Albumen (Albumin)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
Read on
Active substanceHuman albuminHuman albumin
Similar drugsTo uncover
  • Albionin 20%
    solution d / infusion 
    Biotest Pharma GmbH     Germany
  • Albumen
    solution d / infusion 
    MICROGEN FGUP Scientific and Production Association     Russia
  • Albumen
    solution d / infusion 
    STATION OF BLOOD TRANSFUSION OF KALININGRAD OBLAST, HBUZ     Russia
  • Albumen
    solution d / infusion 
    Kirov Research Institute of Hematology and Blood Transfusion, Federal State Institution     Russia
  • Albumen
    solution d / infusion 
    Chelyabinsk Regional Blood Transfusion Station     Russia
  • Albumen
    solution d / infusion 
    Chelyabinsk Regional Blood Transfusion Station     Russia
  • Albumen
    solution d / infusion 
    TAMBOV REGIONAL STATION OF BLOOD TRANSFUSION     Russia
  • Albumen
    solution d / infusion 
    SAMARA REGION OF TRANSFUSION OF BLOOD     Russia
  • Albumen
    solution d / infusion 
    LIPETSK REGIONAL STATION OF BLOOD TRANSFUSION     Russia
  • Albumen
    solution d / infusion 
    IVANOV REGIONAL STATION OF BLOOD TRANSFUSION     Russia
  • Albumen
    solution d / infusion 
    SAMARA REGION OF TRANSFUSION OF BLOOD     Russia
  • Albumen
    solution d / infusion 
    TYUMENS REGION OF TRANSFUSION OF BLOOD     Russia
  • Albumen
    solution d / infusion 
    IVANOV REGIONAL STATION OF BLOOD TRANSFUSION     Russia
  • Albumen
    solution d / infusion 
    TAMBOV REGIONAL STATION OF BLOOD TRANSFUSION     Russia
  • Albumen
    solution d / infusion 
    SVERDLOVSK REGIONAL STATION OF BLOOD TRANSFUSION OF GBUZ SO     Russia
  • Albumen
    solution d / infusion 
    SANGVIS SEC №2 СО СОЗ     Russia
  • Albumen
    solution d / infusion 
    BRYAN REGIONAL STATION OF BLOOD TRANSFUSION     Russia
  • Albumen
    solution d / infusion 
    Vologda Regional Blood Transfusion Station No.1     Russia
  • Albumen
    solution d / infusion 
    Nizhny Novgorod Regional Blood Center. N. Ya. Klimova     Russia
  • Human serum albumin
    solution d / infusion 
    Green Cross Corporation     The Republic of Korea
  • Human albumin
    solution d / infusion 
    Baxter AG     Austria
  • Human albumin
    solution d / infusion 
    Octapharma Pharmaceuticals Productionsgesb.H.     Austria
  • Alburex®
    solution d / infusion 
    CESEL Behring AG     Switzerland
  • Zenalb®-20
    solution d / infusion 
    Bio Products Laboratories Limited     United Kingdom
  • Zenalb-4,5
    solution d / infusion 
    Bio Products Laboratories Limited     United Kingdom
  • Plazbumin®-20
    solution d / infusion 
    Grifols Therapyutics Inc.     USA
  • Uman albumin
    solution d / infusion 
    Kedrion SpA     Italy
    • Dosage form: & nbspsolution for infusions
    Composition:

    One liter of solution contains:

    Active substances:

    Human albumin, produced from human blood plasma of venous origin. The preparation contains 200 g / l albumin.

    Excipients:

    sodium caprylate 6.0 g

    sodium chloride 9.0 g / l

    water for injection up to 1 liter

    Description:Transparent liquid is yellow, a greenish shade is allowed.
    Pharmacotherapeutic group:Plasmasuberant
    ATX: & nbsp

    B.05.A.A.01   Albumen

    Pharmacodynamics:

    Plasma-replacing agent obtained by fractionating human blood plasma. It replenishes the deficiency of blood plasma albumin, supports the colloid-osmotic (oncotic) blood pressure, rapidly increases blood pressure and circulating blood volume, promotes fluid transfer from tissues to the bloodstream, and has detoxification properties. Albumin is a natural protein, which is an integral part of the protein fraction of human blood, with a molecular weight of 69,000 daltons.

    Indications:

    Shock (traumatic, operational, toxic), burns, accompanied by dehydration and "thickening" of blood; hypoproteinemia, hypoalbuminemia, developing with alimentary dystrophy,nephrotic syndrome, glomerulonephritis, cirrhosis of the liver, long-term ongoing purulent processes, lesions of the gastrointestinal tract with impaired suction or patency.

    Contraindications:

    Increased individual sensitivity, hypervolemia, chronic heart failure II-IV functional class by NYHA, pulmonary edema, severe anemia.

    Carefully:

    Renal failure, hemorrhage, thrombosis, arterial hypertension.

    Pregnancy and lactation:

    Albumin solution should be used during pregnancy and during breastfeeding only if the potential benefit to the mother exceeds the possible risk to the fetus or child.

    Dosing and Administration:

    20% albumin solution intravenously drip at a speed of no more than 40-50 drops in a minute, Single dose is determined individually, taking into account age and severity the patient's condition; but not more 100 ml.

    In pediatric practice, albumin 20 % is prescribed in a dose of not more than 3 ml / kg of body weight.

    Elderly people should avoid the use of a 20% solution of albumin, since this can lead to an overload of the cardiovascular system.

    Side effects:

    Allergic reactions (urticaria, anaphylactic shock), chill, pyrexia, pain in the lumbar region.

    Overdose:

    At too high a dose or rate of infusion solution injection, hypervolemia can develop.

    In the first clinical signs of overload of the cardiovascular system (headache, dyspnea, overflow jugular vein) or at an elevated blood pressure, increased venous pressure, and pulmonary edema, the infusion should be stopped immediately and continuously monitor the patient's hemodynamic performance.

    Interaction:

    Compatible with standard electrolyte and carbohydrate solutions for intravenous infusion.

    The drug should not be mixed with protein hydrolysates, solutions of amino acids, with solutions containing alcohol.

    Special instructions:

    Before use, make visual inspection of the preparation and packaging: the solution should be clear that does not contain any inclusions glass packaging, to be sealed without cracks. In the case history, it is necessary to register the label data (name of the preparation, manufacturer, serial number, production date).After opening the bottle, the solution should be used immediately. Unused solution is not subject to storage.

    Administration of the drug during dehydration; it is possible only after preliminary ensuring sufficient supply of fluid (inside or parenteral).

    It is necessary to constantly monitor the patient's condition in order to avoid overloading the circulatory system or hyperhydration.

    When using drugs prepared from human plasma, it is impossible to completely eliminate the risk of transmission of known and as yet unknown virus infections.

    Form release / dosage:Solution for infusions 20%.
    Packaging:

    For 50 ml and 100 ml in bottles of glass for blood, transfusion and infusion preparations. For 1 bottle in a pack of cardboard along with instructions for use.

    For 10 and 20 ml in ampoules. For 10 or 5 ampoules in a pack of cardboard along with instructions for use.

    Storage conditions:

    At a temperature of 2 to 10 ° C. In a place inaccessible to children.

    Shelf life:

    5 years. Do not use after the expiration date.

    Terms of leave from pharmacies:On prescription
    Registration number:LP-000482
    Date of registration:01.03.2011 / 01.12.2015
    Expiration Date:Unlimited
    The owner of the registration certificate:Chelyabinsk Regional Blood Transfusion StationChelyabinsk Regional Blood Transfusion Station Russia
    Manufacturer: & nbsp
    Information update date: & nbsp15.07.2017
    Illustrated instructions
      Instructions
      Up