Local reactions: burning, skin itching, acne, post-steroid vascular purpura, suppression of epidermal growth, skin atrophy and telangiectasia, dry skin, perioral dermatitis, striae, folliculitis, increased hair loss or alopecia, melanoderma or discoloration of the skin, secondary infected skin lesionspropensity to develop pyoderma and candidiasis, ecchymosis).
From the side gastrointestinal tract: vomiting, pancreatitis, bleeding and perforation of the gastrointestinal tract, flatulence, hiccough, nausea, steroid ulcer of the stomach and duodenum, esophagitis, increased or decreased appetite, increased activity of hepatic enzymes.
From the side endocrine system: suppression of adrenal function, suppression of the function of the pituitary-adrenal system,steroid diabetes or the manifestation of latent diabetes mellitus, delayed sexual development in children, menstrual irregularities, Itenko-Cushing's syndrome, reduced tolerance to carbohydrates, and slowed growth in children.
From the side metabolism: negative nitrogen balance due to protein catabolism, hypocalcemia, weight gain, sweating.
From the side musculoskeletal system: growth retardation and ossification processes in children (premature closure of epiphyseal growth zones), muscle tendon rupture, muscle weakness, steroid myopathy, osteoporosis (very rarely pathological fractures, aseptic necrosis of the head of the humerus and femur), muscle mass reduction (atrophy).
From the side of cardio-vascular system: loss of potassium, arrhythmia, arterial hypertension, steroid myopathy, heart failure (development or enhancement of symptoms), characteristic of hypokalemia, hypercoagulation, hypokalemic alkalosis, bradycardia (up to cardiac arrest), ECG changes, increased blood pressure, thrombosis. In patients with acute myocardial infarction - slowing the formation of scar tissue, the spread of the foci of necrosis, rupture of the heart muscle.
From the side nervous system: headache, delirium, disorientation, hallucinations, depression, insomnia, vertigo, convulsive seizures, increased intracranial pressure, euphoria, manic-depressive psychosis, nervousness or anxiety, dizziness, pseudotumor of the cerebellum.
From the side view: posterior subcapsular cataract, trophic corneal changes, exophthalmos, increased intraocular pressure (with possible damage to the optic nerve), propensity to develop secondary infection (bacterial, fungal, viral).
Other: with prolonged use and / or application to large body surfaces: peripheral edema, slowing down the processes of regeneration, secondary immunodeficiency (exacerbation of chronic infectious diseases, reduced resistance to infections - generalization of the infectious process, the development of opportunistic infections), allergic reactions (urticaria, maculopapular rash).