Nosoline - instructions for use, dose, side effects, contraindications

Active ingredient: xylometazolin hydrochloride 1.0 mg. Excipients: sodium hydrophosphate dodecahydrate 3.6 mg, potassium dihydrogen phosphate 9.9 mg, disodium edetate 0.4 mg, sorbitol 30 mg, benzalkonium chloride 0.1 mg, hypromellose 5.0 mg, macrogol 4000 100 mg, water purified to 1 ml .

Description:

transparent colorless or slightly yellowish liquid.

Pharmacotherapeutic group:anticonvulsant - alpha-adrenomimetic.

ATX: & nbsp

R.01.A.A.07 Xylometazoline

Pharmacodynamics:

Xylometazoline is a local vasoconstrictor (decongestant) with an alpha2-adrenomimetic effect, which manifests itself:

- narrowing of the blood vessels of the nasal mucosa;

- reduces blood flow in venous sinuses, thus eliminating the edema and hyperemia of the nasal mucosa and nasopharynx;

- reduces the amount of secreted secret and restores patency of the nasal passages;

- facilitates nasal breathing in rhinitis;

The action comes in a few minutes and lasts for several hours.

Pharmacokinetics:

With topical application, the drug is practically not absorbed, so the plasma concentrations are so small that they can not be determined by modern analytical methods.

Indications:

- acute allergic rhinitis;

- Pollinosis;

- sinusitis;

- otitis media (to reduce edema of the nasopharynx mucosa);

- to prepare the patient for diagnostic manipulation in the nasal passages;

- acute respiratory diseases with phenomena of rhinitis (common cold);

Contraindications:

Hypersensitivity, arterial hypertension, tachycardia, severe atherosclerosis, glaucoma, atrophic rhinitis, surgical interventions on the meninges (in the anamnesis), children's age - up to 6 years.

Carefully:

Lactation period, pregnancy, IHD (angina pectoris), prostatic hyperplasia, hyperthyroidism, diabetes mellitus.

Pregnancy and lactation:During pregnancy and lactation, the drug should be used only as directed by the doctor in charge, if the expected benefit to the mother exceeds the potential risk to the fetus and the baby.

Dosing and Administration:

Intranasally.

For adults and children over 6 years - 2-3 drops in each nasal passage of 0.1% solution, usually enough 4 times a day.

Side effects:

With frequent and / or prolonged use - irritation and / or dryness of the mucous membrane of the nasopharynx, burning, paresthesia, sneezing, hypersecretion. Rarely - edema of the mucous membrane of the nasal cavity, palpitations, tachycardia, arrhythmias, increased blood pressure, headache, nausea, vomiting, insomnia, impaired vision; depression (with prolonged use in high doses).

Overdose:

Symptoms: decreased body temperature, bradycardia, increased blood pressure.

Treatment: symptomatic under the supervision of a physician.

Interaction:

It is possible to enhance the systemic action when used simultaneously with MAO inhibitors and tricyclic antidepressants.

Special instructions:

Before application, it is necessary to clean the nasal passages.

Do not exceed recommended doses and apply for more than 7 days.

Effect on the ability to drive transp. cf. and fur:not described

Form release / dosage:

Nasal drops 0.1% to 10 ml in plastic bottles with a dispenser-dropper.

One bottle together with instructions for medical use is packed in a pack of cardboard.

Packaging:plastic bottles with dispenser-dropper (1) -tacks, cardboard

Storage conditions:

At a temperature of no higher than 25 ° C in a dark place. Keep out of the reach of children.

Shelf life:3 years. Do not use after the expiry date printed on the package.

Terms of leave from pharmacies:Without recipe

Registration number:LP-000456

Date of registration:01.03.2011 / 14.08.2013

Date of cancellation:2016-08-23

The owner of the registration certificate:FIRN M, ZAO FIRN M, ZAO Russia

Manufacturer: & nbsp

FIRN M, ZAO Republic of Belarus

Information update date: & nbsp24.08.2016

Illustrated instructions

Instructions

Nosoline® (Nosolin®)