Active substanceNaphazolineNaphazoline
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  • Dosage form: & nbspnasal drops
    Composition:

    1 ml of the solution contains, as active ingredient:

    Naphthyzine (naphazolin) 0.5 mg or 1 mg.

    Excipients: boric acid - 20 mg, purified water - up to 1 ml.

    Description:

    Transparent, colorless or slightly colored liquid.

    Pharmacotherapeutic group:Antitussive medication - alpha-adrenomimetic
    ATX: & nbsp

    A.01.A.A.08   Naphazoline

    Pharmacodynamics:

    Naphthyzine has a rapid, pronounced and prolonged vasoconstrictive action against the vessels of the mucous membrane of the nasal cavity (reduces swelling, flushing, exudation). Relieves nasal breathing in rhinitis. After 5-7 days there is tolerance.

    Indications:

    Acute rhinitis, allergic rhinitis, sinusitis, eustachitis, to facilitate the conduct of a rhinoscopy.

    Contraindications:

    Hypersensitivity to the drug components, hypertension, severe atherosclerosis, hyperthyroidism, chronic rhinitis, severe eye diseases, diabetes mellitus; tachycardia; simultaneous administration of monoamine oxidase inhibitors and a period of up to 14 days after completion of theirapplication, age under 18 years (for 0.1% solution), age up to 1 year (for 0.05% solution).

    Pregnancy and lactation:

    Use during pregnancy and during breastfeeding is possible only if the expected benefit to the mother exceeds the potential risk to the fetus or child. It is necessary to consult a doctor.

    Dosing and Administration:

    In otorhinolaryngology: intranasal (in each nasal passage), adults are prescribed 1-3 drops of 0.05-0.1% solution 3-4 times a day.

    Children use 0.05% solution: from 1 to 6 years - 1-2 drops, from 6 to 15 years - 2 drops 1-3 times a day.

    For diagnostic purposes - after cleaning the nose in each nasal drip 3-4 drops or insert a swab soaked in a 0.05% aqueous solution and leave for 1-2 minutes.

    Side effects:

    Nausea, tachycardia, headache, increased blood pressure, reactive hyperemia, swelling of the nasal mucosa. Irritation of the mucous membrane of the nasal cavity, when applied for more than 1 week - swelling of the mucous membrane of the nasal cavity, atrophic rhinitis.

    Overdose:

    Symptoms: decrease in body temperature, bradycardia, increased blood pressure.

    Treatment: symptomatic.

    Interaction:

    Do not use simultaneously with monoamine oxidase inhibitors or within 14 days after the end of their use.

    Slows the absorption of local anesthetic drugs (lengthens their action in the conduct of surface anesthesia).

    Special instructions:

    May have a resorptive effect.

    The drug solution can be sterilized (after removing the drip plug and gasket) in a saturated water vapor at a temperature of 115-116 ° C for 30 minutes.

    With prolonged use, the severity of the vasoconstrictor effect gradually decreases (the phenomenon of tachyphylaxis), and in this connection it is recommended to take a break for several days after 5-7 days of use.

    The drug has no effect on the ability to perform potentially hazardous activities requiring increased concentration of attention and speed of psychomotor reactions (including driving, working with moving mechanisms).

    Form release / dosage:Nasal drops 0.05% and 0.1%.
    Packaging:

    For 10 ml in glass bottles, corked with rubber stoppers and crimped with aluminum caps, 15 ml each in polymer drop bottles or 20 ml in polymer bottles,sealed with dispensers and screwed polymer caps.

    For 1 bottle or 1 bottle-dropper with instructions for use in a pack of cardboard.

    It is allowed to pack glass bottles of 10 ml of 50 bottles each, 15 ml dropper bottles of 135 bottles or 20 ml bottles of 77 pieces each with an equal number of instructions for use in boxes or boxes of cardboard.

    For 5 or 10 ml in the bottle-dropper polymer, ukuporennyh caps or caps polymer.

    For 1 or 2 bottles of a dropper with instructions for the use of the drug in a pack of cardboard.

    By 1.3 ml, 1.5 ml, 2 ml or 5 ml in a tube-dropper polymer. By 1, 2, 4, 5 or 10 tubes with IV instructions for use in a pack of cardboard.

    In the case of the production of a medicinal product on the production site of Kirov Pharmaceutical Factory JSC.

    10 ml in bottles of glass with a capacity of 10 ml, corked with rubber stoppers, and crimped with aluminum caps.

    For 5 ml, 10 ml, 15 ml or 20 ml in bottles-droppers polyethylene, capped with caps or caps polyethylene.

    1 glass bottle of 10 ml, 1 vial of a dropper of 5 ml, or 10 ml, or 15 ml or 20 ml with instructions for use are placed in a pack of cardboard.It is allowed to pack 5 or 10 ml or 10 ml, or 15 ml or 20 ml bottles of 50 or 200 bottles with an equal number of instructions for use in carton boxes or boxes of corrugated cardboard (for hospitals) .

    Storage conditions:

    Keep in a dark place. Protect from freezing. Keep out of the reach of children.

    Shelf life:3 years. Do not use after the expiration date printed on the package.
    Terms of leave from pharmacies:Without recipe
    Registration number:LS-002047
    Date of registration:05.12.2011 / 07.10.2016
    Expiration Date:Unlimited
    The owner of the registration certificate:ALVILS, LTD. ALVILS, LTD. Russia
    Manufacturer: & nbsp
    Information update date: & nbsp16.06.2018
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