Active substanceNaphazolineNaphazoline
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  • Dosage form: & nbsptoApli nasal
    Composition:Per 1 ml:

    active substance: Naphthyzine - 0.0005 g or 0.001 g;

    Excipients: Boric acid - 0.02 g, purified water - up to 1 ml.

    Description:Pcolored, colorless or slightly colored liquid.
    Pharmacotherapeutic group:Antitussive medication - alpha-adrenomimetic
    ATX: & nbsp

    A.01.A.A.08   Naphazoline

    Pharmacodynamics:Alymph-adrenostimulating agent, provides rapid, pronounced and prolonged vasoconstrictive action against the vessels of the mucous membranes (reduces swelling, flushing, exudation). Relieves nasal breathing in rhinitis. After 5-7 days there is tolerance.
    Indications:

    Acute rhinitis, allergic rhinitis, sinusitis, eustachitis, laryngitis, laryngeal edema of allergic genesis, laryngeal edema on the background of irradiation, hyperemia of the mucosa after operations on the upper respiratory tract.

    To stop nasal bleeding, to facilitate the conduct of a rhinoscopy, to extend the action of local anesthetics used for superficial anesthesia.
    Contraindications:

    - Hypersensitivity to the components of the drug,

    - arterial hypertension,

    - severe atherosclerosis,

    - hyperthyroidism,

    - children's age to 1 year (for 0.05% solution),

    - children's age to 18 years (for 0.1% solution),

    - chronic rhinitis,

    - severe eye diseases,

    - diabetes,

    - tachycardia,

    - simultaneous administration of monoamine oxidase inhibitors (MAO) and a period of up to 14 days after the end of their use.

    Carefully:Pregnancy, the period of breastfeeding.
    Pregnancy and lactation:

    Use during pregnancy and during breastfeeding is possible only if the expected effect for the mother exceeds the potential risk to the fetus or child.

    Dosing and Administration:

    In otorhinolaryngology apply intranasal (in each nasal passage).

    Adults appoint 1-3 drops of 0.05-0.1% solution of the drug 3-4 times a day.

    Children use 0.05% solution of the drug (or 0.025% solution of the drug, diluting 0.05% solution with distilled water): from 1 year to 6 years - 1-2 drops 1-3 times a day; from 6 to 18 years - 2 drops 1-3 times a day.

    For diagnostic purposes: after cleaning the nose in each nasal passage, drip 3-4 drops or insert a tampon,moistened in a 0.05% solution of the drug, and leave for 1-2 minutes; when edema of the vocal cords, administer 1-2 ml of 0.05% solution of the drug in small doses with a laryngeal syringe; when bleeding - insert a tampon moistened with 0.05% solution of the drug.

    In rhinitis, the course of treatment should not exceed 5-7 days.

    As an additional drug for surface anesthesia - 2-4 drops per 1 ml of local anesthetic.

    Side effects:

    Nausea, tachycardia, headache, increased blood pressure, reactive hyperemia, swelling of the nasal mucosa.

    Irritation of the mucous membrane of the nasal cavity, when applied for more than 1 week - swelling of the mucous membrane of the nasal cavity, atrophic rhinitis.

    Overdose:

    Symptoms: decrease in body temperature, bradycardia, increased blood pressure.

    Treatment: symptomatic.

    Interaction:

    Do not use simultaneously with monoamine oxidase inhibitors or within 14 days after the end of their use, due to increased risk of development of severe arterial hypertension.

    Slows the absorption of local anesthetic drugs means (lengthens their action at carrying out of a superficial anesthesia).

    Co-administration of other vasoconstrictive drugs increases the risk of side effects.

    Special instructions:

    May have a resorptive effect.

    With prolonged use, the severity of the vasoconstrictor effect gradually decreases (the phenomenon of tachyphylaxis), and in this connection it is recommended to take a break for several days after 5-7 days of use.

    Effect on the ability to drive transp. cf. and fur:

    The drug does not affect the ability to perform potentially hazardous activities requiring increased concentration of attention and speed of psychomotor reactions (including the management of vehicles and work with moving mechanisms).

    Form release / dosage:Nasal drops, 0.05% and 0.1%.
    Packaging:

    For 10 ml, 15 ml in polymeric bottles-droppers, hermetically sealed with polymer stoppers and droppers cap screwed.

    For one 10-ml dropper, 15 ml along with the instructions for use are placed in a pack.

    Storage conditions:

    In the dark place at a temperature of no higher than 25 ° C.

    Keep out of the reach of children.

    Shelf life:

    3 years.

    The bottle should be used after opening for 30 days.

    Do not use after the expiry date printed on the package.

    Terms of leave from pharmacies:Without recipe
    Registration number:LP-003502
    Date of registration:14.03.2016
    Expiration Date:14.03.2021
    The owner of the registration certificate:YUZHFARM, LLC YUZHFARM, LLC Russia
    Manufacturer: & nbsp
    Representation: & nbspYUZHFARM, LLCYUZHFARM, LLC
    Information update date: & nbsp17.06.2018
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