Naphthyzine - instructions for use, dose, side effects, contraindications

Active substance:
Naphazoline nitrate (naphthysine)	- 0.0005 g	- 0.001 g
Auxiliary substances:
Boric acid	- 0.02 g	- 0.02 g
Purified water	- up to 1 ml	- up to 1 ml

Description:Transparent, colorless or slightly yellowish liquid.

Pharmacotherapeutic group:Antitussive medication - alpha-adrenomimetic

ATX: & nbsp

A.01.A.A.08 Naphazoline

Pharmacodynamics:

Naphthyzine has a rapid, pronounced and prolonged vasoconstrictive action against the vessels of the mucous membrane of the nasal cavity (reduces swelling, flushing, exudation). Relieves nasal breathing in rhinitis. After 5-7 days there is tolerance.

Indications:

Acute rhinitis, allergic rhinitis, sinusitis, eustachiitis, for ease of rhinoscopy, laryngitis, laryngeal edema of allergic genesis, laryngeal edema on the background of irradiation, hyperemia of the mucosa after operations on the upper respiratory tract. To stop nasal bleeding, to extend the action of local anesthetics used for superficial anesthesia.

Contraindications:

Hypersensitivity to the drug components, arterial hypertension, severe atherosclerosis, hyperthyroidism, chronic rhinitis, atrophic rhinitis, severe eye diseases, angle-closure glaucoma, diabetes mellitus; tachycardia; simultaneous administration of monoamine oxidase inhibitors and up to 14 days after the end of their use, children under 18 years (for 0.1% solution), children under 1 year (for 0.05 % solution).

Carefully:

Ischemic heart disease (angina pectoris), prostatic hyperplasia, pheochromocytoma, pregnancy, the period of breastfeeding.

Pregnancy and lactation:

Use during pregnancy and during breastfeeding is possible only if the expected benefit to the mother exceeds the potential risk to the fetus or child. It is necessary to consult a doctor.

Dosing and Administration:

In otorhinolaryngology: intranasal (in each nasal passage).

Adults are recommended to instill 2-3 drops of 0.05% or 0.1% solution 3-4 times a day in each nasal passage.

Children use 0.05% solution: from 1 to 6 years - 1-2 drops, from 6 to 18 years - 2 drops 1-3 times a day.

For diagnostic purposes - after cleaning the nose in each nasal drip drop 3-4 drops or insert a swab moistened with 0.05% solution of the drug, and leave for 1-2 minutes.

When edema of the vocal cords, 1 to 2 ml of 0.05% solution of the drug in small doses with a laryngeal syringe; when bleeding - tampons, moistened with 0,05% solution of the preparation; as an additional drug for surface anesthesia - 2-4 drops per 1 ml of local anesthetic.

Side effects:

Nausea, tachycardia, headache, increased blood pressure, reactive hyperemia, swelling of the nasal mucosa.

Irritation of the mucous membrane of the nasal cavity, when applied for more than 1 week - swelling of the mucous membrane of the nasal cavity, atrophic rhinitis.

Overdose:

Symptoms: decrease in body temperature, bradycardia, increased blood pressure.

Treatment: symptomatic.

Interaction:

Do not use simultaneously with monoamine oxidase inhibitors or within 14 days after the end of their use.

Slows the absorption of local anesthetic drugs (lengthens their action in the conduct of surface anesthesia).

Co-administration of other vasoconstrictive drugs increases the risk of side effects.

Special instructions:

May have a resorptive effect.

With prolonged use, the severity of the vasoconstrictor effect gradually decreases (the phenomenon of tachyphylaxis), it is recommended after 5-7 days of use to take a break for several days.

Effect on the ability to drive transp. cf. and fur:

The drug does not affect the ability to perform potentially dangerous activities requiring increased concentration of attention and speed of psychomotor reactions (including driving and moving vehicles).

Form release / dosage:Nasal drops, 0.05% and 0.1%.

Packaging:

For 10, 15 ml in polymeric opaque vials, hermetically sealed with polymer caps; bottles-dropper polymer complete with caps screwed and lids-droppers; bottles of a glass tube for medicines, ukuporennyh stoppers rubber with obakkoy caps aluminum.

One bottle, a dropper, along with the instructions for use are placed in a pack of cardboard.

The full text of the instructions for use should be applied to the pack.

For 50 packs are placed in a group package of cardboard box.

For hospitals

For 50 bottles, flasks-droppers, together with an equal number of instructions for use are placed in a group package of cardboard box.

On bottles, bottles-droppers, group packing paste labels from paper label or writing, or self-adhesive labels.

Storage conditions:

In the dark place at a temperature of no higher than 25 ° C.

After opening, use within 30 days.

Keep out of the reach of children.

Shelf life:

3 years.

Do not use after the expiration date.

Terms of leave from pharmacies:Without recipe

Registration number:LP-003747

Date of registration:20.07.2016

Expiration Date:20.07.2021

The owner of the registration certificate:FLORA CAUCASUS, OJSC FLORA CAUCASUS, OJSC Russia

Manufacturer: & nbsp

FLORA CAUCASUS, OJSC Russia

Representation: & nbspFLORA CAUCASUS, OJSCFLORA CAUCASUS, OJSC

Information update date: & nbsp17.06.2018

Illustrated instructions

Instructions

Naphthysine (Naphthyzin)