Xylometazoline - instructions for use, dose, side effects, contraindications

Xylometazoline belongs to the group local vasoconstrictor (decongestants) with alpha-adrenomimetic action, causes constriction of the blood vessels of the mucosa of the nasal cavity, eliminating the edema and hyperemia. Relieves nasal breathing with rhinitis. The effect of the drug is a few minutes after his application and continues for 12 hours.

Marine water, which is part of the preparation as an auxiliary component, helps maintain the normal physiological state of the mucous membrane of the nasal cavity, which allows Reduce the symptoms of irritation and dryness that occur with prolonged use of xylometazoline.

Pharmacokinetics:

With topical application xylometazoline practically not absorbed, plasma concentrations are so small that they can not be determined by modern analytical methods.

Indications:

- Acute respiratory diseases (ARI) with phenomena of rhinitis (common cold);

- Acute allergic rhinitis;

- Sinusitis;

- Pollinosis;

- Average otitis media (to reduce edema of the nasopharynx mucosa);

- Preparation of the patient for diagnostic manipulation in the nasal passages.

Contraindications:

Hypersensitivity, arterial hypertension, tachycardia, severe atherosclerosis, glaucoma, atrophic rhinitis, thyrotoxicosis, surgical interventions on the meninges (in the anamnesis), children's age (up to 6 years - for 0.1% solution).

Do not use with monoamine oxidase inhibitors and tricyclic antidepressants.

Carefully:

Pregnancy, lactation, ischemic heart disease (angina pectoris), hyperplasia of the prostate, diabetes; children under 2 years old (for 0.05% solution).

Pregnancy and lactation:If you need to use the drug during pregnancy and lactation, you should consult your doctor to assess the relationship between the benefits to the mother and the potential risk to the fetus / infant.

Dosing and Administration:

Intranasally.

Drops of 0.05%: Infant and age to 6 years - 1-2 drops per each nasal passage 1-2 times a day (no more than 3 times per day), children older than 6 years - 2-3 drops per day each nasal passage 3-4 times a day.

Drops 0.1%: adults and children over 6 years - 2-3 drops in each nasal passage up to 4 times a day.

Side effects:

With frequent and / or prolonged use - irritation and / or dryness of the nasopharyngeal mucosa, burning, tingling, sneezing, hypersecretion.

Rarely - edema of the mucous membrane of the nasal cavity, palpitations, tachycardia, arrhythmias, increased blood pressure, headache, vomiting, insomnia, impaired vision; depression (with prolonged use of high doses).

Overdose:

Symptoms: increased side effects.

Treatment: symptomatic.

Interaction:

Incompatible with monoamine oxidase (MAO) inhibitors and tricyclic antidepressants.

Special instructions:

Before use it is necessary to clean nasal passages.

Do not exceed recommended dose, especially in children and the elderly.

Do not use more than 7 days if the doctor did not recommend a different duration treatment. If after this time symptoms persist, you need to see a doctor.

Effect on the ability to drive transp. cf. and fur:The drug in recommended doses does not affect the rate of reactions when driving vehicles or working with other mechanisms.

Form release / dosage:

Nasal drops 0.05 % and 0,1 %.

Packaging:

Nasal drops 0.05%

For 1 ml, 2 ml in a tube-dropper polymer with a valve. On the tube-dropper stick labels.

1, 5, 10 tubes with the instruction for use are placed in a pack of cardboard.

For 10 ml, 15 ml in bottles of dark glass with a screw mouth, sealed with lids with pipettes.

Labels are applied to vials. Each vial with instructions for use is placed in a pack of cardboard.

Nasal drops 0,1%

2 ml each in a polymer dropper with a valve. On the tube-dropper stick labels. 5 tubes-droppers with instructions for use are placed in a pack of cardboard.

Storage conditions:

In a dry, protected from light place at a temperature of no higher than 25 ° C.

Keep out of the reach of children.

Shelf life:

3 years.

Do not use after the expiry date is validspecified on the package.

Terms of leave from pharmacies:Without recipe

Registration number:LSR-003901/07

Date of registration:19.11.2007 / 18.07.2014

Expiration Date:Unlimited

The owner of the registration certificate:UPDATE OF PFC, CJSC UPDATE OF PFC, CJSC Russia

Manufacturer: & nbsp

UPDATE, PFC CJSC Russia

Information update date: & nbsp05.02.2018

Illustrated instructions

Instructions

Xylometazoline (Xylometazoline)