Naphthyzine - instructions for use, dose, side effects, contraindications

Alpha-adrenostimulating agent, has a rapid, pronounced and prolonged vasoconstrictive action against the vessels of the mucous membranes of the nasal cavity, nasopharynx and paranasal sinuses - reduces swelling, hyperemia, exudation, which improves nasal passages and facilitates nasal breathing. Along with this, the patency of eustachian tubes is restored.

The therapeutic effect occurs, as a rule, within 5 minutes after the administration of the drug and persists for 4-6 hours.

After 5-7 days there is tolerance.

Pharmacokinetics:With topical application, systemic absorption is low. The vasoconstrictive effect comes in a few minutes and lasts for several hours.

Indications:

Acute rhinitis (including acute respiratory diseases and allergic rhinitis), sinusitis, eustachiitis, laryngitis, laryngeal edema of allergic genesis, laryngeal edema on the background of irradiation, hyperemia of the mucosa after operations on the upper respiratory tract. To stop nasal bleeding.

To facilitate the conduct of a rhinoscopy.

Contraindications:

- Hypersensitivity to the components of the drug,

- arterial hypertension,

- severe atherosclerosis,

- thyrotoxicosis,

- an angle-closure glaucoma,

- chronic rhinitis,

- Atrophic rhinitis,

- Children under the age of 15 years,

- diabetes,

- tachycardia,

- severe eye diseases,

- simultaneous administration of monoamine oxidase inhibitors and a period of 14 days after the end of their use.

Carefully:Ischemic heart disease (angina pectoris), prostatic hyperplasia, pheochromocytoma.

Pregnancy and lactation:Use during pregnancy and during breastfeeding is possible only if the expected benefit to the mother exceeds the potential risk to the fetus or child.

Dosing and Administration:

Intranasally (in each nasal passage), adults and children over 15 years of age are prescribed 1-3 injections 3-4 times a day. Immediately after injection, it is recommended to breathe a slight sigh.

For diagnostic purposes: after cleaning the nose in each nasal pass, inject once or insert a swab dipped in the solution of the drug and leave for 1-2 minutes. Apply for a short time, but not more than 1 week. If nasal breathing is facilitated, then the use of Naphthyzine can be completed sooner. Repeated use of the drug is possible in a few days.

When using spray sprayer should be kept vertically, tip up. Holding the head straight, insert the tip into the nasal passage, once with a short movement squeeze the nebulizer, and, taking the tip out of the nose, unclench. Before the administration of the drug should be thoroughly cleaned nasal passages.

Side effects:

Nausea, tachycardia, headache, increased blood pressure, reactive hyperemia, swelling of the nasal mucosa. Irritation, when applied for more than 1 week - swelling of the nasal mucosa, atrophic rhinitis.

Overdose:Symptoms: decrease in temperature, body, bradycardia, increased blood pressure. Treatment: symptomatic.

Interaction:

Do not use simultaneously with monoamine oxidase inhibitors or during 14 days after the end of their application. Slows the absorption of local anesthetic drugs (lengthens their action in the conduct of surface anesthesia).

Special instructions:

May have a resorptive effect.

With prolonged use, the severity of the vasoconstrictor effect gradually decreases (the phenomenon of tachyphylaxis), in connection with which it is recommended after 5-7 days of use to take a break for several days.

In view of the possible development of side effects from the cardiovascular and nervous systems, do not exceed the dose of Naphthysin recommended for use. Avoid contact with the eyes. To avoid the spread of infection, it is necessary to apply the drug individually.

Effect on the ability to drive transp. cf. and fur:

After a prolonged use or intake of funds from the cold, containing naphazoline, in dosages exceeding the recommended, it is impossible to exclude the general effect on the cardiovascular system and the central nervous system.In these cases, the ability to drive vehicles and moving machinery can be reduced.

Form release / dosage:

Nasal Spray 0,1%.

Packaging:

For 15 ml in polymer bottles with a spray and with a control ring of the first vskrgiya

1 bottle with instructions for use in a pack of cardboard.

Storage conditions:

Store in a dark place at a temperature of no higher than 25 ° C.

Keep out of the reach of children.

Shelf life:3 years. Do not use after the expiry date printed on the package.

Terms of leave from pharmacies:Without recipe

Registration number:LP-001140

Date of registration:08.11.2011 / 09.11.2016

Expiration Date:Unlimited

The owner of the registration certificate:LEKKO, ZAO LEKKO, ZAO Russia

Manufacturer: & nbsp

LEKKO, ZAO Russia

Information update date: & nbsp16.06.2018

Illustrated instructions

Instructions

Naphthysine (Naphthyzin)