Decrease in albumin concentration in plasma less than 30 g / L or colloid osmotic (oncotic) pressure less than 15 mm Hg, or decrease in total plasma protein less than 50 g / l:
hypoalbuminemia of various genesis: shock (hemorrhagic, traumatic, thermal), acute blood loss (decrease in the volume of circulating blood by more than 25-30%); purulent-septic conditions; liver disease with violation of albumin-synthesizing function, kidney disease (nephritis, nephrotic syndrome), burn disease;
operations using artificial circulation; therapeutic plasmapheresis;
hemolytic disease of newborns during the exchange blood transfusion;
pre-operative hemodilution and preparation of autoblood components; swelling of the brain.