St. John's wort - instructions for use, doses, side effects, contraindications

They are applied externally as an astringent and anti-inflammatory agent for lubricating the gums and rinsing the mouth in the prevention and treatment of gingivitis and stomatitis.Inside St. John's wort infusion is used as an astringent for chronic colitis (as part of complex therapy).

Contraindications:

Hypersensitivity to the components of the drug, pregnancy, lactation, children under 12 years.

Carefully:

With caution: liver disease, alcoholism, craniocerebral injury, brain disease.

Dosing and Administration:

Inside - 40-50 drops per reception 3-4 times a day; place for lubricating the gums and rinses - 30-40 drops per ½ cup of water. The course of treatment is 5-10 days.

Side effects:

Allergic reactions: skin itching, skin rash, eczema, skin pigmentation, photosensitivity (more often in HIV-infected patients), increases sensitization to animal wool.

From the side of the central nervous system: anxiety, excessive fatigue, headache.

From the digestive system: nausea, epigastric pain, dry mouth, abdominal pain, flatulence, diarrhea or constipation, anorexia.

Interaction:

As an activator of microsomal oxidation, it can inhibit the therapeutic activity of drugs that undergo metabolism in the liver.

Increases the antidepressant effect of monoamine oxidase inhibitors, but increases the risk of developing hypertensive crises.

When combined with fluoxetine, paroxetine, sertraline, fluvoxamine, or citalopram, it increases the hemolytic reactions and the course of the "serotonin syndrome" (dizziness, nausea, vomiting, headache, epigastric pain, anxiety, confusion, confusion, anxiety and irritability).

The drug is able to enhance the photosensitizing effect of other drugs, in particular tetracyclines, sulfonamides, thiazide diuretics, quinolones, piroxicam.

Reduces the hypotensive effect of reserpine.

Reduces the concentration of cyclosporine in the blood.

St. John's wort reduces the concentration in the blood and the effectiveness of indinavir therapy.

With simultaneous use with ethinyl estradiol and desogestrel, the risk of bleeding increases.

Increases the metabolic rate of theophylline.

Reduces the concentration in the blood of digoxin, reduces its toxicity.

Special instructions:

During treatment should avoid UV radiation (including solarium, UV lamps, prolonged exposure to sunlight).

The absolute alcohol content in the maximum single dose of the drug for adults is 0.36 g; the maximum daily dose of the drug for adults is 1.3 g.

Effect on the ability to drive transp. cf. and fur:

During the treatment period, care must be taken when driving vehicles and engaging in other potentially hazardous activities that require increased concentration and speed of psychomotor reactions.

Form release / dosage:

Tincture. To 25 ml in bottles of orange glass.

Packaging:

To 25 ml in bottles of orange glass. Each bottle, together with the instructions for use, is placed in a pack of cardboard.

Storage conditions:

In the dark place at a temperature of no higher than 20 ° C.

Keep out of the reach of children.

Shelf life:

Shelf life 4 years.

Do not use after the expiry date printed on the package.

Terms of leave from pharmacies:Without recipe

Registration number:P N001828 / 01

Date of registration:25.11.2010

The owner of the registration certificate:MUROMSKY INSTRUMENT-MAKING PLANT, OJSC MUROMSKY INSTRUMENT-MAKING PLANT, OJSC Russia

Manufacturer: & nbsp

MUROMSKY INSTRUMENT-MAKING PLANT, OJSC Russia

Information update date: & nbsp20.11.2012

Illustrated instructions

Instructions

St. John's Wort (Hyperici tinctura)