Dolgit - instructions for use, doses, side effects, contraindications

Excipients: medium chain triglycerides, purified water, glyceride monostearate, propylene glycol, macrogol-100-stearate, macrogol-30-stearate,gum xanthan (Keltrol F), sodium methylparahydroxybenzoate, lavender oil, orange flower oil (neroli oil).

Description:

Homogeneous, soft cream from white to white with a cream shade of color, with a slight specific smell.

Pharmacotherapeutic group:NSAIDs

ATX: & nbsp

M.01.A.E.01 Ibuprofen

Pharmacodynamics:

The drug has a local anesthetic, anti-inflammatory and anti-edematic effect. Suppresses the production of inflammatory mediators. It selectively blocks cyclooxygenase (COX-1 and COX-2) and has an inhibitory effect on the synthesis of prostaglandin E2 (PGE2), prostacyclin (PG12) and thromboxane B2 (TB2).

Analgesic effect is most pronounced for inflammatory pains. It causes a decrease or disappearance of the pain syndrome, including pain at rest and three movements; reduces the morning stiffness and swelling of the joints. Promotes an increase in the volume of movements.

In addition to the anti-inflammatory effect, ibuprofen reduces aggregation of platelets at the site of inflammation, as well as migration of leukocytes and release of lysosomal enzymes in the inflammation zone.

Pharmacokinetics:

When applying cream to the skin ibuprofen penetrates deeper tissues (subcutaneous fat, muscles, joints, synovial fluid) and reaches therapeutic concentrations in them. The therapeutic effect in the area of application is achieved by direct distribution through the skin in the target tissue. In an insignificant amount is determined in blood plasma. With the recommended method of application, the concentration in the synovial fluid is about 2 μg / ml.

Indications:

- Inflammatory and degenerative diseases of the musculoskeletal system: articular syndrome with exacerbation of gout, arthritis (rheumatoid, psoriatic, gouty), humeropathy periarthritis, ankylosing spondylitis (Bechterew's disease), deforming osteoarthritis, osteochondrosis with radicular syndrome, sciatica, tendonitis, tendovaginitis, bursitis , lumbago, sciatica.

- Muscle pain (myalgia) of rheumatic and non-rheumatic origin.

- Injuries (sports, industrial, household, etc.) without compromising the integrity of the skin (dislocations, sprains or ruptures of muscles and ligaments, bruises, posttraumatic swelling of soft tissues, etc.).

Contraindications:

Hypersensitivity to ibuprofen, the components of the drug and other NSAIDs, dermatoses, eczema,violation of the integrity of the skin (including infected abrasions and wounds) at the site of application of the cream; pregnancy, lactation; children's age till 14 years.

Dosing and Administration:

OUTSIDE! The cream is applied to the skin in the area of the painful area 3-4 times a day and rubbed with light movements until the drug is completely absorbed. A strip of cream 4-10 cm long is used depending on the area of the affected surface.

The duration of treatment depends on the severity of the disease and the nature of the lesion and is on average 2-3 weeks.

Side effects:

Usually the drug is well tolerated.

In rare cases, temporary signs of local irritation of the skin in the form of redness, swelling, rashes, itching of the skin, a burning sensation and tingling may occur.

In the case of hypersensitivity to NSAIDs, the phenomena of bronchospasm are possible.

With prolonged use of the drug in particularly sensitive patients, it is possible to develop systemic side effects.

Overdose:

Cases of cream overdose are not described.

At casual reception of a preparation inside it is necessary to clear a stomach (vomiting, reception of the activated coal) and to address to the doctor.

Further treatment, with Mr.Requisites, symptomatic.

Interaction:

You should consult your doctor before using the drug if you are using any other medicines.

Special instructions:

In severe cases, combined application of the cream is recommended externally with the administration of other NSAID dosage forms (parenterally, orally, rectally).

Avoid contact with eyes and other mucous membranes.

Effect on the ability to drive transp. cf. and fur:

The use of the drug does not affect the activity requiring increased attention, coordination of movements, high speed of mental and physical reactions (for example, in transport drivers, persons working with complex mechanisms, etc.).

Form release / dosage:Cream for external use, 5%.

Packaging:

In aluminum tubes of 20 g, 50 g and 100 g, sealed with a membrane and screwed on a plastic cap.

One tube with instructions for use in a cardboard pack.

Storage conditions:

Store in a dry place, at a temperature of 15-25 ° C.

Keep out of the reach of children.

Shelf life:3 years.

Do not use after the expiration date.

Terms of leave from pharmacies:Without recipe

Registration number:П N013399 / 01

Date of registration:23.07.2008

Expiration Date:Unlimited

The owner of the registration certificate:Dolorgit GmbH & Co. KGDolorgit GmbH & Co. KG Germany

Manufacturer: & nbsp

DOLORGIET, GmbH & Co. KG. KG Germany

Representation: & nbspDr. Thais Naturvaren Rus, Open CompanyDr. Thais Naturvaren Rus, Open Company

Information update date: & nbsp21.11.2016

Illustrated instructions

Instructions

Dolgit® (Dolgit®)