Active substanceRetinolRetinol Similar drugsTo uncover Widestim® ointment externally RETYNOIDS FNPP, CJSC Russia Retinol capsules ALTAYVITAMINS, CJSC Russia Retinol pills inwards VEROPHARM SA Russia Retinol acetate solution inwards externally TECHNOLOG, PAO Ukraine Retinol acetate drops inwards externally PHARMACEUTICAL FACTORY of St. Petersburg, JSC Russia Retinol acetate solution inwards externally MARBIOFARM, OJSC Russia Retinol acetate capsules inwards externally MARBIOFARM, OJSC Russia Retinol acetate solution inwards MUROMSKY INSTRUMENT-MAKING PLANT, FSUE Russia Retinol acetate (Vitamin A) capsules inwards LYUMI, LLC Russia Retinol acetate (vitamin A) capsules inwards LYUMI, LLC Russia Retinol acetate (vitamin A) capsules inwards TULA PHARMACEUTICAL FACTORY, LTD. Russia Retinol acetate solution in oil solution inwards PHARMACEUTICAL FACTORY of St. Petersburg, JSC Russia Retinola palmitate pills inwards MARBIOFARM, OJSC Russia Retinola palmitate solution inwards RETYNOIDS FNPP, CJSC Russia Dosage form: & nbspThe tablets are coated. Composition:Granules of retinol acetate (vitamin A) - 0.01135 g (33000 ME),Excipients: sugar, talc, calcium, 1-aqueous stearate, potato starch, aerosil, gelatin, titanium dioxide, polyvinylpyrrolidone or povidone-8000, methylcellulose, tropeolin 0 or yellow water-soluble dye, magnesium basic carbon, beeswax. Description:The tablets are yellow, two layers are visible on the transverse section, the inner one is white with a yellowish tinge. Pharmacotherapeutic group:Vitamin. ATX: & nbspA.11.C.A Vitamin AA.11.C.A.01 Retinol Pharmacodynamics:Vitamin A has a restorative effect, normalizes tissue metabolism; participates in oxidation-reduction processes (due to a large number of unsaturated bonds), in the synthesis of mucopolysaccharides, proteins, lipids, in mineral metabolism, and cholesterol formation processes. Strengthens the production of lipase and trypsin, enhances myelopoiesis, cell division processes. Has a positive effect on the function of lacrimal, sebaceous and sweat glands; increases resistance to diseases of the mucous membranes of the respiratory tract and intestines; increases the body's resistance to infection. It enhances the division of skin epithelial cells, rejuvenates the cellular population, inhibits keratinization processes, enhances the synthesis of glycosaminoglycans, activates the interaction of immunocompetent cells with each other and epidermal cells. Stimulates skin regeneration. Participates in the processes of photoreception (contributes to the adaptation of man to the dark).Local action is due to the presence on the cell surface of the epithelium of specific retinol-binding receptors. Pharmacokinetics: Indications:Hypovitaminosis, avitaminosis A. In complex therapy:- Infectious and inflammatory diseases (measles, dysentery, influenza, tracheitis, bronchitis, etc.)- lesions and skin diseases (frostbite, burns, wounds, erosions, ulcers, cracks, ichthyosis, hyperkeratosis, seborrheic dermatitis, psoriasis, neurodermatitis, some forms of eczema, skin tuberculosis)- eye diseases (retinitis pigmentosa, hemostalopia, xerophthalmia, keratomalacia, eczematous lesions of the eyelids)- gastrointestinal diseases (erosive gastroduodenitis, peptic ulcer of the stomach and duodenum)- cirrhosis of the liverAssign to prevent the formation of concrements in the biliary and urinary tract. Contraindications:Hypersensitivity, hypervitaminosis A, pregnancy (I trimester), cholelithiasis, chronic pancreatitis, acute inflammatory skin diseases. Carefully:Use for nephritis, heart failure II-III st. Dosing and Administration:With the preventive and therapeutic purpose, vitamin A is prescribed inside.The daily requirement for vitamin A is 5000 ME (1.5 mg) for an adult; for pregnant and lactating women - 6600 ME (2 mg); Children from 7 years and older - 5000 ME (1.5 mg).The highest single treatment dose for adults is 50 000 ME, the highest daily intake is 100 000 ME. When using higher doses of vitamin A, the possibility of developing hypervitaminosis A should be considered.When diseases of the eyes are prescribed to adults - 50000 - 100000 ME per day.When skin diseases are prescribed per day for 50000 - 100000 ME adults and 5000 -10000-20000 ME children. Side effects:Prolonged, daily intake of vitamin A (100,000 ME-children, 200,000 ME-adults) can cause intoxication, hypervitaminosis A. Symptoms of hypervitaminosis A in adults include headache, drowsiness, lethargy, facial hyperemia, nausea, vomiting, tenderness in the bones of the lower limbs, violation of gait. Children can be observed: fever, drowsiness, sweating, vomiting, skin rashes. It is possible to increase the pressure of the cerebrospinal fluid (with the development of hydrocephalus in infants and protrusion of the fontanel).Hypervitaminosis A: in adults - drowsiness, lethargy, headache, flushing of the face with subsequent peeling, possibly exacerbation of liver diseases, nausea, vomiting, tenderness in the bones of the lower limbs. Interaction:During prolonged therapy with tetracyclines, vitamin A is not recommended (the risk of developing intracranial hypertension increases).Salicylates and glucocorticostroids reduce the risk of side effects. Special instructions:C use caution in acute and chronic nephritis, cardiac decompensation.Do not take other multivitamin complexes at the same time in order to avoid an overdose. Form release / dosage:Coated tablets; 33 thousand ME. Packaging:By 20, 30, 40, 50 pieces in cans of glass mass or in cans or bottles of polymer. 10 tablets per contour cell pack. Each jar or bottle, or 2, 3, 4 or 5 outline cell packs of 10 tablets together with the instructions for use are placed in a pack of cardboard. Storage conditions:List B. Store in a dry, protected from light cool and inaccessible to children, place. Shelf life:2 years. Do not use the drug with expired shelf life. Terms of leave from pharmacies:Without recipe Registration number:LS-001199 Date of registration:27.01.2006 The owner of the registration certificate:VEROPHARM SA VEROPHARM SA Russia Manufacturer: & nbspVEROPHARM SA Russia Information update date: & nbsp06.08.2015 Illustrated instructions × Illustrated instructions Instructions