Oxygen medical gaseous - instructions for use, dose, side effects, contraindications

It is highly effective in hypoxic conditions. Significantly improves oxygen saturation of tissues and hemodynamics, protects the brain from hypoxia. Has a metabolic and anthelmintic effect. In conditions of normobaric hypoxia, it increases the resistance of the organism to endogenous and exogenous pathological factors.

Indications:

- Diseases of the respiratory system (including pneumonia, bronchial asthma), cardiovascular system (including chronic heart failure, collapse, arrhythmias, pulmonary edema);

poisoning with carbon monoxide, hydrocyanic acid, asphyxiating substances (including chlorine, phosgene);

- weakening of breathing in the postoperative period;

- ischemia of the lower extremities, trauma of the limbs;

- cerebrovascular diseases;

- hyperbaric oxygenation (heart and lung operations,reconstructive surgery on the gastrointestinal tract organs (GI) tract, intoxication, anemia, peptic ulcer and 12 duodenal ulcer, chronic hepatitis);

- hypoxic therapy (coronary heart disease, arterial hypertension, gastrointestinal diseases, asthenia, depression, fatigue, condition after radiation therapy).

Contraindications:

Hyperbaric oxygenation: the presence of cavities in the lungs, bronchopleural fistula; unoccupied pneumothorax; violation of patency of the auditory tubes and ducts connecting the sinuses with the external environment; acute respiratory viral infections; epilepsy; arterial hypertension; neoplasms.

Carefully:

Hyperbaric oxygenation: bronchial asthma, congenital spherocytosis, high fever, optic neuritis, upper respiratory tract infection, pregnancy, simultaneous administration of cisplatin, doxorubicin, disulfiram, mafenide (increasing the toxicity of these drugs), emphysema, barotrauma of the ears.

Pregnancy and lactation:

Can be used in pregnancy and breastfeeding,if the potential benefit to the mother exceeds the possible risk to the fetus or child.

Dosing and Administration:

Inhalation, in a concentration of 40-60% in a mixture with air, in an amount of 4-5 l / min.

When breathing is weakened in the postoperative period, when poisoning, intoxication is used 100% oxygen or a mixture of carbonic acid.

Oxygenotherapy.

Dosage regimen in all age groups, except for newborns, coincides. To introduce oxygen in high and low concentrations, different equipment is used. The minimum concentration of oxygen should not be lower than its content in atmospheric air (20.9%).

Systems for inhalation with a fixed concentration of oxygen (regardless of the patient's breathing attempts): high flow - masks that provide oxygen supply at a high flow rate; low flow - anesthesia contours. In these systems, the oxygen concentration is set by the doctor.

Systems for inhalation, providing the supply of different concentrations of oxygen (depending on the patient's inspiration): without recycling - catheters and cannulas; with recirculation - oxygen masks.These systems work only in conditions of self-breathing of the patient who inhales the gas mixture.

The oxygen content of the gas mixture will depend on the condition of the patient and the device used.

In newborns, the concentration of oxygen in the inhaled mixture should not exceed 40% (the risk of retrolental fibroplasia).

In elderly patients with chronic bronchitis, the inhaled oxygen concentration should be increased by 1% and not exceed 30% (most often).

Hyperbaric oxygenation: the procedure is carried out in special pressure chambers, for therapeutic purposes apparatuses (single-chamber chambers) are used that create an oxygen pressure of 1.2-1.6-2 atm. Conduct 1 session per day (40-60 minutes), the course of treatment - 8-10 sessions. With peptic ulcer of stomach and duodenum, chronic hepatitis is injected under a pressure of 0.7-1 excess atm (sessions of 45 minutes); course of treatment - 15 sessions.

Hypoxic therapy: special training that leads to oxygen deficiency (normobaric hypoxia) by using gas mixtures with a reduced oxygen content to create an artificial hypoxia (at normal atmospheric pressure).

Side effects:

Hyperbaric oxygenationhypoglycaemia, headache, numbness of fingers, transient visual impairment, barotrauma of the ears (ear pain, damage and rupture of the tympanic membrane) and paranasal sinuses, fatigue, acceleration of cataract ripening, rarely acute oxygen intoxication (convulsions, pulmonary edema).

Oxygen therapy: myocardial ischemia in patients who underwent myocardial infarction.

Overdose:

With prolonged and unsystematic application of high concentrations of oxygen (over 60-80%) with a large flux (over 6-8 l / minute) there is a danger of hyperoxygenation and as a consequence - pulmonary edema. With the prolonged action of oxygen, decompensation reactions develop, manifested by functional and structural disorders in various systems and organs.

Signs of oxygen intoxication appear after a certain period. Its duration may depend on individual sensitivity to oxygen, temperature and humidity of the environment, concentration in the inspired gas mixture, emotional and physical loads, the state of the central nervous system, etc.

Treatment: symptomatic.

Interaction:

Interaction with other drugs has not been investigated.

Form release / dosage:

The gas is compressed.

Packaging:

6,3 m³ in a balloon equipped with a first-opening control device.

Storage conditions:

In a dry separate room or outdoors under a canopy that protects from precipitation and direct sunlight, away from heating sources and open fire sources, out of the reach of children.

Storage of filled cylinders at an air temperature above 60 ° C is not allowed.

Do not allow oxygen to contact with oils and other organic substances in order to avoid an explosion.

Shelf life:

18 months from the date of filling the cylinder.

Do not use after the expiration date.

Terms of leave from pharmacies:For hospitals

Registration number:LSR-006146/10

Date of registration:30.06.2010

Expiration Date:Unlimited

The owner of the registration certificate:MOSCOW COKE AND GAS FACTORY, OJSC MOSCOW COKE AND GAS FACTORY, OJSC Russia

Manufacturer: & nbsp

MOSCOW COKE AND GAS FACTORY, OJSC Russia

Information update date: & nbsp11.01.2018

Illustrated instructions

Instructions

Oxygen medical gaseous (Medical gaseous oxygen)