Streptocide-LekT - instructions for use, dose, side effects, contraindications

Streptocide is an antimicrobial bacteriostatic agent. The mechanism of action is due to competitive antagonism with paraaminobenzoic acid (PABA) and competitive inhibition of the enzyme dihydropteroate synthetase. This leads to a disruption in the synthesis of dihydrofolic and then tetrahydrofolic acid and, as a result, a violation of the synthesis of nucleic acids of microorganisms.

Sulfanilamide is active against gram-positive and gram-negative microorganisms: Escherichia coli, Shigella spp., Vibrio cholerae, Clostridium spp., Bacillus anthracis, Corynebacterium diphtheriae, Yersinia pestis, as well as Chlamydia spp., Actinomyces spp., Toxoplasma gondii.

Indications:

As part of complex therapy: purulent wounds, infected burns (I-II etc.) and other purulent-inflammatory processes of the skin.

Contraindications:

Hypersensitivity to sulfonamides, hematopoietic system disease, inhibition of bone marrow hematopoiesis, anemia, chronic heart failure, hyperthyroidism, renal / hepatic insufficiency, azotemia, porphyria, congenital deficiency of glucose-6-phosphate dehydrogenase, pregnancy, breast-feeding.

Carefully:DUp to 3 years old.

Pregnancy and lactation:Contraindicated in pregnancy and during breastfeeding.

Dosing and Administration:

External, applied directly to the affected surface.

Maximum single dose for adults - 5 g, the maximum daily dose - 15 g.

For children over 3 years old: a single dose of 300 mg, a daily dose of 300 mg.

Side effects:

With hypersensitivity to sulfanilamide agents, allergic reactions are possible, the development of which requires immediate discontinuation of the drug.

In addition, there may be: headache, dizziness, nausea, vomiting, dyspepsia, cyanosis, leukopenia, agranulocytosis, crystalluria.

If any of the side effects listed in the manual are aggravated, or if you notice any other side effects not listed in the instructions, tell your doctor.

Overdose:

Symptoms: nausea, vomiting, intestinal colic, dizziness, headache, drowsiness, depression, syncope, confusion, visual impairment, fever, hematuria, crystalluria; with prolonged overdose - thrombocytopenia, leukopenia, megaloblastic anemia, jaundice.

Treatment: abundant drinking; with accidental ingestion - gastric lavage.

Interaction:

Myelotoxic drugs increase the manifestation of hematotoxicity of the drug.

Special instructions:

During therapy, an abundant alkaline drink is recommended.

When hypersensitivity reactions appear, treatment should be discontinued.

With prolonged treatment, systematic monitoring of the blood picture, kidney and liver function is recommended.

If necessary, concomitantly prescribe antimicrobials inwards.

Effect on the ability to drive transp. cf. and fur:

Studies of the effect of the drug on the reaction rate when driving vehicles or working with other mechanisms have not been carried out.

Considering the side effects of the drug (dizziness), care should be taken when driving vehicles and mechanisms.

Form release / dosage:

Powder for external use.

Packaging:

By 2.0 g or 5.0 g in heat-sealing bags of multi-ply composite or paper with a polymer-coated packaging.

10, 20, 50, 100, 300 packages are laid in a polyethylene sleeve or a pack of cardboard for consumer containers with 10, 20, 50, 100, 300 instructions for use, respectively. By 1, 2, 3, 4, 5, 10 or 20 polyethylene hoses or packs of cardboard are placed in a group package (carton box).

Or 200, 300, 500 packages in a group package (carton box) with attachment of 200, 300, 500 instructions for use (for hospitals).

Storage conditions:

Store in a dark place at a temperature of no higher than 25 ° C.

Keep out of the reach of children.

Shelf life:

5 years.

Do not use after expiry date.

Terms of leave from pharmacies:Without recipe

Registration number:LP-003596

Date of registration:04.05.2016

Expiration Date:04.05.2021

The owner of the registration certificate:PATENT-FARM, CJSC PATENT-FARM, CJSC Russia

Manufacturer: & nbsp

Tyumen Chemical - Pharmaceutical Plant, OJSC Russia

Information update date: & nbsp08.07.2016

Illustrated instructions

Instructions

Streptocide-LexT (Streptocide-LekT)