Naphthyzine - instructions for use, dose, side effects, contraindications

alpha-adrenostimulating agent, has a rapid, pronounced and prolonged vasoconstrictive action against the vessels of the mucous membranes (reduces swelling, flushing, exudation). Relieves nasal breathing in rhinitis. After 5-7 days there is tolerance.

Pharmacokinetics:The vasoconstrictor effect occurs in a few minutes and lasts for several hours.

Indications:

acute rhinitis, allergic rhinitis, sinusitis, eustachiitis, hyperaemia of the mucosa after operations on the upper respiratory tract. To stop nasal bleeding, to facilitate the conduct of a rhinoscopy.

Contraindications:

hypersensitivity; arterial hypertension, atherosclerosis, thyrotoxicosis, children's age (up to 1 year), chronic rhinitis, eye diseases, diabetes mellitus; simultaneous administration of monoamine oxidase inhibitors and a period of up to 14 days after the end of their use.

Carefully:

pregnancy, lactation.

Pregnancy and lactation:Carefully.

Dosing and Administration:

Dosing and Administration: intranazapno (in each nasal passage), adults are prescribed 1-3 drops of 0.05-0.1% solution 3-4 times a day. Children use 0.05% aqueous solution (or 0.025% solution, diluting 0.05% solution with distilled water): from 1 to 6 years - 1-2 drops, from 6 to 15 years - 2 drops 1-3 times a day. For diagnostic purposes - after cleaning the nose in
each nasal drip to drip 3-4 drops or insert a tampon, soaked in a 0.05% aqueous solution, and leave for 1-2 minutes; with bleeding - tampons, moistened with 0.05% solution.

Side effects:

nausea, tachycardia, headache, increased arterial pressure, reactive hyperemia, swelling of the nasal mucosa. Irritation, when applied for more than 1 week - swelling of the nasal mucosa, atrophic rhinitis.

Overdose:symptoms: decreased body temperature, bradycardia, increased blood pressure. Treatment: symptomatic.

Interaction:

should not be used simultaneously with monoamine oxidase inhibitors or within 14 days after end of their application. Slows suction local anesthetic drugs (lengthens their effect in carrying out surface anesthesia).

Special instructions:

may have a resorptive effect. The drug solution can be sterilized (after removing the drip plug and gasket) in a saturated water vapor at a temperature of 115-116 ° C for 30 minutes. With prolonged use, the severity of the vasoconstrictor effect gradually decreases (the phenomenon of tachyphylaxis), and in this connection it is recommended to take a break for several days after 5-7 days of use.

Form release / dosage:

Nasal drops, 0.05% and 0.1%.

Packaging:

For 10 ml in glass bottles, ukuporennyh stoppers rubber, crimped with aluminum caps. By 10, 15, 20 ml in polyethylene or polypropylene bottles, sealed with droppers and screw caps made of polymer material. 1 glass bottle with a lid-dropper or 1 bottle of polymer material together with the instruction for use is placed in a pack.

50 bottles of glass or polymer and 10 instructions for use are placed in a box of cardboard box (for hospitals).

Storage conditions:

in a dark place at a temperature of no higher than 25 ° C. Protect from freezing. In a place inaccessible to children.

Shelf life:3 years. Do not use after the expiration date.

Terms of leave from pharmacies:Without recipe

Registration number:LSR-003495/09

Date of registration:08.05.2009

The owner of the registration certificate:ALVILS, LTD. ALVILS, LTD. Russia

Manufacturer: & nbsp

DOBROMED, LLC Russia

Information update date: & nbsp31.07.2015

Illustrated instructions

Instructions

Naphthysine (Naphthyzin)