Active substanceSulfanilamideSulfanilamide
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  • Dosage form: & nbspPowder for external use.
    Composition:Active substance - sulfonamide 5.0 g.
    Description:White crystalline powder odorless.
    Pharmacotherapeutic group:Antimicrobial agent, sulfonamide.
    ATX: & nbsp

    D.06.B.A   Sulfonamides

    Pharmacodynamics:Streptocide is an antimicrobial bacteriostatic agent. The mechanism of action is due to competitive antagonism with para-aminobenzoic acid (PABA) and inhibition of dihydropteroate synthetase, which leads to a disruption in the synthesis of dihydrofolic and then tetrahydrofolic acid and, as a result, a violation of the synthesis of nucleic acids of microorganisms. Activity manifests itself in the relationship of gram-positive and gram-negative microorganisms.
    Indications:Streptocide is used in complex therapy for treatment of purulent wounds, infected burns and other purulent-inflammatory processes of soft tissues.
    Contraindications:
    Hypersensitivity to sulfonamides. Pregnancy, lactation.
    Diseases of the hematopoietic system, oppression of bone marrow hematopoiesis, anemia, thyrotoxicosis, chronic heart failure, renal failure, porphyria, hepatic insufficiency, congenital deficiency of lucose-6-phosphate dehydrogenase.
    Dosing and Administration:Streptocide is applied to the wound in the form of a thoroughly crushed powder (5-10-15 g), if necessary, simultaneously assigning antimicrobials to the interior.
    Side effects:Allergic reactions, headache, dizziness, nausea, vomiting, cyanosis, leukopenia, agranulocytosis, crystalluria are possible.
    Overdose:Symptoms: nausea, vomiting, intestinal colic, dizziness, drowsiness, depression, fainting, confusion, visual impairment, fever, hematuria, crystalluria; with prolonged overdose of thrombocytopenia, leukopenia, megaloblastic anemia, jaundice. Treatment: plentiful drink; with accidental ingestion - gastric lavage.
    Interaction:Myelotoxic drugs increase the manifestation of hematotoxicity of the drug.
    Special instructions:During therapy, an abundant alkaline drink is recommended.
    Form release / dosage:Powder for external use.
    Packaging:For 5 g in heat-sealing bags or glass bottles. Vial with instructions for use or 3 packages with instructions for use in a pack of cardboard or without a pack.
    Storage conditions:List B. In a dry, dark place, out of reach of children, at a temperature not exceeding + 30 ° C.
    Shelf life:
    5 years.
    Do not use after the expiration date.
    Terms of leave from pharmacies:Without recipe
    Registration number:LSR-001059/08
    Date of registration:26.02.2008
    The owner of the registration certificate:YAROSLAVSK PHARMACEUTICAL FACTORY, CJSC YAROSLAVSK PHARMACEUTICAL FACTORY, CJSC Russia
    Manufacturer: & nbsp
    Information update date: & nbsp29.08.2015
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