Active substanceXylometazolineXylometazoline
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  • Dosage form: & nbspnasal drops
    Composition:

    1 ml of the solution contains:

    Xylometazoline hydrochloride 5.0 mg or 10.0 mg.

    Excipients: sodium dihydrogen phosphate, sodium hydrogen phosphate, sodium chloride, benzalkonium chloride, purified water.

    Description:

    Transparent colorless liquid.

    Pharmacotherapeutic group:Antitussive medication - alpha-adrenomimetic
    ATX: & nbsp

    R.01.A.A.07   Xylometazoline

    Pharmacodynamics:

    The alpha-adrenostimulant narrows the blood vessels of the mucous membrane of the nasal cavity, eliminating the edema and hyperemia of the mucosa.

    Relieves nasal breathing in rhinitis.

    The action comes in a few minutes and lasts for several hours.

    Pharmacokinetics:

    With topical application is practically not absorbed, plasma concentrations are so small that they can not be determined by modern analytical methods.

    Indications:

    Acute allergic rhinitis, acute respiratory disease with phenomena of rhinitis, sinusitis, hay fever; otitis media (to reduce edema of the nasopharynx mucosa). Preparation of the patient for diagnostic manipulation in the nasal passages.

    Contraindications:

    Hypersensitivity, arterial hypertension, tachycardia, severe atherosclerosis, glaucoma, atrophic rhinitis, thyrotoxicosis, surgical interventions on the meninges (in the anamnesis), pregnancy, children's age (up to 6 years).

    Carefully:

    Lactation period, IHD (angina pectoris), prostatic hyperplasia, diabetes mellitus.

    Pregnancy and lactation:
    Dosing and Administration:

    Intranasally. Adults and children over 6 years: 2-3 drops in each nasal passage 2 - 3 times a day.

    Do not use more than 3 times a day.

    Side effects:

    When used, it can cause burning in the nose and throat, local irritation, paresthesia, sneezing, hypersecretion, dryness of the nasal mucosa. Allergic reactions are possible.

    Rarely - edema of the nasal mucosa, palpitations, tachycardia, arrhythmias, increased blood pressure, headache, nausea, vomiting, insomnia, impaired vision; depression (with prolonged use in high doses).

    If symptoms occur, discontinue use and consult a doctor.
    Overdose:
    In case of accidental poisoning with xylometazoline while taking it inside, there may be mydriasis, nausea, vomiting, cyanosis, fever, spasms, tachycardia, cardiac arrhythmia, collapse, cardiac arrest, hypertension, pulmonary edema, respiratory disorders, mental disorders, suppression of CNS function, accompanied by drowsiness, body temperature, bradycardia, hypotension, apnea, coma.

    Treatment: gastric lavage, the appointment of activated charcoal, if necessary IVL. To reduce blood pressure, fentolamine I / O slowly in a dose of 5 mg or inside at a dose of 100 mg.

    Vasopressor agents are contraindicated.If necessary, antipyretic and anticonvulsant drugs are used.

    Interaction:

    Do not use simultaneously with MAO inhibitors and tricyclic antidepressants.

    Special instructions:

    It is not recommended frequent and long-term use in chronic diseases of the nasopharynx. In case of "cold" diseases, in cases where crusts are formed in the nose, it is preferable to prescribe in the form of a gel.

    Effect on the ability to drive transp. cf. and fur:
    Form release / dosage:

    Nasal drops 0.05%, 0.1%.

    Packaging:For 10, 15 or 20 ml of the drug in a plastic bottle-dropper with a screw cap made of plastic. On 1 bottle together with the instruction on medical application place in a cardboard pack.
    Storage conditions:

    At a temperature of 15 to 25 ° C.

    Keep out of the reach of children!

    Shelf life:

    3 years.

    Do not use after the expiration date printed on the package.

    Terms of leave from pharmacies:Without recipe
    Registration number:LSR-009541/09
    Date of registration:25.11.2009 / 19.12.2016
    Expiration Date:Unlimited
    The owner of the registration certificate:Danson Trading Pharmaceutical Company LimitedDanson Trading Pharmaceutical Company Limited Vietnam
    Manufacturer: & nbsp
    Representation: & nbspDominanta-Service CJSCDominanta-Service CJSC
    Information update date: & nbsp11.10.2017
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