Potassium permanganate - instructions for use, dose, side effects, contraindications

Antiseptic. When in contact with organic matter, it releases an atomic oxygen. The oxide formed in the reduction of potassium permanganate potassium oxide forms complex compounds with proteins, albumins (at the expense of this potassium permanganate in small concentrations has astringent, and in concentrated solutions - irritating, cauterizing and tanning action). It also has a deodorizing effect.Effective in the treatment of burns and ulcers.

Potassium permanganate ability to neutralize some poisons underlies the use of its solutions for gastric lavage for poisoning and foodborne infections. If ingested, absorbed, having a hematotoxic effect (leads to the development of methemoglobinemia).

The drug belongs to list No. 4 of the list of narcotic drugs, psychotropic substances and their precursors subject to control in the Russian Federation.

Indications:

Lubrication of ulcerous and burn surfaces - infected wounds, ulcers and skin burns.

Rinsing of the mouth and oropharynx - with infectious and inflammatory diseases of the mucous membrane of the oral cavity and the oropharynx (including angina).

For rinsing and syringing with gynecological and urological diseases - colpitis and urethritis.

For lavage - the stomach with poisoning caused by the ingestion of alkaloids (morphine, aconitine, nicotine), hydrocyanic acid, phosphorus, quinine; skin - if you hit it with aniline; eye - when affected by poisonous insects.

Contraindications:

Hypersensitivity.

Pregnancy and lactation:

After consulting a doctor, the drug may be administered according to the instructions if the expected benefit to the mother exceeds the potential risk to the fetus and the baby.

Dosing and Administration:

Outer, local. In the form of aqueous solutions for washing the wounds (0.1-0.5%), for rinsing the mouth and throat (0.01-0.1%), for lubricating ulcer and burn surfaces (2 - 5%), for douching ( 0,02 - 0,1%), in gynecological and urological practice, as well as gastric lavage during poisoning.

To dissolve - several crystals are placed in a glass with warm water and mixed, the solution is used only freshly prepared.

Side effects:

Allergic reactions are possible, when using concentrated solutions - burns and irritation.

Overdose:

Symptoms: severe pain in the oral cavity, along the esophagus, in the abdomen, vomiting, diarrhea; the oral and pharyngeal mucosa is edematic, dark brown, purple, laryngeal edema, mechanical asphyxia, burn shock, motor excitement, seizures, parkinsonism, hemorrhagic colitis, nephropathy, hepatopathy. With reduced acidity of gastric juice, it is possible to developMethemoglobinemia with pronounced cyanosis and dyspnea. The lethal dose for children is about 3 g, for adults - 0.3 - 0.5 g / kg.

Treatment: methylene blue (50 ml 1 % solution), ascorbic acid (in / in - 30 ml of a 5% solution), cyanocobalamin - up to 1 mg, pyridoxine (in / m - 3 ml of 5% solution).

Interaction:

Chemically incompatible with certain organic substances (coal, sugar, tannin) and easily oxidizing substances - an explosion may occur.

Effect on the ability to drive transp. cf. and fur:

The use of the drug in accordance with the instructions does not affect the management of vehicles and occupations of potentially hazardous activities requiring increased concentration and speed of psychomotor reactions.

Form release / dosage:Powder for solution for local and external use.

Packaging:

For 3 g in bottles of orange glass with a screw neck type PV or in bottles from drota for medicines; or in cans of orange glass with a triangular aureole. Vials / cans with an equal number of instructions for medical use are placed in a group package.

Storage conditions:

List of IV BCPC precursors.In a dry place at a temperature of no higher than 25 ° C.

Keep out of the reach of children.

Shelf life:

5 years.

Do not use after the expiration date.

Terms of leave from pharmacies:Without recipe

Registration number:P N003587 / 01

Date of registration:05.10.2009 / 29.12.2011

Expiration Date:Unlimited

The owner of the registration certificate:YAROSLAVSK PHARMACEUTICAL FACTORY, CJSC YAROSLAVSK PHARMACEUTICAL FACTORY, CJSC Russia

Manufacturer: & nbsp

YAROSLAVSK PHARMACEUTICAL FACTORY, CJSC Russia

Information update date: & nbsp26.11.2017

Illustrated instructions

Instructions

Potassium permanganate (Potassium permanganate)