Included in the formulation
АТХ:M.02.A.X.03 Dimethylsulfoxide
G.04.B.X.13 Dimethylsulfoxide
Pharmacodynamics:A local anti-inflammatory drug.
It has local anesthetic, local anti-inflammatory, antimicrobial (antiseptic) and fibrinolytic action. Quickly and well penetrates through biological membranes, including through the skin and mucous membranes, increases their permeability for other drugs. Changes the sensitivity of microflora, resistant to antibiotics.In most cases, they are used in combination with other medicinal substances (previously dissolved in it or applied to the skin) for better and deeper penetration into tissues (for example, with heparin in the treatment of thrombophlebitis, with glucocorticoids in the treatment of eczema, with antimicrobials in the treatment furunculosis, erysipelas, acne and others).
Pharmacokinetics:Not described.
Indications:Rheumatoid arthritis, Bechterew's disease, deforming osteoarthritis, reactive synovitis, sciatica, scleroderma, erythema nodosum, discoid lupus erythematosus, erysipelatous inflammation; bruises, sprains, inflammatory swelling; infiltrates (including traumatic); purulent wounds, burns, trophic ulcers, thrombophlebitis, eczema, acne, pustular skin diseases (pyoderma, furunculosis - as part of complex therapy); in skin and plastic surgery - preservation of skin homotransplants; in stomatology - inflammatory diseases of the maxillofacial region, salivary glands, periodontitis, pulpitis, periodontitis, arthritis and arthrosis of the temporomandibular joint.
I.A30-A49.A46 Erys
IX.I80-I89.I80.9 Phlebitis and thrombophlebitis of unspecified site
XI.K00-K14.K04.0 Pulpitis
XI.K00-K14.K05 Gingivitis and periodontal disease
XII.L00-L08.L02 Abscess of skin, boil and carbuncle
XII.L60-L75.L70 Acne
XII.L50-L54.L52 Erythema nodosum
XII.L80-L99.L93.0 Discoid lupus erythematosus
XII.L80-L99.L98.4 Chronic skin ulcer, not elsewhere classified
XIX.T08-T14.T14.0 Superficial injury of unspecified area of the body
Contraindications:Hypersensitivity, severe hepatic and / or renal failure, myocardial infarction, stenocardia, severe atherosclerosis, glaucoma, cataract, stroke, coma, pregnancy, breast-feeding.
Carefully:When allergic reactions occur, it is necessary to prescribe antihistamines.
Pregnancy and lactation:The action category for the fetus is FDA-C. Do not use in pregnancy and lactation.
Dosing and Administration:Nakozhno (in the form of applications). In a solution of the appropriate concentration (usually 50% solution, and for the skin of the face and other highly sensitive areas of the skin - 10-30% solution), moisten the napkins that are applied to the affected area for 10-30 minutes 1 time per day; Napkins are covered with a polyethylene film, and on top - with cotton or linen cloth. The course of treatment - 10-15 procedures.
Side effects:Itching dermatitis, skin rashes, dry skin, mild burning, itching; rarely - bronchospasm.
Overdose:With prolonged contact with the skin, burns, itching and burning of the affected area may occur. Treatment is symptomatic. Stop the therapy with the drug.
Interaction:Do not use simultaneously with other external means.
Special instructions:For the purpose of assessing individual tolerability, it is recommended to perform a drug test, for which a solution of the drug is applied to the skin with a cotton swab. The appearance of sharp reddening and itching indicates a heightened sensitivity.
Some patients do not tolerate the smell of the drug (nausea, vomiting are possible).