Laticort - instructions for use, dose, side effects, contraindications

Laticort® is an active, synthetic, non-halogenated glucocorticosteroid drug for topical use. It has a quick anti-inflammatory, anti-edematous, antipruritic and anti-allergic action. Due to local vasoconstrictive action reduces exudative reactions.

The use of the cream in recommended doses does not cause suppression of the hypothalamic-pituitary-adrenal system.

Pharmacokinetics:

Suction

After application, the active substance accumulates in the epidermis, mainly in the granular layer.

Metabolism

Hydrocortisone butyrate, absorbed through the skin, is metabolized to hydrocortisone and other metabolites directly in the epidermis and subsequently, in the liver.

Excretion

Metabolites and a small part of unchanged hydrocortisone butyrate is excreted by the kidneys and with bile.

Indications:

Uninfected dermatoses sensitive to local glucocorticosteroids, including:

- seborrheic dermatitis;

- atopic dermatitis;

- erythroderma;

- contact eczema;

- psoriasis;

- red flat lichen;

Insect bites.

Contraindications:

- Hypersensitivity to the components of the drug;

- bacterial, viral and fungal skin infections;

- acne vulgaris, rosacea;

- perioral dermatitis;

- post-vaccination period;

- violation of the integrity of the skin (wounds, ulcers);

- skin tumors;

- tuberculosis or syphilitic skin lesions;

- children age up to 6 months, with itching in the anus - up to 12 years.

Carefully:

Diabetes mellitus, tuberculosis (systemic damage).

Pregnancy and lactation:

The use of Laticort® in pregnant women is allowed in cases when, according to the attending physician, the potential benefit for a pregnant woman prevails over the possible risk to the fetus. In these cases, the application should be short and limited to small areas of the skin. It is not recommended to use in the first trimester of pregnancy.

During breastfeeding, use for a short time on a small surface of the skin and not apply to the skin of the breast.

Dosing and Administration:

Outwardly.

Have of adults: a small amount of the drug is applied to the affected skin 1-3 times a day. The course of treatment is 1-3 weeks. The dose of the drug used during the week should not exceed 30-60 g. To improve the penetration the drug is applied by massaging movements. In cases of refractory disease, for example, in the localization of dense psoriatic plaques on the elbows, knees, the drug should be used under occlusive dressings.

Children: the drug is used from 6 months of age.

In childhood, suppression of the function of the adrenal cortex can develop more quickly. In addition, there may be a decrease in the excretion of growth hormone.When using the drug for a long time, it is necessary to observe the body weight, growth, plasma cortisol level. In control studies in children who received 30-60 grams of Laticort® cream weekly, there were no abnormalities in the adrenal cortex.

When using the drug on the face or under occlusive dressings (diapers, diapers), a greater degree of absorption is possible, so it is recommended to apply a minimal dose of the drug. Treatment should be short-term and under the supervision of a doctor.

Side effects:

Side effects are rare and are reversible.

Local Reactions: rarely - skin irritation.

With long-term use and / or application to large surfaces, with the use of occlusive dressings, acne-like changes, hypopigmentation, sweating, folliculitis, striae, skin atrophy, hypertrichosis, secondary skin infections are possible in rare cases.

In rare cases, the development of allergic contact dermatitis.

Overdose:

Data on the overdose of Laticort® cream is not available. With prolonged use of the drug in large doses, symptoms of hypercorticism may appear.

Treatment: symptomatic on the background of a gradual withdrawal of the drug.

Interaction:

Data on the drug interaction of Laticort® cream with other agents are not available.

Special instructions:

Avoid using Latticort® cream in the eyes. If a secondary bacterial or fungal infection develops, an external antibacterial or antifungal agent should be prescribed. With extreme caution, the drug should be applied to the skin of the face due to the possibility of side effects (telangiectasia, atrophy, perioral dermatitis).

If after 7 days of application there is no improvement or if there is a worsening of the condition, and also if the symptoms recur after a few days after cancellation, the drug should be discontinued and consulted by a doctor. Although the use of large doses of the drug for a long time, especially with the use of occlusive dressings, can lead to an increase in the content of cortisol in the blood plasma, this is never accompanied by a decrease in the reactivity of the pituitary-adrenal system, and the abolition of the drug leads to a rapid normalization of cortisol production.

With caution use the drug in cases of already existing atrophic skin conditions, especially in the elderly.

The risk of side effects is lower than when using halogenated steroids.

Laticort® cream is recommended for acute inflammatory conditions with wetness.

Effect on the ability to drive transp. cf. and fur:The drug does not limit the psychophysical ability, the ability to drive vehicles and maintain machinery in motion.

Form release / dosage:

Cream for external use 0,1%.

Packaging:

For 15 grams in aluminum, inside lacquered, lithographed tubes.

1 The tube with instructions for use is placed in a cardboard box.

Storage conditions:

Store at a temperature of 5 to 15 ° C.

Keep out of the reach of children.

Shelf life:

2 of the year. Do not use after expiry date.

Terms of leave from pharmacies:Without recipe

Registration number:П N012869 / 02

Date of registration:02.10.2009 / 18.02.2015

Expiration Date:Unlimited

Date of cancellation:2017-11-28

The owner of the registration certificate:VALEANT, LLC VALEANT, LLC Russia

Manufacturer: & nbsp

Elfa Pharmaceutical Factory Poland

Representation: & nbspVALEANT LLC VALEANT LLC Russia

Information update date: & nbsp12.03.2018

Illustrated instructions

Instructions

Laticort® (Laticort®)