Oxygen medical gaseous - instructions for use, dose, side effects, contraindications

Antihypoxic agent, increases oxygenation of tissues, improves hemodynamics and protects the head brain from hypoxia aboutIt shows the metabolic action.

In conditions of normobaric hypoxia, it increases the resistance of the organism to endogenous and exogenous pathological factors.

Indications:

- Hypoxia in diseases of the respiratory system (including pneumonia, bronchial asthma);

- poisoning with carbon monoxide, hydrocyanic acid, asphyxiating substances (including chlorine, phosgene);

- weakening of breathing in the postoperative period;

- ischemia of the lower extremities, trauma of the limbs;

- cerebrovascular diseases;

- Hyperbaric oxygenation (heart and lung operations, reconstructive surgery on the organs of the gastrointestinal fact, intoxication, anemia, peptic ulcer and duodenal ulcer, chronic hepatitis);

- Hypoxic therapy (coronary heart disease, arterial hypertension, gastrointestinal disorders, asthenia, depression, fatigue, condition after radiation therapy).

Contraindications:

Hyperbaric oxygenation: the presence of cavities in the lungs, bronchopleural fistula, unoccupied pneumothorax; violation of patency of the auditory tubes and ducts connecting the sinuses with the external environment; acute respiratory viral infection (ARVI); epilepsy; arterial hypertension; neoplasms.

Carefully:

Hyperbaric oxygenation: bronchial asthma, congenital spherocytosis, high fever, optic neuritis, upper respiratory tract infection, simultaneous administration of cisplatin, doxorubicin, disulfiram, mafenide (increased toxicity of these drugs), emphysema, barotrauma of the ears.

Pregnancy and lactation:

Due to the lack of special clinical studies during pregnancy and breastfeeding, the drug should be used when the benefit to the mother exceeds the potential risk to the fetus and / or the baby and under the direct supervision of the doctor.

Dosing and Administration:

1. Inhalation:

- andnalyatsionno, in a concentration of 40-60%, in a mixture with air, in an amount of 4-5 l / min;

- PIn the weakening of respiration in the postoperative period, in etching, intoxication, 100% oxygen or a mixture of carbonic acid.

Dosage regimen in all age groups, except for newborns, coincides. To conduct oxygen in high and low concentrations, different equipment is used. The minimum concentration of oxygen should not be lower than its content in atmospheric air (20.9%).

inhalation system with a fixed oxygen concentration (regardless of patient breathing attempts): vysokopotochnyh - mask, providing an oxygen supply with a high flow rate; low flow - anesthesia contours. In these systems, the concentration is set by the doctor.

Systems for inhalation, providing the supply of different concentrations of oxygen (depending on the patient's inspiration): without recycling - catheters and cannulas; with recirculation - oxygen masks. These systems work only in conditions of self-breathing of the patient who inhales the gas mixture. The oxygen content of the gas mixture will depend on the condition of the patient and the device used.

In newborns, the concentration of oxygen in the inhaled mixture should not exceed 40% (the risk of retrolental fibroplasia).

In elderly patients with chronic bronchitis, the inhaled oxygen concentration should be increased by 1% and not exceed 30% (most often).

2. Hyperbaric oxygenation.

The procedure is carried out in special pressure chambers:

- for therapeutic purposes, use apparatus (single chamber), creating an oxygen pressure of 1.2-1.6-2 atm. Conduct 1 session per day (40-60 minutes), the course of treatment - 8-10 sessions.

- with peptic ulcer of stomach and duodenum, chronic hepatitis is injected under a pressure of 0.7-1 excess atm. (sessions but 45 minutes), treatment course - 15 sessions.

3. Hypoxic therapy:

- PThe development of special training, leading to oxygen deficiency (normobaric hypoxia) by using gas mixtures with a reduced oxygen content to create artificial hypoxia (at normal atmospheric pressure).

Side effects:

Hyperbaric oxygenation: hypoglycemia, headache, numbness of fingers, transient visual impairment, barotrauma of the ears (ear pain, damage and rupture of the tympanic membrane) and paranasal sinuses, fatigue,acceleration of cataract ripening, rarely - acute oxygen intoxication (convulsions, pulmonary edema).

Oxygen therapy: myocardial ischemia in patients who underwent myocardial infarction.

Overdose:

With prolonged and unsystematic application of high concentrations of oxygen (over 60-80%) with a large flux (over 6-8 l / min) there is a danger of hyperoxygenation and as a consequence - pulmonary edema. With prolonged action of oxygen, decompensatory reactions develop, manifested by functional and structural disorders in various systems and organs.

Signs of oxygen intoxication appear after a certain period. Its duration may depend on individual sensitivity to oxygen, temperature and humidity of the environment, concentration in the inspired gas mixture, emotional and physical loads, the state of the central nervous system, etc.

Treatment: symptomatic.

Interaction:Not studied.

Form release / dosage:

The gas is compressed.

Packaging:

0.31 m³ (for cylinders with a capacity of 2 dm³).

1.56 m³ (for cylinders with a capacity of 10 dm³).

6,24 m³ (for cylinders with a capacity of 40 dm³).

The volume of the contents of the package is given for conditions: excess pressure (14.7 ± 0.5) MPa

[(150 ± 5 kgf / cm²)], the temperature is 20 ° C. Cylinders are equipped with a valve in accordance with GOST 26460-85 and a first-opening control device complete with instructions for medical use.

They use steel seamless blue cylinders with a black inscription "Oxygen medical" on the circumference.

The label is applied / attached to the container.

Storage conditions:In a dry separate room or in open areas under a canopy that protects from atmospheric precipitation and direct sunlight, away from heating sources and open fire sources at temperatures from minus 50 ° C to 50 ° C.

Keep out of the reach of children.

Shelf life:

18 months from the date of manufacture.

Do not use after the expiration date.

Terms of leave from pharmacies:For hospitals

Registration number:LP-003003

Date of registration:25.05.2015

Expiration Date:25.05.2020

The owner of the registration certificate:State Budgetary Institution of the Republic of Komi Main Directorate of Material and Technical Provision of Public Health of the Republic of KomiState Budgetary Institution of the Republic of Komi Main Directorate of Material and Technical Provision of Public Health of the Republic of Komi Russia

Manufacturer: & nbsp

State Budgetary Institution of the Republic of Komi "General Directorate of Material and Technical Provision of Public Health of the Republic of Komi" Russia

Information update date: & nbsp11.01.2018

Illustrated instructions

Instructions

Oxygen medical gaseous (Medical gaseous oxygen)