Active substanceNaphazolineNaphazoline
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  • Dosage form: & nbspnasal drops
    Composition:

    1 ml of the solution contains, as active ingredient:

    Naphazoline nitrate (naphthyzine) 0.5 mg or 1 mg.

    Excipients: boric acid, purified water.

    Description:

    Transparent colorless or slightly colored liquid.

    Pharmacotherapeutic group:Antitussive medication - alpha-adrenomimetic
    ATX: & nbsp

    A.01.A.A.08   Naphazoline

    Pharmacodynamics:

    Naphthyzine has a rapid, pronounced and prolonged vasoconstrictive action against the vessels of the mucous membranes (reduces swelling, flushing, exudation). Relieves nasal breathing in rhinitis. After 5-7 days there is tolerance.

    Indications:

    Acute rhinitis, allergic rhinitis, sinusitis, eustachitis, laryngitis, laryngeal edema of the larynx, laryngeal edema on the background of irradiation, hyperemia of the mucous membrane after operations on the upper respiratory tract, chronic conjunctivitis, as an auxiliary drug - with conjunctivitis of bacterial origin.

    To stop nasal bleeding, to facilitate the conduct of a rhinoscopy, to lengthen the action of local anesthetics (used for superficial anesthesia).

    Contraindications:

    Hypersensitivity to the components of the drug; arterial hypertension, severe atherosclerosis, hyperthyroidism, chronic rhinitis, severe eye diseases, diabetes mellitus; tachycardia; simultaneous administration of MAO inhibitors and a period up to 14 days after the end of their use, age to 18 years (for 0.1% solution), age to 1 year (for 0.05% solution).

    Carefully:

    Pregnancy, lactation.

    Dosing and Administration:

    In otorhinolaryngology: intranasal (in each nasal passage), adults are prescribed 1-3 drops of 0.05-0.1% solution 3-4 times a day.

    Children use 0.05% solution: from 1 to 6 years - 1-2 drops, from 6 to 18 years - 2 drops 1-3 times a day.

    For diagnostic purposes - after cleaning the nose in each nasal drip drop 3-4 drops or insert a swab soaked in a 0.05% aqueous solution and leave for 1-2 minutes; when edema of the vocal cords, administer 1-2 ml of the solution in small doses with a laryngeal syringe; when bleeding - tampons, moistened with 0.05% solution.

    In ophthalmology: 1-2 drops of 0,05% solution in the cavity of the conjunctiva 1-3 times a day.As an additional drug for surface anesthesia - 2-4 drops 0.1 % solution of naftizine per 1 ml of local anesthetic.

    Side effects:

    Nausea, tachycardia, headache, increased blood pressure, reactive hyperemia, swelling of the nasal mucosa. Irritation, if applied more than 1 week - swelling of the nasal mucosa.

    Overdose:Symptoms: decreased body temperature, bradycardia, increased arterial pressure. Treatment: symptomatic.
    Interaction:

    Do not use simultaneously with MAO inhibitors or within 14 days after the end of their use.

    Slows the absorption of local anesthetic drugs (lengthens their action in the conduct of surface anesthesia).

    Special instructions:

    May have a resorptive effect.

    The drug solution can be sterilized (after removing the drip plug and gasket) in a saturated water vapor at a temperature of 115-116 ° C for 30 minutes.

    With prolonged use, the severity of the vasoconstrictor effect gradually decreases (the phenomenon of tachyphylaxis), and in this connection it is recommended to take a break for several days after 5-7 days of use.

    Form release / dosage:

    Nasal drops 0.05% and 0.1%.

    Packaging:5 ml or 10 ml in bottles from the glass tube, sealed with rubber medical plugs and then rolling off the aluminum caps. 5 ml or 10 ml in polyethylene or polypropylene bottles, sealed with droppers and screw caps. A bottle with a dropper (or without it) along with the instruction for use is placed in a pack of cardboard box.

    Vials with equal number of instructions for use are placed in a group package.

    Storage conditions:

    In the dark place at a temperature of no higher than 25 ° C. Keep out of the reach of children.

    Shelf life:3 years. Do not use after the expiration date printed on the package.
    Terms of leave from pharmacies:Without recipe
    Registration number:LSR-001477/09
    Date of registration:03.03.2009 / 15.10.2015
    Expiration Date:Unlimited
    The owner of the registration certificate:TATHIMFARMPREPARATY, JSC TATHIMFARMPREPARATY, JSC Russia
    Manufacturer: & nbsp
    Information update date: & nbsp17.06.2018
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