Active substanceNitcheamideNitcheamide
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  • Dosage form: & nbspdrops for oral administration
    Composition:

    Active substances:

    Nikethamide (diethylamide of nicotinic acid in terms of 100%) 250 g

    Excipients:

    Water purified to 1 liter

    Description:Transparent or slightly opalescent colorless or slightly yellowish or greenish liquid with a peculiar smell.
    Pharmacotherapeutic group:Analeptic remedy
    ATX: & nbsp

    R.07.A.B   Respiratory stimulants

    R.07.A.B.02   Nitcheamide

    Pharmacodynamics:

    Has an analeptic effect. Stimulates the central nervous system: it has an exciting effect on the vasomotor center of the medulla oblongata (especially when the center is oppressed), which leads to an indirect increase in systemic blood pressure. Excites the respiratory center due to the stimulating effect on the chemoreceptors of the sinocarotid reflexogenic zone, which leads to an increase in the frequency and depth of the respiratory movements. The drug has no direct stimulating effect on the heart and a direct stimulating vasoconstrictor effect.

    Indications:Collapse, hypotonic conditions, weakening of breathing in infectious diseases and during recovery.
    Contraindications:

    Hypersensitivity, epilepsy, seizures of tonic-clonic seizures in the anamnesis and predisposition to convulsions, hyperthermia in children, pregnancy, lactation. Children up to 3 years.

    Dosing and Administration:

    Inside, regardless of food intake.

    Adults: 15-40 drops per reception 2-3 times a day.The highest single dose for adults is 60 drops, daily -180 drops.

    Children from 3 to 10 years old: 2-3 times a day, the number of drops per 1 reception should be equal to the number of full years of the patient.

    Children from 10 years: 10 drops 2-3 times a day.
    Side effects:

    Anxiety, anxiety, muscle twitching (starting with the circular muscles of the mouth), tonic-clonic seizures, allergic reactions, itching of the skin, face hyperemia, vomiting, disturbance of the heart rhythm.

    Overdose:Symptoms: tonic-clonic convulsions. Treatment: symptomatic.
    Interaction:

    The convulsive effect of Cordiamin strengthens reserpine; the exciting effect on the respiratory center is eliminated by means for general anesthesia; the action of the drug weakens para-aminosalicylic acid and opiniazide; to reduce the analeptic effect and convulsive effects lead to aminazine and other phenothiazine derivatives.

    Enhances the effects of psychostimulants and antidepressants. Reduces the effects of narcotic analgesics, hypnotics, neuroleptics, tranquilizers, anticonvulsants.

    Form release / dosage:

    Drops for oral administration 25%.

    Packaging:For 15 and 25 ml in a vial of a dropper, ukuporenny stopper-dropper polyethylene and a lid. To 30 ml in a bottle of orange glass with a screw neck, ukuporenny stopper-dropper polyethylene and a cap screwed. Each vial with the instruction for the use of the drug is placed in a cardboard box.
    Storage conditions:

    List B. At a temperature not higher than 15 ° C, in a place protected from light.

    Keep out of the reach of children.

    Shelf life:

    3 years. Do not use after the expiration date.

    Terms of leave from pharmacies:On prescription
    Registration number:LSR-001030/09
    Date of registration:11.02.2009 / 16.12.2016
    Expiration Date:Unlimited
    The owner of the registration certificate:KAZAN PHARMACEUTICAL FACTORY, CJSC KAZAN PHARMACEUTICAL FACTORY, CJSC Russia
    Manufacturer: & nbsp
    Information update date: & nbsp23.11.2017
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