Active substanceNitcheamideNitcheamide
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  • Dosage form: & nbspdrops for oral administration
    Composition:

    Active substance - nicotinic acid diethylamide - 250 g, adjuvant - purified water up to 1 liter.

    Description:Transparent or slightly opalescent colorless or slightly yellowish or greenish liquid with a peculiar odor.
    Pharmacotherapeutic group:Analeptic remedy
    ATX: & nbsp

    R.07.A.B   Respiratory stimulants

    R.07.A.B.02   Nitcheamide

    Pharmacodynamics:

    Has an analeptic effect. Stimulates the central nervous system: it has an exciting effect on the vasomotor center of the medulla oblongata (especially when the center is oppressed), which leads to an indirect increase in systemic blood pressure. Excites the respiratory center due to the stimulating effect on the chemoreceptors of the sinocarotid reflexogenic zone, which leads to an increase in the frequency and depth of the respiratory movements. The drug has no direct stimulating effect on the heart and a direct stimulating vasoconstrictor effect.

    Pharmacokinetics:Well absorbed in any route of administration. It is subject to rapid biotransformation in the liver with the formation of inactive metabolites, excreted mainly by the kidneys.
    Indications:

    Collapse, hypotonic conditions, weakening of breathing in infectious diseases and during recovery.

    Contraindications:Hypersensitivity, epilepsy, seizures of tonic-clonic seizures in the anamnesis, hyperthermia in children, pregnancy, lactation.
    Pregnancy and lactation:

    Contraindicated in pregnancy and lactation.

    Dosing and Administration:

    Inside, regardless of food intake.

    Adults. 15-40 drops at the reception 2-3 times a day. The highest single dose for adults is 60 drops, daily - 180 drops.

    Children under 10 years old. 2-3 times a day, the number of drops per 1 reception should be equal to the number of full years of the patient.

    Children from ten years old. 10 drops 2-3 times a day.

    Side effects:Anxiety, anxiety, muscle twitching (starting with the circular muscles of the mouth), tonic-clonic seizures, allergic reactions, itching of the skin, face hyperemia, vomiting, disturbance of the heart rhythm.
    Overdose:Symptoms: tonic-clonic convulsions. Treatment: symptomatic.
    Interaction:

    The convulsive effect of Cordiamin strengthens reserpine; the exciting effect on the respiratory center is eliminated by means for general anesthesia; the effect of the drug is weakened by para-aminosalicylic acid and opiniazide; to reduce the analeptic effect and convulsive effects lead to aminazine and other phenothiazine derivatives.

    Enhances the effects of psychostimulants and antidepressants. Reduces the effects of narcotic analgesics, hypnotics, neuroleptics, tranquilizers, anticonvulsants.
    Effect on the ability to drive transp. cf. and fur:

    Care must be taken when driving vehicles and engaging in other potentially hazardous activities that require increased attention and speed of psychomotor reactions.

    Form release / dosage:

    Drops for oral administration.

    Packaging:

    For 15, 25 ml in the bottles of the type FK-15-16-OC-1, FK-25-16-OC-1, sealed with a stopper-dropper type PKP-1, PKP-2 and with a lid type KPRP-16, and 30 ml in flasks of type FV-30-20-OS, sealed with a stopper-drip polyethylene and a cover of a screwed type KPRP-20, or 5 l in vials of glass-mass of the type FP-5000-28-OS with ground cork. The cork and part of the throat is wrapped with parchment soaked in water, tied around the neck with cotton threads N OO or reinforced with 200 LH. Each label is labeled with label paper or writing paper.

    Each vial-dropper (15, 25 ml) or vial (30 ml) is placed in a pack of cardboard chromium-ersatz with an enclosed instruction for medical use.

    Storage conditions:

    AT protected from light and inaccessible to children.

    Shelf life:3 years. Do not use after the expiration date.
    Terms of leave from pharmacies:On prescription
    Registration number:LS-001261
    Date of registration:15.07.2011
    Expiration Date:Unlimited
    The owner of the registration certificate:TECHNOPARK-CENTER, LLC TECHNOPARK-CENTER, LLC Russia
    Manufacturer: & nbsp
    Information update date: & nbsp23.11.2017
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