Levomycetin - instructions for use, dose, side effects, contraindications

The active substance of the drug is chloramphenicol - broad spectrum antibiotic. Chloramphenicol - bacteriostatic antibiotic, disrupts the process of protein synthesis in a microbial cell (having good lipophilicity, penetrates through the bacterial cell membrane and back binds to the subunit 5OS bacterial ribosomes, in which the movement of amino acids to growing peptide chains is delayed, which leads to a violation of protein synthesis). It is active against most strains of gram-positive and gram-negative microorganisms resistant to penicillin, tetracyclines, sulfonamides.

Indications:Furuncles, pustular skin diseases.

Contraindications:

Individual intolerance, pregnancy and lactation, oppression of bone marrow hematopoiesis, acute intermittent porphyria, deficiency of glucose-6-phosphate dehydrogenase, severe renal and hepatic disorders, skin diseases (fungal diseases, psoriasis, eczema), neonatal period (up to 4 weeks ).

Carefully:

Early childhood.

Dosing and Administration:

External, damaged areas are treated with a cotton swab dipped in a solution, several times a day.

Side effects:

Allergic reactions: skin rash, angioedema.

On the part of the organs of hematopoiesis: rarely - thrombocytopenia, erythropenia, aplastic anemia.

Interaction:

With simultaneous use with erythromycin, clindamycin, lincomycin, there is a mutual weakening of the effect due to the fact that chloramphenicol can displace these drugs from the bound state or interfere with their binding to the subunit 50S bacterial ribosomes.

Special instructions:

Children of the first 4 weeks of life are prescribed only in cases of acute necessity.

When applied to large surfaces with the simultaneous use of ethanol, disulfiram-likereactions (flushing of the skin, tachycardia, nausea, vomiting, reflex cough, convulsions).

Form release / dosage:Solution for external use alcohol 0.25%.

Packaging:

By 25 ml or 40 ml in bottles of orange glass type FV, sealed with plastic caps and plastic caps made of polymer materials.

To 25 ml in bottles of droppers of orange glass of type FK complete with a stopper-dropper and a lid polyethylene or ukuporennye stoppers-droppers and caps screwed on plastic.

Vials with the appropriate number of instructions for medical use are placed in a group container.

Storage conditions:

The drug belongs to the list B.

Store in a dark place at a temperature of 12 to 15 ° C.

Keep out of the reach of children.

Shelf life:

2 years. Do not use the product after the expiry date printed on the package.

Terms of leave from pharmacies:Without recipe

Registration number:LSR-004512/10

Date of registration:21.05.2010

Expiration Date:Unlimited

The owner of the registration certificate:KIROVSKAYA PHARMACEUTICAL FACTORY, OJSC KIROVSKAYA PHARMACEUTICAL FACTORY, OJSC Russia

Manufacturer: & nbsp

KIROVSKAYA PHARMACEUTICAL FACTORY, OJSC Russia

Information update date: & nbsp07.03.2018

Illustrated instructions

Instructions

Levomycetin (Levomycetin)