Laticort - instructions for use, dose, side effects, contraindications

Laticort® is an active, synthetic, non-halogenated glucocorticosteroid drug for topical use. It has a quick anti-inflammatory, anti-edematous, antipruritic and anti-allergic action. Due to local vasoconstrictive action reduces exudative reactions.

The use of the solution at recommended doses does not cause suppression of the hypothalamic-pituitary-adrenal system.

Pharmacokinetics:

Suction

After application, the active substance accumulates in the epidermis, mainly in the granular layer.

Metabolism

Hydrocortisone butyrate, absorbed through the skin, is metabolized to hydrocortisone and other metabolites directly in the epidermis and subsequently - in the liver.

Excretion

Metabolites and a small part of unchanged hydrocortisone 17-butyrate is excreted by the kidneys and bile.

Indications:

Superficial, uninfected, sensitive to local glucocorticosteroids skin diseases that occur with excessive keratinization:

- seborrheic dermatitis;

- atopic dermatitis;

- erythroderma;

- contact eczema;

- psoriasis of the scalp and skin;

- red flat lichen;

- insect bites.

Contraindications:

- Hypersensitivity to the components of the drug;

- bacterial, viral and fungal skin infections;

- acne vulgaris, rosacea;

- perioral dermatitis;

- violation of the integrity of the skin (wounds, ulcers), skin tumors;

- tuberculosis or syphilitic skin lesions;

- post-vaccination period;

- viral skin diseases;

- children age up to 6 months, with itching in the anus - up to 12 years.

Carefully:

Diabetes mellitus, tuberculosis, pregnancy (I trimester), lactation.

Pregnancy and lactation:

The use of Laticort® solution in pregnant women is allowed in cases when, according to the attending physician, the potential benefit for the pregnant woman prevails over the possible risk to the fetus. In these cases, the application should be short and limited to small areas of the skin. It is not recommended to use in the first trimester of pregnancy.

During breastfeeding, use for a short time on a small surface of the skin and not apply to the skin of the breast.

Dosing and Administration:

Outwardly.

A small amount of the drug is applied to the affected skin 1-3 times a day. The course of treatment is 1-3 weeks. To improve penetration, the drug is applied by massaging movements. In cases of refractory disease, for example, in the localization of dense psoriatic plaques on the elbows, knees, the drug should be used under occlusive dressings. The dose of the drug used during the week should not exceed 30-60 g.

Application in childhood

In childhood, suppression of the function of the adrenal cortex can develop more quickly.In addition, there may be a decrease in the excretion of growth hormone. When using the drug for a long time, it is necessary to observe the body weight, growth, plasma cortisol level.

When using the drug on the face or under occlusive dressings (diapers, diapers), a greater degree of absorption is possible, so it is recommended to apply a minimal dose of the drug. Treatment should be short-term and under the supervision of a doctor.

Side effects:

Side effects are rare and are reversible.

Local reactions: rarely - skin irritation.

With long-term use and / or application to large surfaces, with occlusive dressings, acne-like changes, hypopigmentation, sweating, folliculitis, striae, skin atrophy, hypertrichosis and secondary skin infections are rare in rare cases.

In rare cases, the development of allergic contact dermatitis.

Overdose:

There is no evidence of an overdose of Latticort®. With prolonged use of the drug in large doses, symptoms of hypercorticism may appear.

Treatment: symptomatic on the background of a gradual withdrawal of the drug.

Interaction:

Data on the drug interaction of the Latticort® solution with other agents are not available.

Special instructions:

Do not use Latticort® solution in the eyes.

If a secondary bacterial or fungal infection develops, an external antibacterial or antifungal agent should be prescribed.

With extreme caution, the drug should be applied to the skin of the face due to the possibility of side effects (telangiectasia, atrophy, perioral dermatitis).

If after 7 days of application there is no improvement or if there is a worsening of the condition, and also if the symptoms recur after a few days after cancellation, the drug should be discontinued and consulted by a doctor.

With caution use the drug in cases of already existing atrophic skin conditions, especially in the elderly.

The risk of side effects when using the Latticort® solution is lower than when using halogenated steroids.

Laticort® solution is recommended for acute inflammatory conditions with wetness.

It is indicated for the treatment of diseases of the scalp.

Effect on the ability to drive transp. cf. and fur:

The drug does not limit the psychophysical ability, the ability to drive vehicles and maintain machinery in motion.

Form release / dosage:

Solution for external use, 0.1%.

Packaging:

To 20 ml in polyethylene bottles.

Each bottle has a label.

1 bottle together with the instruction for use is placed in a cardboard box.

Storage conditions:

Store at a temperature of 5 to 15 ° C.

Keep out of the reach of children.

Shelf life:

2 of the year.

Do not use after expiry date.

Terms of leave from pharmacies:Without recipe

Registration number:П N012869 / 01

Date of registration:16.09.2009 / 04.10.2013

Expiration Date:Unlimited

Date of cancellation:2017-11-14

The owner of the registration certificate:VALEANT, LLC VALEANT, LLC Russia

Manufacturer: & nbsp

PHARMACEUTICAL WORKS JELFA, S.A. Poland

Representation: & nbspVALEANT LLC VALEANT LLC Russia

Information update date: & nbsp11.03.2018

Illustrated instructions

Instructions

Laticort® (Laticort®)