Hydrocortisone - instructions for use, dose, side effects, contraindications

Excipients: petrolatum medical - 45.0 g, lanolin anhydrous - 10.0 g, pentol 5.0 g, stearic acid - 3.0 g, nipagine - 0.08 g, nipose - 0.02 g, purified water - 35.9 g.

Description:

Ointment is white with a yellowish tint or light yellow color.

Pharmacotherapeutic group:Glucocorticosteroid for topical application

ATX: & nbsp

S.01.B.A.02 Hydrocortisone

H.02.A.B.09 Hydrocortisone

D.07.A.A.02 Hydrocortisone

Pharmacodynamics:

Hydrocortisone is a synthetic glucocorticosteroid drug for topical application.

Has anti-inflammatory, anti-edematous, antipruritic effect.

Pharmacokinetics:

After application, it accumulates in the epidermis (mainly in the granular layer). Metabolized directly in the epidermis, and later in the liver. It is excreted by the kidneys and with bile.

Indications:

Hydrocortisone ointment 1% is used for inflammatory and allergic skin diseases of non-microbial etiology: eczema, allergic and contact dermatitis,neurodermatitis, psoriasis.

Contraindications:

The use of the drug is contraindicated with hypersensitivity to hydrocortisone or other components of the drug, with wound, ulcerative lesions, bacterial, viral and fungal skin diseases, with skin tuberculosis and syphilitic skin lesions.

Rosacea, vulgar acne, perioral dermatitis, skin tumors, children under 2 years.

The drug is not prescribed for pregnant women.

Carefully:With diabetes.

Pregnancy and lactation:

Glucocorticosteroids penetrate the placenta. The effect on the fetus can be particularly pronounced when the drug is applied to large surfaces. It is recommended that special care be taken when using the drug during pregnancy and lactation.

Dosing and Administration:

Locally. Ointment is applied a thin layer on the affected skin 2-3 times a day. The duration of the course of treatment depends on the nature of the disease and the effectiveness of the therapy, amounting, as a rule. 6-14 days, with persistent disease, it can be prolonged up to 20 days. On limited foci, occlusal dressings can be used to enhance the effect.When ointment is used in children from 2 years and older, the total duration of treatment should be limited and the measures leading to increased resorption of steroid absorption (warming, fixative and occlusive dressings) should be excluded.

Side effects:

There may be phenomena of individual intolerance in the form of hyperemia, swelling and itching in the places of ointment application. With prolonged use, it is also possible to develop secondary infectious skin lesions, atrophic changes in it. hypertrichosis. To prevent infectious skin lesions, the drug is recommended to be administered in combination with antibacterial and antifungal agents.

With prolonged use of the ointment or the use of an occlusive dressing, especially on large lesions, it is possible to develop hypercortinism, as a manifestation of resorptive action, hydrocortisone acetate.

Overdose:

With prolonged use of the drug in large doses, symptoms of hypercorticism may appear.

Interaction:Not described.

Special instructions:

Children

In cases of use of the drug in children, on the face area or under occlusive dressings, the duration of the course of treatment should be reduced.

In childhood, suppression of the function of the adrenal cortex can develop faster. In addition, there may be a decrease in the excretion of growth hormone. When using the drug for a long time, it is necessary to observe the body weight, growth, plasma cortisol level. Avoid contact with ointment in the eyes. Children under 12 years of age, the drug is prescribed only under strict medical supervision. If after 7 days of application there is no improvement or a worsening of the condition occurs, as well as if the symptoms resume after a few days after the drug has been discontinued, the drug should be discontinued and consulted with the doctor. For long-term treatment and / or application to large surfaces, it is recommended to prescribe a diet with sodium restriction and an elevated K + content; to introduce into the body a sufficient amount of protein. It is necessary to monitor blood pressure. blood glucose, blood coagulability, diuresis, body weight of the patient, plasma cortisol level.

Effect on the ability to drive transp. cf. and fur:Not described.

Form release / dosage:

Ointment for external use.

Packaging:

Ointment in tubes of aluminum for 10 g.Each tube together with the instruction for use is placed in a pack of cardboard.

Storage conditions:

At a temperature not higher than 25 ° C, out of the reach of children.

Shelf life:

3 years. Do not use after expiry date.

Terms of leave from pharmacies:Without recipe

Registration number:P N002434 / 01-2003

Date of registration:19.05.2008 / 29.10.2012

Expiration Date:Unlimited

The owner of the registration certificate:MUROMSKY INSTRUMENT-MAKING PLANT, OJSC MUROMSKY INSTRUMENT-MAKING PLANT, OJSC Russia

Manufacturer: & nbsp

MUROMSKY INSTRUMENT-MAKING PLANT, OJSC Russia

Information update date: & nbsp05.04.2017

Illustrated instructions

Instructions

Hydrocortisone (Hydrocortisone)