Active substanceNitcheamideNitcheamide
Similar drugsTo uncover
  • Cordiamine
    drops inwards 
  • Cordiamine
    drops inwards 
  • Cordiamine
    solution for injections 
    ELLARA, LTD.     Russia
  • Cordiamine
    drops inwards 
  • Cordiamine
    drops inwards 
  • Cordiamine
    solution for injections 
  • Cordiamine
    solution for injections 
  • Cordiamine
    solution for injections 
    BIOSINTEZ, PAO     Russia
  • Cordiamine
    solution for injections 
    DALHIMFARM, OJSC     Russia
  • Cordiamine
    solution for injections 
    ESKOM NPK, OAO     Russia
  • Cordiamine
    drops inwards 
  • Cordiamine
    solution for injections 
    ORGANICS, JSC     Russia
  • Cordiamine
    solution for injections 
  • Cordiamin-Darnitsa
    solution for injections 
  • Nitakamid-Eskom
    solution w / m in / in PC 
    ESKOM NPK, OAO     Russia
  • Dosage form: & nbspdrops for oral administration
    Composition:

    Active substance: Nikethamide (nicotinic acid diethylamide) - 250 g; Excipient: purified water up to 1 liter.

    Description:Transparent, colorless or slightly yellowish, or greenish liquid with a characteristic odor.
    Pharmacotherapeutic group:Analeptic remedy
    ATX: & nbsp

    R.07.A.B   Respiratory stimulants

    R.07.A.B.02   Nitcheamide

    Pharmacodynamics:Has an analeptic effect. Stimulates the central nervous system: it has an exciting effect on the vasomotor center of the medulla oblongata (especially when the center is oppressed), which leads to an indirect increase in systemic blood pressure. Excites the respiratory center due to the stimulating effect on the chemoreceptors of the sinocarotid reflexogenic zone, which leads to an increase in the frequency and depth of the respiratory movements. The drug has no direct stimulating effect on the heart and a direct stimulating vasoconstrictor effect.
    Pharmacokinetics:

    Well absorbed in any route of administration. It is subject to rapid biotransformation in the liver with the formation of inactive metabolites excreted mainly by the kidneys.

    Indications:

    Collapse, a condition accompanied by a decrease in blood pressure, a decrease in vascular tone and a weakening of respiration in infectious diseases and during recovery.

    Contraindications:

    Hypersensitivity, epilepsy, seizures in the anamnesis and a predisposition to convulsions, hyperthermia in children, pregnancy, lactation.

    Carefully:

    Children should use the drug only under the supervision of a doctor.

    Pregnancy and lactation:Contraindicated.
    Dosing and Administration:

    Inside, regardless of food intake.

    Adults: 15-40 drops at the reception 2-3 times a day. The highest single dose for adults is 60 drops, daily - 180 drops.

    Children under 10 years old: 2-3 times a day, the number of drops per 1 reception should be equal to the number of full years of the patient.

    Children from 10 years: 10 drops 2-3 times a day.

    To determine the appropriateness of the course use of the drug should consult with a doctor.

    Side effects:

    From the gastrointestinal tract: vomiting.

    From the side of the cardiovascular system: violation of the heart rate.

    From the nervous system: anxiety, anxiety, muscle twitching (starting with the circular muscles of the mouth), tonic-clonic convulsions, hyperemia of the face.

    Allergic reactions: itching of the skin.
    Overdose:

    Symptoms: tonic-clonic convulsions. Treatment: symptomatic.

    Interaction:

    The convulsive effect of cordiodin enhances reserpine; The exciting effect on the respiratory center is eliminated by means for general anesthesia: the action of the drug weakens aminosalicylic acid and opiniazide; to the weakening of the analeptic effect and convulsive chlorpromazine and other phenothiazine derivatives.

    Enhances the effects of psychostimulants and antidepressants. Reduces the effects of narcotic analgesics, hypnotics, neuroleptics, tranquilizers, anticonvulsants.

    Special instructions:

    Effect on the ability to drive transp. cf. and fur:Use with caution when driving and other vehicles.
    Form release / dosage:

    Drops for oral administration, 25%.

    Packaging:On 15 and 25 ml in bottles-droppers of orange glass, ukuporennye a stopper-dropper polyethylene. The bottle together with the instruction for use is placed in a pack of cardboard.
    Storage conditions:

    At a temperature of no higher than 25 ° C, in a place protected from light.

    Keep out of the reach of children.

    Shelf life:

    3 years.

    Do not use after the expiration date printed on the package.

    Terms of leave from pharmacies:Without recipe
    Registration number:LP-002551
    Date of registration:31.07.2014 / 17.08.2016
    Expiration Date:31.07.2019
    The owner of the registration certificate:FACTORY CHEMREACTIVKOMPLEKT, JSC FACTORY CHEMREACTIVKOMPLEKT, JSC Russia
    Manufacturer: & nbsp
    Information update date: & nbsp23.11.2017
    Illustrated instructions
      Instructions
      Up