Active substanceInosineInosine
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  • Dosage form: & nbspfilm-coated tablets
    Composition:

    1 the tablet contains:

    as an active substance: inosine (riboxin) 200 mg;

    auxiliary substances: core: sucrose (sugar), potato starch, hypromellose (hydroxypropylmethylcellulose), stearic acid;

    shell: Opadrai II (series 85): polyvinyl alcohol, partially hydrolysed, talc, macrogol (polyethylene glycol 3350), titanium dioxide, iron oxide dye oxide, aluminum lacquer based on yellow quinoline, aluminum lacquer based on indigo carmine.

    Description:

    The tablets covered with a film cover, from light yellow to yellow-orange color, round, biconcave.

    Pharmacotherapeutic group:metabolic
    ATX: & nbsp

    C.01.E.B   Other drugs for the treatment of heart disease

    Pharmacodynamics:

    Refers to a group of drugs that regulate metabolic processes. Purine derivative (nucleoside), the precursor of adenosine triphosphate.

    Stimulates the synthesis of nucleotides, enhances the activity of certain enzymes of the Krebs cycle. Penetrating into cells, increases the energy level, has a positive effect on the processes of metabolism in the myocardium.

    Pharmacokinetics:

    It is well absorbed in the gastrointestinal tract. Metabolised in the liver with the formation of glucuronic acid and its subsequent oxidation. In an insignificant amount excreted in the urine.

    Indications:

    Assign adults in the complex therapy of coronary heart disease, myocardial dystrophy, after myocardial infarction,heart rhythm disorders due to the use of cardiac glycosides.

    Assign with hepatitis, cirrhosis, fatty liver, caused by alcohol or drugs and urocoppororphy.

    Contraindications:

    Hypersensitivity, gout, hyperuricemia.

    Carefully:Renal failure.
    Dosing and Administration:

    Assign inside before eating.

    The daily intake for oral administration is 0.6-2.4 g. In the first days of treatment, the daily dose is 0.6-0.8 g (0.2 g 3-4 times a day). In case of good tolerance, the dose is increased (2-3 days) by 1.2 g (0.4 g 3 times a day), if necessary - up to 2.4 g per day. The duration of the course is from 4 weeks to 1.5-3 months.

    With urocoppororphy, the daily dose is 0.8 g (0.2 g 4 times a day). The drug is taken daily for 1-3 months.

    Side effects:

    Allergic reactions are possible in the form of hives, itchy skin, skin hyperemia (drug withdrawal is required).

    Rarely with the treatment of the drug raises the concentration of uric acid in the blood and exacerbation of gout (with prolonged use).

    Form release / dosage:

    Tablets, film-coated, 200 mg.

    Packaging:

    10 tablets per contour cell pack.

    For 50 tablets in a bank of light-protective glass or a polymer canister or in a polymeric medical vial.

    Each jar or bottle, or 5 contour mesh packages together with the instruction for use, is placed in a pack of cardboard.

    Storage conditions:

    In a dry, the dark place at a temperature of no higher than 25 ° C.

    Keep out of the reach of children.

    Shelf life:

    3 years.

    Do not use after the expiration date.

    Terms of leave from pharmacies:On prescription
    Registration number:P N001524 / 01
    Date of registration:23.06.2008
    The owner of the registration certificate:NORTH STAR, CJSC NORTH STAR, CJSC Russia
    Manufacturer: & nbsp
    Representation: & nbspNORTH STAR CJSC NORTH STAR CJSC Russia
    Information update date: & nbsp23.10.2015
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