With frequent and / or prolonged use - irritation and / or dryness of the mucous membrane of the nasopharynx, burning, paresthesia, sneezing, hypersecretion; rarely - swelling of the nasal mucosa, palpitations, tachycardia,arrhythmia, increased blood pressure, vomiting, headache, insomnia, visual impairment, depression (with prolonged use of high doses).