Naphthyzine - instructions for use, dose, side effects, contraindications

Alpha-adrenostimulating, has a rapid, pronounced and long-lasting vasoconstrictive effect against the vessels of the mucous membranes (reduces swelling, flushing, exudation).

Relieves nasal breathing in rhinitis.

After 5-7 days there is tolerance.

Indications:

Acute rhinitis, allergic rhinitis, sinusitis, eustachitis, laryngitis, laryngeal edema of allergic genesis, laryngeal edema on the background of irradiation, hyperemia of the mucosa after operations on the upper respiratory tract.

To stop nasal bleeding, to facilitate the conduct of a rhinoscopy, to extend the action of local anesthetics used for superficial anesthesia.

Contraindications:

- Hypersensitivity to the components of the drug;

- arterial hypertension;

- severe atherosclerosis;

- hyperthyroidism;

- chronic rhinitis;

- severe eye diseases;

- diabetes;

- tachycardia;

- angle-closure glaucoma;

- atrophic rhinitis;

- simultaneous administration of monoamine oxidase inhibitors (MAO) and up to 14 days after the end of their use;

- Children's age to 1 year (for 0.05% solution);

- children under 18 years (for 0.1% solution).

Carefully:

- Ischemic heart disease (angina pectoris);

- hyperplasia of the prostate;

- pheochromocytoma;

- pregnancy;

- the period of breastfeeding.

Pregnancy and lactation:

Use during pregnancy and during breastfeeding is possible only if the expected effect for the mother exceeds the potential risk to the fetus or child.

Dosing and Administration:

In otorhinolaryngology apply intranasal (in each nasal passage).

Adults appoint 1-3 drops of 0,05-0,1% solution of the drug 3-4 times a day.

Children use 0.05% solution (or 0.025% solution of the drug, diluting 0,05% solution with distilled water): from 1 year to 6 years - 1-2 drops 1-3 times a day; from 6 to 18 years - 2 drops 1-3 times a day.

For diagnostic purposes: after cleaning the nose in each nasal passage, drip 3-4 drops or insert a swab soaked in a 0.05% solution of the drug, and leave for 1-2 minutes;

when edema of the vocal cords, administer 1-2 ml of 0.05% solution of the drug in small doses with a laryngeal syringe; with bleeding - insert a tampon moistened with 0.05% solution of the drug.

In rhinitis, the course of treatment should not exceed 5-7 days.

As an additional drug for surface anesthesia - 2-4 drops per 1 ml of local anesthetic.

Side effects:

Nausea, tachycardia, headache, increased blood pressure, reactive hyperemia, swelling of the nasal mucosa.

Irritation of the mucous membrane of the nasal cavity, when applied for more than 1 week - swelling of the mucosa-nasal cavity, atrophic rhinitis.

Overdose:

Symptoms: decrease in body temperature, bradycardia, increased blood pressure.

Treatment: symptomatic.

Interaction:

Do not use simultaneously with monoamine oxidase inhibitors or within 14 days after the end of their use, due to an increased risk of developing severe hypertension.

Slows the absorption of locally anesthetic medications (prolongs their effect in the conduct of surface anesthesia).

Co-administration of other vasoconstrictive drugs increases the risk of side effects.

Special instructions:

May have a resorptive effect.

With prolonged use, the severity of the vasoconstrictor effect gradually decreases (the phenomenon of tachyphylaxime), and in this connection it is recommended to take a break for several days after 5-7 days of use.

Effect on the ability to drive transp. cf. and fur:

The drug does not affect the ability to perform potentially hazardous activities requiring increased concentration of attention and speed of psychomotor reactions (including vehicle management and work) with moving mechanisms.

Form release / dosage:

Nasal drops, 0.05% and 0.1%.

Packaging:

For 10 ml, 15 ml in polymeric bottles or bottles-droppers, hermetically sealed with polymer stoppers drippers and caps screwed.

On the vial or bottle-dropper stick a self-adhesive label.

One bottle or a dropper of 10 ml each, 15 ml together with the instructions for use are placed in a pack of cardboard.

Storage conditions:

In the dark place at a temperature of no higher than 25 ° C.

Keep out of the reach of children.

Shelf life:

3 years.

The bottle or bottle-dropper after opening should be used within 30 days.

Do not use after the expiry date printed on the package.

Terms of leave from pharmacies:Without recipe

Registration number:LP-003925

Date of registration:25.10.2016

Expiration Date:25.10.2021

The owner of the registration certificate:Farmanova, Open CompanyFarmanova, Open Company Russia

Manufacturer: & nbsp

BIOFARMKOMBINAT, LLC Russia

Representation: & nbspBioFarmKombinat, Open CompanyBioFarmKombinat, Open CompanyRussia

Information update date: & nbsp17.06.2018

Illustrated instructions

Instructions

Naphthysine (Naphthyzin)