Streptocide - instructions for use, dose, side effects, contraindications

Pharmacodynamics:Streptocide is an antimicrobial bacteriostatic agent. The mechanism of action caused by competitive antagonism with paraamino-benzoic acid (PABA) and inhibition digidropteroatsintetazy, which disrupts the synthesis of dihydrofolate and then ragidrofolievoy tet-acid and as a result - to disruption synthesis of nucleic acids of microorganisms. Activity is manifested in gram-positive and gram-negative microorganisms: Escherichia coli, Shigella spp., Vibrio cholerae, Clostridium perfringens, Bacillus anthracis, Corynebacterium diphtheriae, Yersinia pestis, Chlamydia spp., Actinomyces israelii, Toxoplasma gondii.

Indications:

In the complex therapy: purulent wounds, infected burns (I-II cent.) And other purulent-inflammatory processes of soft tissues.

Contraindications:Hypersensitivity to sulfonamides, hematopoietic system disease, inhibition of bone marrow hematopoiesis, anemia, chronic heart failure, hyperthyroidism, renal / hepatic insufficiency, azotemia, porphyria, congenital deficiency of glucose-6-phosphate dehydrogenase, pregnancy, breast-feeding.

Carefully:Childhood.

Dosing and Administration:Outwardly,apply directly to the affected surface (in the form of powder for external use); Dressings are carried out after 1-2 days. The maximum single dose is 5 g, the maximum daily dose is 15 g.

Side effects:With hypersensitivity to sulfanilamide agents, local allergic reactions are possible, the development of which requires immediate discontinuation of the drug.

Overdose:

Symptoms: nausea, vomiting, intestinal colic, dizziness, headache, drowsiness, depression, fainting, confusion, visual impairment, fever, hematuria, crystalluria; with prolonged overdose - thrombocytopenia, leukopenia, megaloblastic anemia, jaundice.

Treatment: abundant drink; with accidental ingestion - gastric lavage.

Interaction:Myelotoxic drugs increase the manifestation of hematotoxicity of the drug.

Special instructions:

During therapy, an abundant alkaline drink is recommended. If necessary, concomitantly prescribe antimicrobials inwards.

The drug does not affect the ability to drive vehicles and engage in other potentially hazardous activities,requiring increased concentration of attention and speed of psychomotor reactions and good vision.

Effect on the ability to drive transp. cf. and fur:

Form release / dosage:

Powder for external use.

Packaging:

By 2.0 g or 5.0 g in heat-sealing bags of material combined on the basis of aluminum foil or in heat-sealing bags of paper with a polymer-coated packaging or from paper laminated. For 10, 20, 50 and 100 bags, together with the instructions for use, are placed in a pack of cardboard.

By 5.0 g in cans with a triangular corolla made of orange glass, sealed with polymeric stretch lids. The bank, together with the instruction for use, is placed in a pack of cardboard.

Packing for hospitals.

For 200 or 500 packets, together with an equal number of instructions for use are placed in a group package.

Storage conditions:In a dry, the dark place at a temperature of no higher than 25 C. Keep out of reach of children.

Shelf life:

5 years.

Do not use the drug after the expiration date.

Terms of leave from pharmacies:Without recipe

Registration number:LP-002732

Date of registration:28.11.2014

The owner of the registration certificate:MOSCOW PHARMACEUTICAL FACTORY, CJSC MOSCOW PHARMACEUTICAL FACTORY, CJSC Russia

Manufacturer: & nbsp

MOSCOW PHARMACEUTICAL FACTORY, CJSC Russia

Information update date: & nbsp29.08.2015

Illustrated instructions

Instructions

Streptocide (Streptocide)