Streptocide - instructions for use, dose, side effects, contraindications

Streptocide is an antimicrobial bacteriostatic agent. The mechanism of action is due to competitive antagonism with para-aminobenzoic acid (PABA) and inhibition of dihydropteroate synthetase, which leads to a disruption in the synthesis of dihydrofolic and then tetrahydrofolic acid and, as a result, a violation of the synthesis of nucleic acids of microorganisms. Activity is manifested in gram-positive and gram-negative microorganisms: Escherichia coli, Shigella spp., Vibrio cholerae, Clostridium perfringens, Bacillus anthracis, Corynebacterium diphtheriae, Yersinia pestis, Chlamydia spp., Actinomyces israelii, Toxoplasma gondii.

Indications:

As part of complex therapy: purulent wounds, infected burns (I - II degree) and other purulent-inflammatory processes of the skin.

Contraindications:

-Increased sensitivity to sulfonamides;

-heating of the hematopoietic system;

-prevention of bone marrow hematopoiesis;

-anemia;

-chronic heart failure;

- thyrotoxicosis;

- kidney or liver failure;

-asotemia;

-porphyria;

- Protein deficiency of glucose-6-phosphate dehydrogenase;

-Birth and the period of breastfeeding.

Carefully:

Children under 3 years.

Pregnancy and lactation:

The drug is contraindicated for use during pregnancy and during breastfeeding.

Dosing and Administration:

External, applied directly to the affected surface (in the form of powder for external use); Dressings are carried out after 1-2 days. The maximum single dose for adults is 5 g, the maximum daily dose for adults is 15 g.

For children older than 3 years: a single dose of 300 mg, a daily dose of 300 mg.

If there is no improvement after treatment, then you should see a doctor. Use the drug only according to the method of administration and the doses specified in the instructions. If necessary, please consult with your doctor before using the medication.

Side effects:

With hypersensitivity to sulfanilamide agents, local allergic reactions are possible, the development of which requires immediate discontinuation of the drug.

In addition, possible: headache, dizziness, nausea, vomiting, dyspepsia, cyanosis, leukopenia, agranulocytosis, crystalluria.

If any of the side effects indicated in the manual are aggravated, or any other side effects not indicated in the instructions were noted, inform the doctor.

Overdose:

Symptoms: nausea, vomiting, intestinal colic, dizziness, headache, drowsiness, depression, fainting, confusion, visual impairment, fever, hematuria, crystalluria; with prolonged overdose - thrombocytopenia, leukopenia, megaloblastic anemia, jaundice.

Treatment: abundant drinking; with accidental ingestion - gastric lavage.

Interaction:

Myelotoxic drugs increase the manifestation of hematotoxicity of the drug.

If you are taking other medications (including over-the-counter drugs) before using Streptocid, consult a doctor.

Special instructions:

During therapy, an abundant alkaline drink is recommended. If necessary, concomitantly prescribe antimicrobials inwards. With prolonged treatment, systematic monitoring of the blood picture, liver and kidney function is recommended.

Effect on the ability to drive transp. cf. and fur:

Studies of the drug on the reaction rate when driving vehicles or working with other mechanisms were not carried out.Considering the side effects of the drug (dizziness), care should be taken when driving vehicles and mechanisms.

Form release / dosage:

Powder for external use.

Packaging:

By 2.0 or 5.0 g in heat-sealing bags of packaging combined material.

By 1,2, 5, 10, 20, 50 or 100 bags together with the instruction for use are placed in a pack of cardboard.

For 100, 200 or 500 packages, together with an equal number of instructions for use are placed in a group package (For hospitals).

Storage conditions:

Store in a place protected from light and moisture at a temperature of no higher than 25 ° C.

Keep out of the reach of children.

Shelf life:

5 years. Do not use the drug after the expiration date.

Terms of leave from pharmacies:Without recipe

Registration number:LP-004556

Date of registration:23.11.2017

Expiration Date:23.11.2022

The owner of the registration certificate:Aromasintez, Open CompanyAromasintez, Open Company Russia

Manufacturer: & nbsp

Aromasintez, Open Company Russia

Information update date: & nbsp18.12.2017

Illustrated instructions

Instructions

Streptocide (Streptocide)