Potassium permanganate (Potassium permanganate)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
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Active substancePotassium permanganatePotassium permanganate
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  • Potassium permanganate
    powder locally externally 
    TULA PHARMACEUTICAL FACTORY, LTD.     Russia
  • Potassium permanganate
    powder locally externally 
    TATHIMFARMPREPARATY, JSC     Russia
  • Potassium permanganate
    powder locally externally 
    YAROSLAVSK PHARMACEUTICAL FACTORY, CJSC     Russia
  • Potassium permanganate
    powder locally externally 
    UPDATE OF PFC, CJSC     Russia
  • Potassium permanganate
    powder locally externally 
    LEKAR, LLC     Russia
    • Dosage form: & nbspPowder for solution for local and external use
    Composition:

    Dosage 3 g

    Active substance: Potassium permanganate 3.0 g.

    Dosage 5 g

    Active substance: Potassium permanganate 5.0 g.

    Dosage 15 g

    Active substance: Potassium permanganate 15.0 g.

    Description:Dark purple or red-violet crystals or a fine crystalline powder with metallic luster.
    Pharmacotherapeutic group:Antiseptic
    ATX: & nbsp

    D.08.A.X   Other antiseptics and disinfectants

    D.08.A.X.06   Potassium permanganate

    Pharmacodynamics:

    Antiseptic. When in contact with organic matter, it releases an atomic oxygen. The oxide formed in the reduction of potassium permanganate potassium oxide forms complex compounds with proteins - albumins (due to this potassium permanganate at low concentrations have astringent, and in concentrated solutions - irritating, cauterizing and tanning action). It also has a deodorizing effect. Effective in the treatment of burns and ulcers. Potassium permanganate ability to neutralize some poisons underlies the use of its solutions for washing the stomach with poisoning.

    If ingested, absorbed, having a hematotoxic effect (leads to the development of methemoglobinemia).

    The drug belongs to the list of IV precursors subject to control in the Russian Federation.
    Indications:

    Lubrication of ulcerous and burn surfaces - infected wounds, ulcers and skin burns.

    Rinsing of the mouth and throat with infectious and inflammatory diseases of the mucous membrane of the mouth (including with tonsillitis).

    For rinsing and syringing with gynecological and urological diseases - colpitis and urethritis.

    For lavage - the stomach with poisoning caused by intake of alkaloids (morphine, aconitine, nicotine), hydrocyanic acid, phosphorus, quinine; skin - if you hit it with aniline; eye - when affected by poisonous insects.

    If necessary, please,consult a physician before using the medication.

    Contraindications:

    Hypersensitivity.

    Pregnancy and lactation:

    After consulting a doctor, the drug may be used if the expected benefit to the mother exceeds the potential risk to the fetus or the baby.

    Dosing and Administration:

    Outwardly, in aqueous solutions: for washing the wounds (0.1 - 0.5%),

    for lubricating ulcer and burn surfaces (2-5 %), for syringing (0,02 - 0,1%) in gynecological and urological practice, as well as gastric lavage during poisoning. Locally, to rinse the mouth and throat (0.01 - 0.1%).

    To dissolve - several crystals are placed in a glass with warm water and mixed, the solution is used only freshly prepared.

    If there is no improvement after treatment or new symptoms appear, it is necessary to consult a doctor.

    Use the drug only according to the method of administration and the doses specified in the instructions. If necessary, please consult with your doctor before using the medication.

    Side effects:

    Allergic reactions, when using concentrated solutions - burns and irritation.

    If any of the side effects listed in the manual are aggravated, or if you notice any other side effects not listed in the instructions, tell your doctor.

    Overdose:

    Symptoms: severe pain in the oral cavity, along the esophagus, in the abdomen, vomiting, diarrhea; oral mucosa and pharynx - edematous, dark brown, purple, laryngeal edema is possible, the development of mechanical asphyxia, burn shock, motor excitation, seizures, Parkinson's phenomena, hemorrhagic colitis, nephropathy, hepatopathy. With reduced acidity of gastric juice, the development of methemoglobinemia with pronounced cyanosis and dyspnea is possible. The lethal dose for children is about 3 g, for adults 0.3-0.5 g / kg.

    Treatment: ascorbic acid (in / in - 30 ml of a 5% solution), cyanocobalamin - up to 1 mg, pyridoxine (in / m - 3 ml of 5% solution).

    Interaction:Not chemically compatible with some organic substances (charcoal, sugar, tannin) and easily oxidizable substances - an explosion can occur.
    Effect on the ability to drive transp. cf. and fur:The drug does not affect the ability to drive vehicles or engage in other potentially hazardous activities that require increased concentration and speed of psychomotor reactions.
    Form release / dosage:

    Powder for solution for local and external use.

    Packaging:

    By 3, 5 or 15 g of the drug in bottles made of glass or polymeric bottles from low-pressure polyethylene grade 276-73, sealed with a polymer stopper from low-pressure polyethylene grade 276-73 or a lid of a pressure-tightened polymer with a first opening or a stopper 276-73 with a shovel.

    By 3, 5 or 15 g of the drug in glass bottles with a screw mouth, sealed with plastic caps screwed on or plastic caps screwed on with blades.

    By 3, 5 or 15 g of the drug in bags of polyethylene film.

    On labels and packs stick labels self-adhesive. Each vial, a package with instructions for use is placed in a pack of cardboard.

    By 2, 3, 5, or 10 packs together with the instruction for use are placed in a pack of cardboard.

    50, 75, 100, 150, 200 vials or bags are placed together with an equal number of instructions for use in a group package of cardboard (for hospitals).

    50, 75, 100, 150, 200 bags are placed in bags of multilayer polymer film together with an equal number of instructions for use (for hospitals).

    Storage conditions:

    List of IV precursors.

    In a dry place, at a temperature of no higher than 25 ° C. Keep out of the reach of children!

    Shelf life:

    5 years. Do not use after the date indicated on the package.

    Terms of leave from pharmacies:Without recipe
    Registration number:LP-004059
    Date of registration:29.12.2016
    Expiration Date:29.12.2021
    The owner of the registration certificate:LEKAR, LLC LEKAR, LLC Russia
    Manufacturer: & nbsp
    Information update date: & nbsp26.01.2017
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