Active substanceSulfanilamideSulfanilamide
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  • Dosage form: & nbsppowder for external use
    Composition:Active substance: Sulfanilamide 2.0 g, 5.0 g, 10.0 g.
    Description:White crystalline powder, odorless.
    Pharmacotherapeutic group:Antimicrobial agent - sulfonamide.
    ATX: & nbsp

    D.06.B.A   Sulfonamides

    Pharmacodynamics:Streptocide is an antimicrobial bacteriostatic agent, sulfanilamide. The mechanism of action is due to competitive antagonism with paraaminobenzoic acid (PANC), inhibition of dihydropteroate synthase, a violation of the synthesis of tetrahydrofolic acid, necessary for the synthesis of purines and pyrimidipes. It is active against gram-positive and gram-negative cocci, Escherichia coli. Shigella spp., Vibrio cholerae, Clostridium perfringens, Bacillus anthracis, Corynebacterium diphtheriae, Yersinia pestis. Chlamydia spp., Actinomyces israelii. Toxoplasma gondii. When applied to the skin, it contributes to the rapid healing of wounds and epithelialization of erosion.
    Indications:In the complex therapy: purulent wounds, infected burns (I-II degrees) and other purulent-inflammatory processes of soft tissues.
    Contraindications:
    - hypersensitivity to sulfonamides;
    - hepatic or renal insufficiency;
    - diseases of the hematopoietic system;
    - oppression of bone marrow hematopoiesis;
    - anemia;
    - chronic heart failure;
    - congenital deficiency of glucose-6-phosphate dehydrogenase;
    - azotemia;
    - porphyria;
    - thyrotoxicosis;
    - pregnancy and the period of breastfeeding.
    Carefully:Childhood.
    Pregnancy and lactation:The drug is contraindicated in pregnancy and during breastfeeding.
    Dosing and Administration:
    External, applied directly to the affected surface (in the form of powder for external use). Dressings are produced after 1-2 days. Maximum doses for adults: single dose - 5 g, daily dose - 15 g. Children older than 3 years - 300 mg - single dose, daily dose of 300 mg.
    Side effects:
    With hypersensitivity to sulfanilamide drugs, allergic reactions are possible, the development of which requires immediate discontinuation of the drug. In addition, headache, dizziness, nausea, vomiting, dyspepsia, cyanosis, leukopenia, agranulocytosis, crystalluria are possible. If any of the side effects listed in the manual are aggravated, or if you notice any other side effects not listed in the instructions, tell your doctor.
    Overdose:Symptoms: nausea, vomiting, intestinal colic, dizziness, headache, drowsiness, depression, fainting, confusion, visual impairment, fever, hematuria, crystalluria; with prolonged overdose - thrombocytopenia, leukopenia, megaloblastic anemia, jaundice.
    Treatment: abundant drink; with accidental ingestion - gastric lavage.
    Interaction:Myelotoxic drugs increase the manifestation of hematotoxicity of the drug.
    Special instructions:During therapy, an abundant alkaline drink is recommended. If necessary, prescribe antimicrobial drugs inside.
    Effect on the ability to drive transp. cf. and fur:Given the side effects of the drug should be careful when driving vehicles, mechanisms.
    Form release / dosage:Powder for external use.
    Packaging:
    2 g or 5 grams in a heat-sealable bag of packaging material combined on the basis of aluminum foil, of combined paper-based material, of composite film materials.
    For 1, 3, 5, 10, 20 heat-sealable bags, together with instructions for use, are placed in a cardboard pack.
    For 50, 100, 200, 300, 500 heat-sealable packages, together with an equal number of instructions for use, are placed in a polyethylene film bag with a polyethylene food or cardboard box (for hospitals).
    According to g, 5 g or 10 g in a polymer tube, corked with a polymer stopper or in a glass bottle, sealed with a rubber stopper and an aluminum cap.For 10, 20 test tubes or vials, together with the instruction for use, is placed in a cardboard patch.
    For 50, 100, 200, 300, 500 test tubes or vials with an equal number of instructions for use in a cardboard box (for hospitals).
    For 10 g in a can of polymer with a dispenser. The bank, together with the instruction for use, is placed in a pack of cardboard.
    Storage conditions:In a dry, protected from light place at a temperature of no higher than 25 ° C. Keep out of the reach of children.
    Shelf life:5 years. Do not use after expiry date.
    Terms of leave from pharmacies:Without recipe
    Registration number:LP-003112
    Date of registration:23.07.2015
    The owner of the registration certificate:LEKAR, LLC LEKAR, LLC Russia
    Manufacturer: & nbsp
    Information update date: & nbsp29.08.2015
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