From the digestive system: Nausea, vomiting, diarrhea, abdominal pain, loose stools, flatulence, digestive disorders, anorexia, constipation, discoloration of the tongue, pseudomembranous colitis, cholestatic jaundice, hepatitis, changes in liver function tests, hepatic insufficiency, liver necrosis (possibly fatal ).
Allergic reactions: itching, skin rashes, angioedema, hives, photosensitization, anaphylactic reaction (in rare cases, fatal), erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis.
From the cardiovascular system: palpitation, arrhythmia, ventricular tachycardia, increased interval QT, bidirectional ventricular tachycardia.
From the nervous system: dizziness / vertigo, headache, seizures, drowsiness, paresthesia, asthenia, insomnia, hyperactivity, aggressiveness, anxiety, nervousness.
From the sense organs: noise in the ears, reversible hearing loss down to deafness (with high doses for a long time), a violation of the perception of taste and smell.
From the blood and lymphatic systems: thrombocytopenia, neutropenia, eosinophilia.
From the musculoskeletal system: arthralgia.
From the genitourinary system: interstitial nephritis, acute renal failure.
Other: vaginitis, candidiasis.