Potassium permanganate - instructions for use, dose, side effects, contraindications

Antiseptic. When in contact with organic matter, it releases an atomic oxygen. The oxide formed in the reduction of potassium permanganate potassium oxide forms complex compounds with proteins - albumins (due to this potassium permanganate in small concentrations has astringent, and in concentrated solutions - irritating, cauterizing and tanning action). It also has a deodorizing effect.Effective in the treatment of burns and ulcers. Potassium permanganate ability to neutralize some poisons underlies the use of its solutions for washing the stomach with poisoning.

When ingested, absorbed, providing hematotoxic effect (leads to the development of methemoglobinemia).

The drug belongs to the list number 4 of the list of narcotic drugs, psychotropic substances and their precursors, subject to control in the Russian Federation.

Indications:

Lubrication of ulcerous and burn surfaces - infected wounds, ulcers and skin burns.

Rinsing of the mouth and oropharynx - for infectious and inflammatory diseases of the mucous membrane of the mouth and oropharynx (including angina).

For rinsing and syringing with gynecological and urological diseases - colpitis and urethritis.

For lavage - the stomach with poisoning caused by intake of alkaloids (morphine, aconitine, nicotine), prussic acid, phosphorus, quinine.

Contraindications:

Hypersensitivity.

Dosing and Administration:

Outer, local. In the form of aqueous solutions for washing the wounds (0.1-0.5%), for rinsing the mouth and throat (0.01-0.1%), for lubricating ulcer and burn surfaces (2-5%), for syringing (0.02 - 0.1%) in gynecological and urological practice, as well as gastric lavage for poisoning.

To dissolve - several crystals are placed in a glass with warm water and mixed, the solution is used only freshly prepared.

Side effects:

Allergic reactions, when using concentrated solutions - burns and irritations.

Overdose:

Symptoms: severe pain in the oral cavity, along the esophagus, in the abdomen, vomiting, diarrhea; mucous membrane of the oral cavity and pharynx - edematic, dark brown, violet, laryngeal edema possible, development of mechanical asphyxia, burn shock, motor excitement, seizures, parkinsonism, hemorrhagic colitis, nephropathy, hepatopathy. With reduced acidity of gastric juice, the development of methemoglobinemia with pronounced cyanosis and respiratory distress is possible. The lethal dose for children is about 3 g, for adults 0.3-0.5 g / kg.

Treatment: methylene blue (50 ml of 1% solution), ascorbic acid (in / in - 30 ml of a 5% solution), cyanocobalamin - up to 1 mg, pyridoxine (in / m - 3 ml of 5% solution).

Interaction:

Chemically incompatible with certain organic substances (coal, sugar, tannin) and easily oxidizable substances - an explosion may occur.

Form release / dosage:Powder for solution preparation for external and local use.

Packaging:

3 grams, 5 grams, 15 grams in glass bottles with a screw neck, sealed with plastic lids with blades or without blades.

3 grams, 5 grams per pack of polyethylene film.

On labels, packages stick labels self-adhesive.

Each vial, a package with instructions for use is placed in a pack of cardboard.

Storage conditions:

List of IV precursors. In a dry place at a temperature of 15 to 25 ° C.

Keep out of the reach of children.

Shelf life:

5 years.

Do not use after the date shown on the package.

Terms of leave from pharmacies:Without recipe

Registration number:P N003203 / 01

Date of registration:05.02.2009 / 14.05.2015

Expiration Date:Unlimited

The owner of the registration certificate:UPDATE OF PFC, CJSC UPDATE OF PFC, CJSC Russia

Manufacturer: & nbsp

UPDATE, PFC CJSC Russia

Information update date: & nbsp26.11.2017

Illustrated instructions

Instructions

Potassium permanganate (Potassium permanganate)