Naphthyzine - instructions for use, dose, side effects, contraindications

Naphthyzine has a rapid, pronounced and prolonged vasoconstrictive action against the vessels of the mucous membrane of the nasal cavity (swelling, flushing, exudation). Relieves nasal breathing in rhinitis. After 5-7 days there is tolerance.

Pharmacokinetics:

With topical application, systemic absorption is low. The vasoconstrictive effect comes in a few minutes and lasts for several hours.

Indications:

Acute rhinitis, allergic rhinitis, sinusitis, eustachiitis, for ease of rhinoscopy, laryngitis, laryngeal edema of allergic genesis, laryngeal edema on the background of irradiation, hyperemia of the mucosa after operations on the upper respiratory tract.

To stop nasal bleeding, to lengthen the action of local anesthetics used for superficial anesthesia.

Contraindications:

Hypersensitivity to the drug components, arterial hypertension, severe atherosclerosis, hyperthyroidism, angle-closure glaucoma, chronic rhinitis, atrophic rhinitis, severe eye diseases, diabetes mellitus, tachycardia, simultaneous administration of monoamine oxidase inhibitors (MAO) and up to 14 days after the end of their use, age to 18 years (for 0.1% solution), children's age to 1 year (for 0.05% solution).

Carefully:

Ischemic heart disease (angina pectoris), prostatic hyperplasia, pheochromocytoma, pregnancy, the period of breastfeeding.

Pregnancy and lactation:

Application in pregnancy and during breastfeeding is possible if the intended benefit to the mother exceeds the potential risk to the fetus or child.

It is necessary to consult a doctor.

Dosing and Administration:

In otorhinolaryngology apply intranasal (in each nasal passage).

Adults: 1-3 drops of 0,05-0,1% solution 3-4 times a day.

Children use 0.05% solution: from 1 to 6 years - 1-2 drops, from 6 to 18 years - 2 drops 1-3 times a day.

For diagnostic purposes: after cleaning the nose in each nasal pass, drip 3-4 drops or insert a tampon moistened with 0.05% solution of the drug, and leave for 1-2 minutes.

With swelling of the vocal cords, administer 1-2 ml of 0.05% solution of the drug in small doses with a laryngeal syringe; when bleeding - tampons, moistened with 0.05% solution of the drug.

In rhinitis treatment should not exceed 5-7 days in adults and not more than 3 days in children.

Side effects:

Nausea, tachycardia, headache, increased blood pressure, reactive hyperemia, swelling of the nasal mucosa.

Local reactions, when applied for more than 1 week - irritation and swelling of the nasal mucosa, atrophic rhinitis.

If any of the side effects indicated in the manual are aggravated, or any other side effects not indicated in the instructions are noted, you should inform the doctor immediately.

Overdose:

Symptoms: decrease in body temperature, bradycardia, increased blood pressure.

Treatment: symptomatic.

Interaction:

Do not use simultaneously with MAO inhibitors or within 14 days after the end of their use.

Slows the absorption of local anesthetic drugs (lengthens their action in the conduct of surface anesthesia).

Joint use of other vasoconstrictive drugs increases the risk of side effects.

Special instructions:

May have a resorptive effect.

With prolonged use, the severity of the vasoconstrictor effect gradually decreases (the phenomenon of tachyphylaxis), and in this connection it is recommended to take a break for several days after 5-7 days of use.

Effect on the ability to drive transp. cf. and fur:

The drug does not affect the ability to drive vehicles or engage in other potentially hazardous activities that require increased concentration and speed of psychomotor reactions.

Form release / dosage:

Nasal drops, 0.05% and 0.1%.

Packaging:

For 10 ml of the drug in bottles from the glass tube for medicines, sealed with rubber stoppers and then rolling off the caps with aluminum.

For 10 or 15 ml of the drug in polymer bottles-droppers, hermetically sealed with polymer stoppers, droppers and caps screwed from high-pressure polyethylene.

Each vial or flask-dropper along with the instruction for use is placed in a pack of cardboard.

50, 100, 200, 250 bottles or flask-drip along with an equal number of instructions for use are placed in boxes or boxes of cardboard (for hospitals).

Storage conditions:

In the dark place at a temperature of no higher than 25 ° C.

Keep out of the reach of children.

Shelf life:

3 years.

Use the bottle after opening for 30 days.

Do not use after the expiration date printed on the package.

Terms of leave from pharmacies:Without recipe

Registration number:LP-003913

Date of registration:20.10.2016

Expiration Date:20.10.2021

The owner of the registration certificate:Aromasintez, Open CompanyAromasintez, Open Company Russia

Manufacturer: & nbsp

Aromasintez, Open Company Russia

Information update date: & nbsp17.06.2018

Illustrated instructions

Instructions

Naphthysine (Naphthyzin)