Active substanceNaphazolineNaphazoline
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  • Dosage form: & nbspnasal drops
    Composition:

    At 1 liter.

    Active substance:

    Naphazoline 0.5 g and 1 g

    Excipients:

    boric acid - 20 g

    purified water - up to 1 liter

    Description:

    Transparent colorless or slightly colored liquid.

    Pharmacotherapeutic group:Antitussive medication - alpha-adrenomimetic
    ATX: & nbsp

    A.01.A.A.08   Naphazoline

    Pharmacodynamics:

    Vasoconstrictor. Excites alpha1 and alpha2-adrenoreceptors, has anti-edematous action. The vasoconstrictive effect is manifested with local application on the nasal mucosa. When rhinitis facilitates nasal breathing, reducing the flow of blood to the venous sinuses.

    Pharmacokinetics:

    The vasoconstrictive effect comes in a few minutes and lasts for several hours.

    Indications:In acute rhinitis, allergic rhinitis, to facilitate rhinoscopy, to stop nasal bleeding.
    Contraindications:

    Hypersensitivity; arterial hypertension, severe atherosclerosis, thyrotoxicosis, children's age (up to 1 year), chronic rhinitis, severe eye diseases,diabetes; simultaneous administration of MAO inhibitors and a period of up to 14 days after the end of their use.

    Pregnancy and lactation:

    It is not recommended to use the drug during pregnancy. Application in the period of breastfeeding is possible if the expected benefit for the mother exceeds the potential risk for the child. It is necessary to consult a doctor.

    Dosing and Administration:

    In rhinitis, adults are prescribed 1-3 drops of 0.05% - 0.1% of the drug 3-4 times a day in each nasal passage, for children from 1 to 6 years 1-2 drops of 0.05% of the drug, children from 6 to 15 years - 2 drops 1-3 times a day.

    When nosebleeds are used tampons, moistened with 0.05% drug.

    To facilitate rhinoscopy - after cleaning the nose in each nasal drip 3-4 drops or insert a swab soaked in a 0.05% drug and leave for 1-2 minutes.

    Side effects:Nausea, tachycardia, headache, increased blood pressure, reactive hyperemia, swelling of the nasal mucosa. Irritation, when applied for more than 1 week - swelling of the nasal mucosa, atrophic rhinitis.
    Overdose:

    Symptoms: decrease in body temperature, bradycardia, increased blood pressure.

    Treatment: symptomatic.

    Interaction:

    Do not use simultaneously with MAO inhibitors or within 14 days after the end of their use.

    Special instructions:

    May have a resorptive effect.

    With prolonged use, the severity of the vasoconstrictor effect gradually decreases (the phenomenon of tachyphylaxis), and in this connection it is recommended to take a break for several days after 5-7 days of use.

    Form release / dosage:

    Nasal drops 0.05% and 0.1%.

    Packaging:

    2 ml each in a dropper with a valve or 10 ml, 15 ml, 20 ml in a tube-Droppers with a screw mouth fromor from polymer materials.

    Tube-dropper with screw neck screw cap screws from polymeric materials. On a tube-dropper stick labels self-adhesive or text labels are applied directly on a tube-dropper methe ink jet print.

    1 tube of a dropper for 2 ml, 10 ml, 15 ml, 20 ml or 2, 5, 10 tubes of 2 ml each with instruction for use placed in a pack of cardboard.

    20 tubes of 10 ml, 15 ml, 20 ml with an equal number of instructions for The change is placed in a pack of cardboard.

    Tube-dropper for 10 ml, 15 ml, 20 ml with instructions for use are box of cardboard (For hospitals).

    Tube-dropper for 10 ml, 15 ml, 20 ml with an equal number of instructionsis placed in a group package.

    Storage conditions:

    In the dark place at a temperature of no higher than 25 ° C.

    Keep out of the reach of children.

    Shelf life:

    3 years. Do not use after expiration date indicated on the package.

    Leave conditions
    Terms of leave from pharmacies:Without recipe
    Registration number:LS-001313
    Date of registration:31.12.2010 / 26.12.2016
    Expiration Date:Unlimited
    The owner of the registration certificate:UPDATE OF PFC, CJSC UPDATE OF PFC, CJSC Russia
    Manufacturer: & nbsp
    Information update date: & nbsp17.06.2018
    Illustrated instructions
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