Active substanceDimethylsulfoxideDimethylsulfoxide
Similar drugsTo uncover
  • Dimexide
    concentrate cutaneous 
  • Dimexide
    concentrate cutaneous 
  • Dimexide
    concentrate externally 
  • Dimexide
    concentrate cutaneous 
  • Dimexide
    concentrate cutaneous 
    ROSFARM, LLC     Russia
  • Dimexide
    concentrate cutaneous 
  • Dimexide
    gel externally 
    BIOFARMAKS, LLC     Russia
  • Dimexide
    concentrate externally 
    MARBIOFARM, OJSC     Russia
  • Dimexide
    concentrate cutaneous 
  • Dimexide
    concentrate cutaneous 
  • Dimexide
    concentrate externally 
  • Dimexide
    concentrate externally 
    YUZHFARM, LLC     Russia
  • Dosage form: & nbspConcentrate for the preparation of solution for external use.
    Composition:

    Active substance:

    Dimexide (dimethylsulfoxide) 50 ml or 100 ml.

    Description:Colorless transparent liquid or colorless crystals without a smell or with a weak specific odor. Hygroscopic.
    Pharmacotherapeutic group:Anti-inflammatory for topical use.
    ATX: & nbsp

    M.02.A.X.03   Dimethylsulfoxide

    G.04.B.X.13   Dimethylsulfoxide

    Pharmacodynamics:

    Anti-inflammatory drug for external use, inactivates hydroxyl radicals, improves the course of metabolic processes in the focus of inflammation. It also has local anesthetic, analgesic and antimicrobial action; has a moderate fibrinolytic activity.

    Penetrates through the skin, mucous membranes, the membrane of microbial cells (increases their sensitivity to antibiotics) and other biological membranes, increases their permeability for medicines.

    Indications:

    As part of complex therapy: diseases of the musculoskeletal system - rheumatoid arthritis, ankylosing spondylitis, deforming osteoarthritis, reactive synovitis, limited scleroderma, nodal erythema, discoid lupus erythematosus, mycosis stop, keloid scars, thrombophlebitis, alopecia, eczema, erysipelas , bruises, sprains, traumatic infiltrates, purulent wounds, burns, radiculitis, trophic ulcers, acne, furunculosis, in skin surgery - canning of skin homotransplants.

    Contraindications:

    Hypersensitivity, severe hepatic and / or renal insufficiency, stenocardia expressed arteriosclerosis, glaucoma, cataract, stroke, coma, myocardial infarction, pregnancy, lactation. Children under the age of twelve should not be appointed.

    Pregnancy and lactation:Contraindicated in pregnancy and during breastfeeding.
    Dosing and Administration:

    Nakozhno, in the form of appliqués and irrigation (washing). In solution of the required concentration, gauze wipes are moistened and applied to the affected areas within 20-30 minutes. A polyethylene film and cotton or linen cloth are applied over the napkin. The recommended period of use of applications is 10-15 days.

    When treating erysipelas and trophic ulcers - in the form of 30-50% solution of 50-100 ml 2-3 times a day.

    With eczema - compresses with 40-90% solution.

    For local anesthesia with pain syndromes - 25-50% solution in the form of compresses of 100-150 ml 2-3 times a day.

    10-20-30% solutions are used for facial skin and other highly sensitive areas.

    In the surgery used kozhnoplasticheskoy dressings with 20-30% solution in transplanted skin homografts auto- and directly after surgery and on the following days postoperative resistant to engraftment.

    As preserving medium for storage of skin homotransplants, 5% solution is used in Ringer's solution.

    Less concentrated solutions produce washing of purulent necrotic and inflammatory foci and cavities.

    Side effects:Allergic reactions, contact dermatitis, erythema, dry skin, mild burning, itchy dermatitis, rarely - bronchospasm.
    Interaction:

    Compatible with heparin, antibacterial agents, NSAIDs. It increases the sensitivity of microorganisms to aminoglycoside and beta-lactam antibiotics, chloramphenicol, rifampin, griseofulvin.

    Special instructions:Some patients feel the smell of garlic in the inspired air.

    Before using the drug, it is necessary to carry out a test for tolerance to it. For this dimethylsulfoxide apply to the skin with a cotton swab soaked in it; the appearance of hyperemia and pronounced itching indicates a hypersensitivity.

    Effect on the ability to drive transp. cf. and fur:The use of the drug in accordance with the instruction does not affect the management of vehicles and occupations of potentially hazardous activities requiring increased concentration of attention and speed of psychomotor reactions.
    Form release / dosage:Concentrate for the preparation of solution for external use 99%.
    Packaging:

    To 50 ml or 100 ml in bottles of orange glass, or in vials polymeric, or in bottles from high or low pressure polyethylene. Each bottle, together with the instructions for use, is placed in a pack of cardboard. Only for hospitals it is allowed to pack 50 ml bottles in an amount of 70 pieces and 100 ml in an amount of 50 pieces in a group package (carton box) with an equal number of instructions for use.

    For bottles, packs and each unit of consumer packaging glue a self-adhesive label.

    For 5 kg of the drug in cans of high-pressure polyethylene unstabilized and unpainted (for hospitals).

    Each canister should be accompanied by instructions for the use of the drug, placed in a bag of polyethylene.

    Storage conditions:

    In a dry, protected from light place at a temperature of no higher than 25 ° C. Keep out of the reach of children.

    Shelf life:

    2 years.

    Do not use after expiry date.

    Terms of leave from pharmacies:Without recipe
    Registration number:LP-002676
    Date of registration:24.10.2014
    The owner of the registration certificate:IODINE TECHNOLOGIES AND MARKETING, LTD. IODINE TECHNOLOGIES AND MARKETING, LTD. Russia
    Manufacturer: & nbsp
    Representation: & nbspIODINE TECHNOLOGIES AND MARKETING, LTD.IODINE TECHNOLOGIES AND MARKETING, LTD.
    Information update date: & nbsp05.01.16
    Illustrated instructions
      Instructions
      Up