Streptocide - instructions for use, dose, side effects, contraindications

Pharmacodynamics:Streptocide is an antimicrobial bacteriostatic agent. The mechanism of action is due to competitive antagonism with para-aminobenzoic acid (PABA) and inhibition of dihydropteroate synthetase, which leads to a disruption in the synthesis of dihydrofolic and then tetrahydrofolic acid and, as a result, a violation of the synthesis of nucleic acids of microorganisms. Activity is manifested in gram-positive and gram-negative microorganisms: Escherichia coli, Shigella spp., Vibrio cholerae, Clostridium perfringens, Bacillus anthracis, Corynebacterium diphtheriae, Yersinia pestis, Chlamydia spp., Actinomyces israelii, Toxoplasma gondii.

Pharmacokinetics:When injected into the body streptotsid quickly absorbed. The highest concentration of the drug in the blood is created 1 to 2 hours after administration. After 4 hours, it is found in the cerebrospinal fluid. It is allocated mainly (90 - 95%) kidneys.

Indications:Streptocide is used in complex therapy for treatment of purulent wounds, infected burns and other purulent-inflammatory processes of soft tissues.

Contraindications:

Hypersensitivity to sulfonamides, pregnancy, lactation. Diseases of the hematopoietic system, oppression of bone marrow hematopoiesis, anemia, azotemia, thyrotoxicosis, chronic heart failure, renal failure, porphyria,hepatic insufficiency, congenital deficiency of glucose-6-phosphate dehydrogenase.

Dosing and Administration:Streptocide is applied to the wound in the form of a thoroughly crushed powder (5-10-15 g), if necessary, simultaneously assigning antimicrobials to the interior.

Side effects:

Allergic reactions, headache, dizziness, nausea, vomiting, dyspepsia, cyanosis, leukopenia, agranulocytosis, crystalluria are possible.

Overdose:Symptoms: nausea, vomiting, intestinal colic, dizziness, headache, drowsiness, depression, fainting, confusion, visual impairment, fever, hematuria, crystalluria; with prolonged overdose - thrombocytopenia, leukopenia, megaloblastic anemia, jaundice.

Treatment: intake of fluid inside, with accidental ingestion - gastric lavage.

Interaction:

Myelotoxic drugs increase the manifestation of hematotoxicity of the drug.

Special instructions:During therapy, an abundant alkaline drink is recommended.

Effect on the ability to drive transp. cf. and fur:

Form release / dosage:

Powder for external use.

Packaging:

2 g in heat-sealing bags of the combined material "Buflen" for the packaging of medicines, from a combined material on a paper basis with polyethylene coating, packaging material from a film of polypropylene metallized.

2, 5, 10, 20, 50, 100, 200, 600 packages, together with an equal number of instructions for use, are placed in a polyethylene hermetically sealed bag (sleeve) from a polyethylene food film, or combined on a paper and cardboard basis, or packing material from polypropylene metallized films.

Storage conditions:

List B. In a dry, the dark place at a temperature of no higher than 25 ° C.

In a place inaccessible to children.

Shelf life:

5 years.

Do not use after expiry date.

Terms of leave from pharmacies:Without recipe

Registration number:LSR-008202/09

Date of registration:16.10.2009

The owner of the registration certificate:LYUMI, LLC LYUMI, LLC Russia

Manufacturer: & nbsp

LYUMI, LLC Russia

Information update date: & nbsp29.08.2015

Illustrated instructions

Instructions

Streptocide (Streptocide)