Active substanceOxygenOxygen
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  • Dosage form: & nbspcompressed gas
    Composition:

    Oxygen medical gaseous - 100%.

    Description:

    Colorless gas without a smell.

    Pharmacotherapeutic group:Antihypoxic agent
    ATX: & nbsp

    V.03.A.N   Medical gases

    Pharmacodynamics:

    It is highly effective in hypoxic conditions. Significantly improves oxygen saturation of tissues and hemodynamics, protects the brain from hypoxia. Has a metabolic and anthelmintic effect.

    In conditions of normobaric hypoxia, it increases the resistance of the organism to endogenous and exogenous pathological factors.

    Indications:

    Hypoxia: with respiratory diseases (including pneumonia, bronchial asthma), diseases of the cardiovascular system (including chronic heart failure, collapse, arrhythmias, pulmonary edema); poisoning with carbon monoxide, hydrocyanic acid, asphyxiating substances (including chlorine, phosgene); weakening of breathing in the postoperative period; ischemia of lower extremities,injuries of limbs; cerebrovascular diseases of the brain; hyperbaric oxygenation (heart and lung operations, reconstructive surgery on the organs of the gastrointestinal tract, intoxication, anemia, peptic ulcer and duodenal ulcer, chronic hepatitis); Hypoxytherapy (coronary heart disease, arterial hypertension, gastrointestinal tract diseases, asthenia, depression, fatigue, condition after radiation therapy).

    Carefully:

    Hyperbaric oxygenation: the presence of cavities in the lungs, pneumothorax, bronchopleural fistula; violation of patency of the auditory tubes and ducts connecting the sinuses with the external environment; acute respiratory viral infections; epileptiform seizures in the anamnesis; neoplasms; arterial hypertension.

    Pregnancy and lactation:Can be used in pregnancy and breastfeeding, if the potential benefit to the mother exceeds the possible risk to the fetus or child.
    Dosing and Administration:

    Inhalation, in a concentration of 40-60% in a mixture with air, in an amount of 4-5 l / min. When breathing is weakened in the postoperative period, when poisoning, intoxication is used 100% oxygen or a mixture with carbon dioxide.

    Inhalation is carried out through masks or tubes, attached by means of special devices to a cylinder with oxygen, or using rubber cushions.

    Hyperbaric oxygenation: the procedure is carried out in special pressure chambers; for therapeutic purposes, apparatuses (single-chamber) are used that create an excess oxygen pressure of 1.2-1.6-2.0 atm. Conduct 1 session per day (40-60 min); course of treatment 8-10 sessions. With gastric ulcer and duodenal ulcer, chronic hepatitis is injected under a pressure of 0.7-1 excess atm. (sessions for 45 minutes); course of treatment - 15 sessions.

    Hypoxicotherapy: special training, leading to oxygen deficiency (normobaric hypoxia), by using gas mixtures with a reduced oxygen content to create artificial hypoxia (at normal atmospheric pressure).

    Side effects:

    Hyperbaric oxygenation: hypoglycemia, headache, numbness of fingers, transient visual impairment, barotrauma of the ears (ear pain, damage and rupture of the eardrum) and paranasal sinuses, fatigue, acceleration of cataract ripening; rarely - acute oxygen intoxication (convulsions, pulmonary edema).

    Oxygen therapy: myocardial ischemia in patients who underwent myocardial infarction.

    Overdose:

    With prolonged and unsystematic application of high concentrations of oxygen (over 60-80%) with a large flux (over 6-8 l / minute) there is a danger of hyperoxygenation and as a consequence - pulmonary edema. With prolonged action of oxygen, decompensatory reactions develop, manifested by functional and structural disorders in various systems and organs.

    Signs of oxygen intoxication appear after a certain period. Its duration may depend on individual sensitivity to oxygen, temperature and humidity of the environment, concentration in the inspired gas mixture, emotional and physical loads, the state of the central nervous system, etc.

    Treatment: symptomatic.

    Interaction:

    Not investigated.

    Form release / dosage:

    The gas is compressed.

    Packaging:

    By 6300 dm3 in a balloon equipped with a first-opening control device.

    Storage conditions:

    In a dry separate room or outdoors under a canopy that protects from precipitation and direct sunlight, away from heating sources and open fire sources, out of the reach of children.

    Storage of filled cylinders at an air temperature above 60 ° C is not allowed.

    Do not allow oxygen to contact with oils and other organic substances in order to avoid an explosion.

    Shelf life:

    18 months from the date of filling the cylinder.

    Do not use after the expiration date.

    Terms of leave from pharmacies:For hospitals
    Registration number:LP-000351
    Date of registration:22.02.2011
    Expiration Date:22.02.2016
    Date of cancellation:2014-05-12
    The owner of the registration certificate:Mineral Fertilizers, OJSCMineral Fertilizers, OJSC Russia
    Manufacturer: & nbsp
    Information update date: & nbsp11.01.2018
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