Choline alphoscerate (L-α-glycerylphosphorylcholine) is a prodrug, from which the choline precursor of acetylcholine is released by hydrolysis. The latter is an agonist of all subtypes of cholinergic receptors.
Choline alphoscerate contains 40.5% choline by weight released from. connections in the brain, head; Choline participates in the biosynthesis of acetylcholine, is the donor of the methyl groups, and participates in other plastic reactions in the body.Alphoscerate ion is metabolized to the glycerophosphate ion.
Acetylcholine directly participates in the transmission of the nerve impulse in both the central and peripheral nervous system. Glycerophosphate is included in various metabolic pathways, including participates in the synthesis of phosphatidylcholine (one of the phospholipids of cell membranes). Thus, the drug acts on the cholinergic transmission of the nerve impulse, the plasticity of the neuron membrane.
It is assumed that the drug reduces cognitive impairment in degenerative and vascular lesions of the brain (including cerebrovascular insufficiency and some forms of dementia).