herpes, actinomycosis,blastomycosis, sporotrichosis, leg sores associated with varicose veins, erozivnoyazvennye lesions of the gastrointestinal tract, wounds in the areas of applications, skin cancer, mole, atheroma, melanoma, hemangioma, xanthoma, sarcoma, pregnancy, lactation, children's age (up to 2 years).

Carefully:

Applied in girls during puberty.

Dosing and Administration:

Adults and children older than 2 years externally.

On the previously wiped with a tampon moistened with antiseptic liquid, the skin is applied a small amount of the drug 2-4 times a day and lightly rubbed. The duration of treatment depends on the nature of the disease and is usually 5-10 days, with a long course of the disease to 25 days.

With limited lesions to enhance the effect of ointment can be used for occlusive dressing. It is not allowed to apply more than 2 g of ointment per day to the bandage. Ointment is preferable to use in dry forms of dermatoses.

Side effects:

Burning, itchy skin, dry skin, "steroid" acne, folliculitis. It is possible to develop secondary infectious lesions of the skin and atrophic changes in it.With long-term use - secondary immunodeficiency, hypertrichosis, alopecia, especially in women, skin atrophy, hirsutism, at the site of the drug, telangiectasia, purpura, pigmentation disorder. When applied to extensive surfaces, systemic manifestations are possible (gastritis, steroid ulcer of the stomach, adrenal insufficiency, Itenko-Cushing syndrome,

"steroid" diabetes mellitus, striae, slowing of reparative processes).

Overdose:

Itching, burning of the skin on the site of ointment application, hyperglycemia, glucosuria, Itenko-Cushing syndrome. Treatment: symptomatic on the background of a gradual withdrawal of the drug.

Interaction:

Compatible with antimicrobial drugs.

Reduces the activity of antihypertensive, diuretic, antiarrhythmic drugs, potassium preparations.

Diuretics (except potassium-sparing) increase the risk of hypokalemia.

During treatment with glucocorticosteroids, vaccination and immunization should not be carried out, due to the immunosuppressive effect of the drug.

Special instructions:

Apply only short courses on small areas of the skin. The drug should not be applied to the face. Avoid contact with eyes.Duration of use in children should not exceed 5 days. It is recommended to wear loose clothes during treatment.

In patients with ordinary or rosacea, treatment may aggravate the disease. To prevent local infectious complications, it is recommended to appoint in combination with antimicrobial agents.

Use with caution in individuals with existing atrophic skin changes, especially in the elderly.

Form release / dosage:

Ointment for external use 0,025%.

Packaging:

For 10 g or 15 g in aluminum tubes with bushonami. Each tube together with the instruction for use is placed in a pack of cardboard.

Storage conditions:

In a dry place at a temperature of 12 to 15 ° C. Keep out of the reach of children.

Shelf life:

Shelf life: 5 years.

Do not use the product after the expiry date printed on the package.

Terms of leave from pharmacies:Without recipe

Registration number:PL-000359

Date of registration:22.02.2011

The owner of the registration certificate:ALTAYVITAMINS, CJSC ALTAYVITAMINS, CJSC Russia

Manufacturer: & nbsp

ALTAYVITAMINS, CJSC Russia

Representation: & nbspALTAYVITAMINS, CJSCALTAYVITAMINS, CJSC

Information update date: & nbsp20.10.2015

Illustrated instructions

Instructions

Sinaflan (Sinaflan )