Potassium permanganate (Potassium permanganate)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
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Active substancePotassium permanganatePotassium permanganate
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  • Potassium permanganate
    powder locally externally 
    TULA PHARMACEUTICAL FACTORY, LTD.     Russia
  • Potassium permanganate
    powder locally externally 
    TATHIMFARMPREPARATY, JSC     Russia
  • Potassium permanganate
    powder locally externally 
    YAROSLAVSK PHARMACEUTICAL FACTORY, CJSC     Russia
  • Potassium permanganate
    powder locally externally 
    UPDATE OF PFC, CJSC     Russia
  • Potassium permanganate
    powder locally externally 
    LEKAR, LLC     Russia
    • Dosage form: & nbspPowder for solution for local and external use
    Composition:Potassium permanganate - 3 g, 5 g, 15 g.
    Description:Dark or red-violet crystals or a fine crystalline powder with metallic luster. When the drug interacts with some organic or easily oxidizable substances, an explosion may occur.
    Pharmacotherapeutic group:Antiseptic
    ATX: & nbsp

    D.08.A.X   Other antiseptics and disinfectants

    D.08.A.X.06   Potassium permanganate

    Pharmacodynamics:

    Antiseptic. When in contact with organic matter, it releases an atomic oxygen. The oxide formed during the restoration of potassium permanganate potassium oxide forms complex compounds with proteins - albumins (due to this potassium permanganate in small concentrations has astringent, and in concentrated solutions - irritating, cauterizing and tanning action). It also has a deodorizing effect. Effective in the treatment of burns and ulcers.

    Potassium permanganate ability to neutralize some poisons underlies the use of its solutions for washing the stomach with poisoning.

    If ingested, absorbed, having a hematotoxic effect (leads to the development of methemoglobinemia).

    The drug belongs to list No. 4 of the list of narcotic drugs, psychotropic substances and their precursors subject to control in the Russian Federation.

    Indications:

    Lubrication of ulcerous and burn surfaces - infected wounds, ulcers and skin burns.

    Rinsing of the mouth and oropharynx - for infectious and inflammatory diseases of the mucous membrane of the oral cavity and oropharynx (including with angina).

    For washing and syringing with gynecological and urological diseases - colpitis, urethritis.

    For lavage - the stomach with poisoning caused by intake of alkaloids (morphine, aconitine, nicotine), prussic acid, phosphorus, quinine; skin - if you hit it with aniline; eye - when affected by poisonous insects.
    Contraindications:Hypersensitivity to the drug.
    Pregnancy and lactation:

    During pregnancy and during breastfeeding, the prescription of the drug is possible if the potential benefit to the mother exceeds the possible risk to the fetus or the baby.

    Dosing and Administration:

    Outer, local. In the form of aqueous solutions for washing the wounds (0.1-0.5%), for rinsing the mouth and throat (0.01-0.1%), for lubricating ulcer and burn surfaces (2 - 5%), for douching ( 0,02 - 0,1%) in gynecological and urological practice, as well as gastric lavage during poisoning.

    To dissolve - several crystals are placed in a glass with warm water and mixed, the solution is used only freshly prepared.

    Side effects:

    Allergic reactions, when using concentrated solutions - burns and irritation.

    Overdose:

    Symptoms: sharp pain in the oral cavity, along the esophagus, in the abdomen, vomiting, diarrhea; mucous membrane of the oral cavity and pharyngeal edema, dark brown, violet, laryngeal edema possible, development of mechanical asphyxia, burn shock, motor excitement, seizures, parkinsonism, hemorrhagic colitis, nephropathy, hepatopathy.With reduced acidity of gastric juice, the development of methemoglobinemia with pronounced cyanosis and dyspnea is possible. The lethal dose for children is about 3 g, for adults - 0.3 - 0.5 g / kg.

    Treatment: methylthioninium chloride (50 ml of a 1% solution); ascorbic acid (in / in - 30 ml of a 5% solution); cyanocobalamin - up to 1 mg; pyridoxine (in / m - 3 ml of 5% solution).
    Interaction:

    It is chemically incompatible with certain organic substances (coal, sugar, tannin) and easily oxidizing substances.

    Effect on the ability to drive transp. cf. and fur:There is no information.
    Form release / dosage:Powder for solution for local and external use.
    Packaging:

    By 3, 5 or 15 g of the drug in bottles of glass with a screw mouth, sealed with plastic caps and caps screwed.

    By 3, 5 or 15 g of the drug in polyethylene bags, or in packages, heat-sealing from a colorless thermoformable film.

    Vials, packages are placed together with an equal number of instructions for use in group packaging.

    Storage conditions:

    In a dry place.

    List No. 4 of the list of narcotic drugs, psychotropic substances and their precursors.

    Keep out of the reach of children.

    Shelf life:

    5 years. Do not use after the expiration date.

    Terms of leave from pharmacies:Without recipe
    Registration number:LP-001123
    Date of registration:03.11.2011 / 11.09.2012
    Expiration Date:Unlimited
    The owner of the registration certificate:TULA PHARMACEUTICAL FACTORY, LTD. TULA PHARMACEUTICAL FACTORY, LTD. Russia
    Manufacturer: & nbsp
    Information update date: & nbsp26.11.2017
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