Naphthyzine - instructions for use, dose, side effects, contraindications

Vasoconstrictor. Excites alpha1 and alpha2-adrenergic receptors, has anti-edematous action. The vasoconstrictive effect is manifested with local application on the nasal mucosa. When rhinitis facilitates nasal breathing, reducing the flow of blood to the venous sinuses.

Pharmacokinetics:

The vasoconstrictive effect comes in a few minutes and lasts for several hours.

Indications:

In acute rhinitis, allergic rhinitis, to facilitate the conduct of a rhinoscopy, to stop nasal bleeding.

Contraindications:

Hypersensitivity, hypertension, severe atherosclerosis, thyrotoxicosis, children under 1 year (for 0.05 % solution), chronic rhinitis, severe eye diseases, diabetes mellitus, tachycardia, simultaneous administration of monoamine oxidase inhibitors and> up to, 14 days after the end of their use, age to 18 years (for 0.1% solution).

Pregnancy and lactation:Not recommended for use in pregnancy. Only during lactation (breastfeeding) the use of the drug is possible, if the benefit to the mother exceeds the potential risk for the child. It is necessary to consult a doctor.

Dosing and Administration:

The drug is administered intranasally.

- In acute and allergic rhinitis, adults are prescribed 1-3 drops of 0.05-1.1% solution 3-4 times a day. Children are assigned 0.05 % aqueous solution (or 0.025 % solution, diluting 0.05 % solution with distilled water): from 1 to 12 years to 6 years - 1-2 drops, from 6 to 15 years - 2 drops 1-3 times a day.

- At a rhinoscope for a prolongation of a superficial anesthesia apply on 2 4 drops of 0,1% of a solution with 1 ml anesthetic.

- With nasal bleeding injected into the nasal cavity tampons, moistened with 0.05% solution of naphthyzine.

Side effects:

From the central nervous system: headache.

From the cardiovascular system: tachycardia, increased blood pressure, reactive hyperemia.

From the digestive system: nausea.

Local reactions: irritation, swelling of the nasal mucosa, when used for more than 1 week - swelling of the nasal mucosa, atrophic rhinitis.

If the side effects indicated in the manual are aggravated, or if you notice any other side effects not listed in the instructions, tell your doctor.

Overdose:

Symptoms: decreased body temperature, bradycardia, increased arterial pressure. Treatment: symptomatic.

Interaction:Do not use simultaneously with monoamine oxidase inhibitors or within 14 days after the end of their use.

Special instructions:

May have a resorptive effect.

With prolonged use, the severity of the vasoconstrictor effect gradually decreases (the phenomenon of tachyphylaxis), in connection with which it is recommended after 5-7 days of use to take a break for several days.

Effect on the ability to drive transp. cf. and fur:During the treatment period, care must be taken when driving vehicles.

Form release / dosage:

Nasal drops 0.05% and 0.1%.

Packaging:

1.3 ml, 1.5 ml, 2 ml or 5 ml in a tube-dropper polymer.

1, 2, 4, 5 or 10 tubes with instructions for the use of the drug and instructions for the use of a tube-dropper in a pack of cardboard with partitions or without partitions.

5 ml or 10 ml into the bottle-dropper polymer. 1 or 2 vials of a dropper with instructions for the use of the drug and instructions for the use of a vial-dropper in a pack of cardboard.

5 ml into glass bottles.

1 a bottle complete with a dropper in a sterile version and instructions for the use of the drug in a pack of cardboard.

5 bottles in a planar cell packaging made of a polyvinyl chloride film. In the outline of the cell pack, complete with 5 droppers in a sterile version and instructions for the use of the drug in a pack of cardboard.

Storage conditions:

In the dark place at a temperature of no higher than 15 ° C (for the drug in a tube-droppers, a bottle of droppers); in the dark place at a temperature of no higher than 25 ° C (for the drug in vials).

Keep out of the reach of children.

Shelf life:

1 year in a tube-droppers and in a vial or flask-droppers.

2 year in vials.

After opening the tube-dropper, the bottle-dropper and bottle - 1 month. Do not use after the expiry date printed on the package.

Terms of leave from pharmacies:Without recipe

Registration number:PL-000807

Date of registration:03.10.2011

The owner of the registration certificate:MOSCOW ENDOCRINE FACTORY, FSUE MOSCOW ENDOCRINE FACTORY, FSUE Russia

Manufacturer: & nbsp

MOSCOW ENDOCRINE FACTORY, FSUE Russia

Information update date: & nbsp30.07.2015

Illustrated instructions

Instructions

Naphthysine (Naphthyzin)