Active substanceHuman albuminHuman albumin
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  • Dosage form: & nbspsolution for infusions
    Composition:

    Active substance:

    albumin 5% - 50 g; 20% - 200 g;

    Excipients:

    sodium caprylate - 1.5 g; - 6 g;

    sodium chloride 9 g; - 4 g;

    water for injection - up to 1 liter - up to 1 liter

    Description:Transparent liquid is yellow, a greenish shade is allowed.
    Pharmacotherapeutic group:Plasmasuberant
    ATX: & nbsp

    B.05.A.A.01   Albumen

    Pharmacodynamics:

    Plasma-reducing agent obtained by fractionating human plasma. It replenishes the deficiency of plasma albumin, supports the colloid-osmotic (oncotic) blood pressure, rapidly increases blood pressure and circulating blood volume, increases the transition and promotes retention of tissue fluid in the bloodstream, increases the protein supply reserves of tissues and organs. It has detoxification properties.

    Indications:

    Shock (traumatic, operational and toxic); burns accompanied by dehydration and "thickening" of blood; hypoproteinemia, hypoalbuminemia, developing with alimentary dystrophy, nephrotic syndrome, glomerulonephritis, cirrhosis, long-term, purulent processes, lesions of the gastrointestinal tract with impaired absorption or patency.

    Contraindications:

    Hypersensitivity, severe anemia, chronic heart failure II-III stage, hypervolemia, pulmonary edema.

    Carefully:Arterial hypertension, renal failure, thrombosis, continuing internal bleeding, chronic heart failure of stage 1.
    Pregnancy and lactation:

    In pregnancy, the use of human albumin is possible only in cases of extreme necessity. Data on the safety of human albumin use during lactation are absent.

    Dosing and Administration:

    Intravenous drip or stream. A single dose of the drug depends on the concentration of the albumin solution, the initial condition and the age of the patient. A solution of albumin 5% injected at a dose of 200-300 ml, if necessary, the dose of 5% solution can be increased to 500-800 ml.

    An albumin solution of 5% should be administered at a rate of no more than 50-60 cap / min. A single dose of 20% albumin is 100 ml. The injection rate is not higher than 40 cap / min. For the treatment of cerebral edema, hyperoncotic solutions of albumin (10-20%).

    The jet injection of albumin solutions is acceptable for shocks of different genesis for rapid increase in blood pressure.

    In pediatric practice, taking into account the concentration of albumin solutions, their dosages should be calculated in ml / kg (not more than 3 ml / kg).

    In elderly patients, avoid the use of concentrated albumin solution (20%) and rapid administration of a 5% solution of albumin, since this can lead to an overload of the cardiovascular system.

    Side effects:Allergic reactions, hives, hyperthermia, pain in the lumbar region.
    Overdose:No data.
    Interaction:Data on the interaction of albumin with other drugs are absent.
    Special instructions:

    The albumin solution should be clear and free of slurry and sediment.

    Patients with dehydration before administration of albumin should Ensure a sufficient supply of fluid in the body.

    Effect on the ability to drive transp. cf. and fur:

    The drug does not affect the ability to drive vehicles, mechanisms.

    Form release / dosage:Solution for infusions 5%, 20%.
    Packaging:

    50, 100 ml of a 20% solution of albumin; 50, 100, 200, 400 ml for 5% solution in blood glass bottles, transfusion solutions with a capacity of 50, 100, 250,500 ml.

    For 10 and 20 ml for 5% and 20% solutions in ampoules with a capacity of 10 and 20 ml, respectively.

    Each bottle or 5, 10 ampoules, together with the instruction for use, is placed in a cardboard box.

    An ampoule knife is placed in a box with ampoules.

    Storage conditions:At a temperature of 2 to 10 ° C out of the reach of children. Special Precautionswhen there is no unused drug.
    Shelf life:

    5 years. Do not use after the time specified on the package.

    Terms of leave from pharmacies:On prescription
    Registration number:LSR-005651/09
    Date of registration:14.07.2009 / 30.04.2013
    Expiration Date:Unlimited
    The owner of the registration certificate:SAMARA REGION OF TRANSFUSION OF BLOOD SAMARA REGION OF TRANSFUSION OF BLOOD Russia
    Manufacturer: & nbsp
    Information update date: & nbsp15.07.2017
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