Cholitilin - instructions for use, dose, side effects, contraindications

Provides the synthesis of acetylcholine and phosphatidylcholine in neuronal membranes, improves blood flow and enhances metabolic processes in the central nervous system, activates the reticular formation. Increases the linear velocity of blood flow, contributes to the normalization of spatiotemporal characteristics of spontaneous bioelectric activity of the brain, regression of focal neurological symptoms and restoration of consciousness; has a positive impacton cognitive and behavioral reactions of patients with cerebral vascular diseases (dyscirculatory encephalopathy and residual phenomena of cerebral circulation disorders). Provides a preventive and corrective effect on the pathogenetic factors of the involutionary psychoorganic syndrome, reduces cholinergic activity. Stimulates the dose-dependent release of acetylcholine under physiological conditions; participating in the synthesis of phosphatidylcholine (membrane phospholipid), improves synaptic transmission, plasticity of neuronal membranes. Has no effect on the reproductive cycle and does not have a teratogenic, mutagenic effect.

Pharmacokinetics:Choline alfoscerate easily penetrates the blood-brain barrier. It is mainly excreted in the form of light in the form of carbon dioxide (85%), as well as by the kidneys and through the intestine (15%).

Indications:In complex therapy with:

- craniocerebral trauma with predominantly stem lesion level (acute period);

- cerebrovascular insufficiency;

- psycho-organic syndrome on the background of degenerative diseases and involuntary processes of the brain;

- multi-infarct dementia.

Contraindications:

- hypersensitivity;

- hemorrhagic stroke (acute stage);

- Pregnancy;

- the period of breastfeeding;

- age to 18 years.

Dosing and Administration:The drug is administered intramuscularly at a dose of 1 g (1 ampoule) per day or intravenously slowly 1 g per day for 15-20 days. In the future, it is possible to switch to the oral form of the preparation (capsule).

Side effects:

From the digestive system: constipation, diarrhea, dryness of the oral mucosa, pharyngitis.

From the nervous system: headache, drowsiness, insomnia, aggressiveness, anxiety, nervousness, dizziness.

From the skin: rash, hives.

Other: pain at the injection site, frequency of urination.

Interaction:Drug interaction of the drug is not established.

Special instructions:During the treatment period, care must be taken when driving vehicles and engaging in other potentially hazardous activities that require increased concentration and speed of psychomotor reactions.

Form release / dosage:Solution for intravenous and intramuscular injection 250 mg / ml.

Packaging:

By 4 ml into ampoules of colorless glass of the 1 st hydrolytic class, having a break point.

By 3, 5 or 10 ampoules are placed in a contour mesh package made of a polyvinyl chloride film.

For 1 or 2 contour mesh packages along with the instruction for use are placed in a pack of cardboard.

It is allowed to put a scarifier in the pack.

Storage conditions:Store in a dry, dark place at a temperature of no higher than 25 ° C. Keep out of the reach of children.

Shelf life:

2 years.

Do not use after the expiration date.

Terms of leave from pharmacies:On prescription

Registration number:LSR-005773/10

Date of registration:23.06.2010

The owner of the registration certificate:Company DEKO, LLC Company DEKO, LLC Russia

Manufacturer: & nbsp

Company DEKO, LLC Russia

Information update date: & nbsp26.09.2015

Illustrated instructions

Instructions

Holilitil (Cholitilin)