Albumin - instructions for use, dose, side effects, contraindications

Polypeptide, one of the main protein components of blood serum. Albumin is a natural protein that is an integral part of the protein fraction of human blood.

The molecular weight of albumin is 69,000 Da. Normally, human blood plasma for albumin accounts for about 60%. The synthesis of albumin occurs in the liver.

Pharmacological properties

Plasma-reducing agent obtained by fractionating human plasma. It replenishes the deficiency of plasma albumin, supports the colloid-osmotic (oncotic) blood pressure, rapidly increases blood pressure and circulating blood volume, increases the transition and promotes retention of tissue fluid in the bloodstream, increases the protein supply reserves of tissues and organs. It has detoxification properties.

Indications:Shock (traumatic, operational and toxic); burns accompanied by dehydration and "thickening" of blood; hypoproteinemia, hypoalbuminemia, developing with alimentary dystrophy, nephrotic syndrome, glomerulonephritis, cirrhosis, long-term ongoing purulent processes, lesions of the gastrointestinal tract with impaired absorption or patency.

Contraindications:

Hypersensitivity, severe anemia, chronic heart failure II + III stage, hypervolemia, pulmonary edema.

Carefully:Arterial hypertension, renal failure, thrombosis, ongoing intravenous bleeding, chronic heart failure of stage I.

Dosing and Administration:

Intravenously drip, 10% solution with a speed of §0 - 60 cap / min: single dose - 200 ml.

The dose is set individually depending on the indications and clinical picture or 1 -2 ml / kg of 10% solution daily until the effect is achieved.

Side effects:

Allergic reactions, hives, hyperthermia, pain in the lumbar region.

Special instructions:

Before transfusion of a solution of albumin 10% the doctor should conduct a visual inspection of the preparation and its containing containers.The solution should be clear and should not contain sediment and sediment. The drug is considered suitable for use under: condition of sealing and sealing, absence of cracks in vials, safety of the label. The results of visual inspection and data labels (the name of the drug, the manufacturer, batch number) are recorded in the history of the disease.

Introduction with dehydration is possible only after preliminary ensuring sufficient intake of fluid (by mouth, parenterally).

In the case of freezing during transport, the preparation can be used if, during thawing, it has not changed the appearance.

Form release / dosage:Solution for infusions 10%.

Packaging:

For 50, 100 and 200 ml in bottles of glass for blood, transfusion solutions with a capacity of 50. 100 and 250 ml.

Each bottle, along with the instructions for use, is placed in a cardboard box. Group packing without secondary (for hospital) 5 bottles per box of cardboard together with instructions for use (3 - 5 pcs).

Storage conditions:

At a temperature of 2 to 10 ° C out of the reach of children.

Shelf life:

5 years. Do not use after the time specified on the package.

Terms of leave from pharmacies:On prescription

Registration number:LSR-005894/08

Date of registration:23.07.2008 / 23.10.2012

Expiration Date:Unlimited

The owner of the registration certificate:BRYAN REGIONAL STATION OF BLOOD TRANSFUSION BRYAN REGIONAL STATION OF BLOOD TRANSFUSION Russia

Manufacturer: & nbsp

BRYAN REGIONAL STATION OF BLOOD TRANSFUSION Russia

Information update date: & nbsp15.07.2017

Illustrated instructions

Instructions

Albumen (Albumin)